Výsledky vyhledávání - "Quentin Saintain"

Akademický článek

Broad functional profiling of fission yeast proteins using phenomics and machine learning

Autor: María Rodríguez-López, Nicola Bordin, Jon Lees, Harry Scholes, Shaimaa Hassan, Quentin Saintain, Stephan Kamrad, Christine Orengo, Jürg Bähler

Publikováno v: eLife, Vol 12 (2023)

Many proteins remain poorly characterized even in well-studied organisms, presenting a bottleneck for research. We applied phenomics and machine-learning approaches with Schizosaccharomyces pombe for broad cues on protein functions. We assayed colony

Externí odkaz: https://doaj.org/article/1e2e0ac5bcd64e5a95d52821d8b5c76a

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Akademický článek

R-loops and regulatory changes in chronologically ageing fission yeast cells drive non-random patterns of genome rearrangements.

Autor: David A Ellis, Félix Reyes-Martín, María Rodríguez-López, Cristina Cotobal, Xi-Ming Sun, Quentin Saintain, Daniel C Jeffares, Samuel Marguerat, Víctor A Tallada, Jürg Bähler

Publikováno v: PLoS Genetics, Vol 17, Iss 8, p e1009784 (2021)

Aberrant repair of DNA double-strand breaks can recombine distant chromosomal breakpoints. Chromosomal rearrangements compromise genome function and are a hallmark of ageing. Rearrangements are challenging to detect in non-dividing cell populations,

Externí odkaz: https://doaj.org/article/8b1f6da4c8ba46cd8aa5d831906597a2

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R-loops and regulatory changes in chronologically ageing fission yeast cells drive non-random patterns of genome rearrangements

Autor: Cristina Cotobal, Félix Reyes-Martín, David A. Ellis, Xi-Ming Sun, Victor A. Tallada, Quentin Saintain, María Rodríguez-López, Jürg Bähler, Daniel C. Jeffares, Samuel Marguerat

Publikováno v: PLoS Genetics, Vol 17, Iss 8, p e1009784 (2021)
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© 2021 Ellis et al.
Aberrant repair of DNA double-strand breaks can recombine distant chromosomal breakpoints. Chromosomal rearrangements compromise genome function and are a hallmark of ageing. Rearrangements are challenging to detect in non-d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f30e001ecf5be29d00db7cad5b71ff7
http://hdl.handle.net/10261/260242

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