Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Quentin Van Thillo"'
Autor:
Matthias M. Engelen, Quentin Van Thillo, Albrecht Betrains, Iwein Gyselinck, Caroline P. Martens, Valérie Spalart, Anna Ockerman, Caroline Devooght, Joost Wauters, Jan Gunst, Carine Wouters, Christophe Vandenbriele, Steffen Rex, Laurens Liesenborghs, Alexander Wilmer, Philippe Meersseman, Greet Van den Berghe, Dieter Dauwe, Ann Belmans, Michiel Thomeer, Tom Fivez, Dieter Mesotten, David Ruttens, Luc Heytens, Ilse Dapper, Sebastiaan Tuyls, Brecht De Tavernier, Peter Verhamme, Thomas Vanassche, DAWn Consortium Members
Publikováno v:
Research and Practice in Thrombosis and Haemostasis, Vol 6, Iss 7, Pp n/a-n/a (2022)
Abstract Background Thromboinflammation plays a central role in severe COVID‐19. The kallikrein pathway activates both inflammatory pathways and contact‐mediated coagulation. We investigated if modulation of the thromboinflammatory response impro
Externí odkaz:
https://doaj.org/article/0b44d597e02c4aa1ae0a47b3c5ef8724
Autor:
Quentin Van Thillo, Jolien De Bie, Janith A. Seneviratne, Sofie Demeyer, Sofia Omari, Anushree Balachandran, Vicki Zhai, Wai L. Tam, Bram Sweron, Ellen Geerdens, Olga Gielen, Sarah Provost, Heidi Segers, Nancy Boeckx, Glenn M. Marshall, Belamy B. Cheung, Kiyotaka Isobe, Itaru Kato, Junko Takita, Timothy G. Amos, Ira W. Deveson, Hannah McCalmont, Richard B. Lock, Ethan P. Oxley, Maximilian M. Garwood, Ross A. Dickins, Anne Uyttebroeck, Daniel R. Carter, Jan Cools, Charles E. de Bock
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
SPI1 fusion genes in T-cell acute lymphoblastic leukemia (T-ALL) are commonly found with co-occurring NRAS mutations. Here, the authors show that the combination of these oncogenes is necessary to drive T-ALL in a murine model and that the oncogenic
Externí odkaz:
https://doaj.org/article/097bfb27edca4477bb37a09172ff1f71
Autor:
Iwein Gyselinck, Laurens Liesenborghs, Ann Belmans, Matthias M. Engelen, Albrecht Betrains, Quentin Van Thillo, Pham Anh Hong Nguyen, Pieter Goeminne, Ann-Catherine Soenen, Nikolaas De Maeyer, Charles Pilette, Emmanuelle Papleux, Eef Vanderhelst, Aurélie Derweduwen, Patrick Alexander, Bernard Bouckaert, Jean-Benoît Martinot, Lynn Decoster, Kurt Vandeurzen, Rob Schildermans, Peter Verhamme, Wim Janssens, Robin Vos
Publikováno v:
ERJ Open Research, Vol 8, Iss 1 (2022)
Background and objectives Azithromycin was rapidly adopted as a repurposed drug to treat coronavirus disease 2019 (COVID-19) early in the pandemic. We aimed to evaluate its efficacy in patients hospitalised for COVID-19. Methods In a series of random
Externí odkaz:
https://doaj.org/article/84e4d414b91948c480d8de7f8a801790
Autor:
Quentin Van Thillo, Barbara Dewaele, Jolien De Bie, Lucienne Michaux, Timothy Devos, Peter Vandenberghe
Publikováno v:
British Journal of Haematology.
Autor:
Marlies Vanden Bempt, Koen Debackere, Sofie Demeyer, Quentin Van Thillo, Nienke Meeuws, Cristina Prieto, Sarah Provost, Nicole Mentens, Kris Jacobs, Olga Gielen, David Nittner, Seishi Ogawa, Keisuke Kataoka, Carlos Graux, Thomas Tousseyn, Jan Cools, Daan Dierickx
Publikováno v:
Blood, (2022)
Peripheral T-cell lymphoma (PTCL) is a heterogeneous group of hematological cancers arising from the malignant transformation of mature T cells. In a cohort of 28 PTCL cases, we identified recurrent overexpression of MYCN, a member of the MYC family
Akademický článek
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Autor:
Timothy G. Amos, Janith A. Seneviratne, Quentin Van Thillo, Hannah McCalmont, Wai L. Tam, Jan Cools, Ira W. Deveson, Jolien De Bie, Sofie Demeyer, Nancy Boeckx, Richard B. Lock, Vicki Zhai, Sarah Provost, Kiyotaka Isobe, Junko Takita, Anne Uyttebroeck, Heidi Segers, Olga Gielen, Daniel R. Carter, Ethan P. Oxley, Charles E. de Bock, Bram Sweron, Maximilian M. Garwood, Belamy B. Cheung, Glenn M. Marshall, Ross A. Dickins, Anushree Balachandran, Itaru Kato, Ellen Geerdens, Sofia Omari
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Nature Communications
Nature Communications
Spi-1 Proto-Oncogene (SPI1) fusion genes are recurrently found in T-cell acute lymphoblastic leukemia (T-ALL) cases but are insufficient to drive leukemogenesis. Here we show that SPI1 fusions in combination with activating NRAS mutations drive an im