Full-length RNA-Seq of the RHOH gene in human B cells reveals new exons and splicing patterns

Autor: Frédéric Leprêtre, Jean-Pascal Meneboo, Céline Villenet, Laure Delestré, Bruno Quesnel, Carl Simon Shelley, Martin Figeac, Sylvie Galiègue-Zouitina

Publikováno v: Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)

Abstract The RhoH protein is a member of the Ras superfamily of guanosine triphosphate-binding proteins. RhoH is an atypical Rho family member that is always GTP-bound and thus always activated. It is restrictively expressed in normal hematopoietic c

Externí odkaz: https://doaj.org/article/0ec6757a24ae40658dd75c324332f55e

Deciphering genetic and nongenetic factors underlying tumour dormancy: insights from multiomics analysis of two syngeneic MRD models of melanoma and leukemia

Autor: Marie-Océane Laguillaumie, Sofia Titah, Aurélie Guillemette, Bernadette Neve, Frederic Leprêtre, Pascaline Ségard, Faruk Azam Shaik, Dominique Collard, Jean-Claude Gerbedoen, Léa Fléchon, Lama Hasan Bou Issa, Audrey Vincent, Martin Figeac, Shéhérazade Sebda, Céline Villenet, Jérôme Kluza, William Laine, Isabelle Fournier, Jean-Pascal Gimeno, Maxence Wisztorski, Salomon Manier, Mehmet Cagatay Tarhan, Bruno Quesnel, Thierry Idziorek, Yasmine Touil

Publikováno v: Biological Research, Vol 57, Iss 1, Pp 1-28 (2024)

Abstract Background Tumour dormancy, a resistance mechanism employed by cancer cells, is a significant challenge in cancer treatment, contributing to minimal residual disease (MRD) and potential relapse. Despite its clinical importance, the mechanism

Externí odkaz: https://doaj.org/article/a30941614df749d1805f6f87c1b51f5b

Patient-reported outcomes and experiences of migrants enrolled in a multidisciplinary HIV clinic with rapid, free, and onsite treatment dispensation: the ‘ASAP’ study

Autor: Anish K. Arora, Serge Vicente, Kim Engler, David Lessard, Edmundo Huerta, Joel Ishak, Nadine Kronfli, Jean-Pierre Routy, Joseph Cox, Benoit Lemire, Marina Klein, Alexandra de Pokomandy, Lina Del Balso, Giada Sebastiani, Isabelle Vedel, Amélie Quesnel-Vallée, Bertrand Lebouché, ASAP Migrant Advisory Committee

Publikováno v: AIDS Research and Therapy, Vol 21, Iss 1, Pp 1-13 (2024)

Abstract Background Scholars recommend providing migrants living with HIV (MLWH) with free treatment, rapidly, once linked to care to optimize their HIV-related experiences and health outcomes. Quantitative evaluations of patient-reported measures fo

Externí odkaz: https://doaj.org/article/ee4b34e3011845129d52702400ea36ef

The James Webb Space Telescope Mission: Optical Telescope Element Design, Development, and Performance

Autor: McElwain, Michael W., Feinberg, Lee D., Perrin, Marshall D., Clampin, Mark, Mountain, C. Matt, Lallo, Matthew D., Lajoie, Charles-Philippe, Kimble, Randy A., Bowers, Charles W., Stark, Christopher C., Acton, D. Scott, Aiello, Ken, Atkinson, Charles, Barinek, Beth, Barto, Allison, Basinger, Scott, Beck, Tracy, Bergkoetter, Matthew D., Bluth, Marcel, Boucarut, Rene A., Brady, Gregory R., Brooks, Keira J., Brown, Bob, Byard, John, Carey, Larkin, Carrasquilla, Maria, Celeste, Sid, Chae, Dan, Chaney, David, Chayer, Pierre, Chonis, Taylor, Cohen, Lester, Cole, Helen J., Comeau, Thomas M., Coon, Matthew, Coppock, Eric, Coyle, Laura, Davis, Rick, Dean, Bruce H., Dziak, Kenneth J., Eisenhower, Michael, Flagey, Nicolas, Franck, Randy, Gallagher, Benjamin, Gilman, Larry, Glassman, Tiffany, Golnik, Gary, Green, Joseph J., Grieco, John, Haase, Shari, Hadjimichael, Theodore J., Hagopian, John G., Hahn, Walter G., Hartig, George F., Havey, Keith A., Hayden, William L., Hellekson, Robert, Hicks, Brian, Holfeltz, Sherie T., Howard, Joseph M., Huguet, Jesse A., Jahne, Brian, Johnson, Leslie A., Johnston, John D., Jurling, Alden S., Kegley, Jeffrey R., Kennard, Scott, Keski-Kuha, Ritva A., Knight, J. Scott, Kulp, Bernard A., Levi, Joshua S., Levine, Marie B., Lightsey, Paul, Luetgens, Robert A., Mather, John C., Matthews, Gary W., McKay, Andrew G., Mehalick, Kimberly I., Meléndez, Marcio, Messer, Ted, Mosier, Gary E., Murphy, Jess, Nelan, Edmund P., Niedner, Malcolm B., Noël, Darin M., Ohara, Catherine M., Ohl, Raymond G., Olczak, Eugene, Osborne, Shannon B., Park, Sang, Patton, Kevin, Perrygo, Charles, Pueyo, Laurent, Quesnel, Lisbeth, Ranck, Dale, Redding, David C., Regan, Michael W., Reynolds, Paul, Rifelli, Rich, Rigby, Jane R., Sabatke, Derek, Saif, Babak N., Scorse, Thomas R., Seo, Byoung-Joon, Shi, Fang, Sigrist, Norbert, Smith, Koby, Smith, J. Scott, Smith, Erin C., Sohn, Sangmo Tony, Spina, John, Stahl, H. Philip, Telfer, Randal, Terlecki, Todd, Texter, Scott C., Van Buren, David, Van Campen, Julie M., Vila, Begoña, Voyton, Mark F., Waldman, Mark, Walker, Chanda B., Weiser, Nick, Wells, Conrad, West, Garrett, Whitman, Tony L., Wick, Eric, Wolf, Erin, Young, Greg, Zielinski, Thomas P.

The James Webb Space Telescope (JWST) is a large, infrared space telescope that has recently started its science program which will enable breakthroughs in astrophysics and planetary science. Notably, JWST will provide the very first observations of

Externí odkaz: http://arxiv.org/abs/2301.01779

A simulator-based autoencoder for focal plane wavefront sensing

Autor: Quesnel, Maxime, de Xivry, Gilles Orban, Absil, Olivier, Louppe, Gilles

Publikováno v: Proceedings Volume 12185, Adaptive Optics Systems VIII; 1218532 (2022)

Instrumental aberrations strongly limit high-contrast imaging of exoplanets, especially when they produce quasistatic speckles in the science images. With the help of recent advances in deep learning, we have developed in previous works an approach t

Externí odkaz: http://arxiv.org/abs/2211.05242