Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Quentin N Pye"'
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0121977 (2015)
Inorganic catalytic nanoceria or cerium oxide nanoparticles (CeNPs) are bona fide antioxidants that possess regenerative radical scavenging activities in vitro. Previously, we demonstrated that CeNPs had neuroprotective and anti-angiogenic properties
Externí odkaz:
https://doaj.org/article/588b4b52af084f018793c0ccc41e43ab
Autor:
Kenneth Hensley, Joe Fedynyshyn, Scott Ferrell, Robert A Floyd, Brian Gordon, Paula Grammas, Ladan Hamdheydari, Molina Mhatre, Shenyun Mou, Quentin N Pye, Charles Stewart, Melinda West, Stuart West, Kelly S Williamson
Publikováno v:
Neurobiology of Disease, Vol 14, Iss 1, Pp 74-80 (2003)
Recent data indicate that certain pro-inflammatory cytokines are transcriptionally upregulated in the spinal cords of G93A-SOD1 mice, a model of amyotrophic lateral sclerosis (ALS). We previously showed that the receptor for tumor necrosis factor α
Externí odkaz:
https://doaj.org/article/aef449ec37e84535b7da5cef8f1913a1
Autor:
Lily L Wong, Suzanne M Hirst, Quentin N Pye, Christopher M Reilly, Sudipta Seal, James F McGinnis
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e58431 (2013)
Cerium oxide nanoparticles (nanoceria) possess catalytic and regenerative radical scavenging activities. The ability of nanoceria to maintain cellular redox balance makes them ideal candidates for treatment of retinal diseases whose development is ti
Externí odkaz:
https://doaj.org/article/8f59d12adbef4f2e92ed424a86af8f7f
Autor:
Quentin N. Pye, Sabrina Doblas, Debra Saunders, Nataliya Smith, Megan R. Lerner, Rheal A. Towner, Jessica Hoyle, Randy L. Jensen, Ting He
Publikováno v:
NMR in Biomedicine. 25:685-694
assessed from 1 H MRS using point-resolved spectroscopy (PRESS) [TE=24ms; TR=2500ms; variable pulse power and optimized relaxation delay (VAPOR) water suppression; 27-m La nd 8-mL voxels in rats and mice, respectively] at 7T. Alterations in metabolit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::97a1a83b4c69e718c9f9f268471da705
https://doi.org/10.1002/nbm.1785
https://doi.org/10.1002/nbm.1785
Autor:
Zili Zhai, Kenneth Hensley, Dario C. Ramirez, Hammad Akram, R. Hal Scofield, Biji T. Kurien, Sandra E. Gomez-Mejiba, Quentin N. Pye
Publikováno v:
Mutation Research/Genetic Toxicology and Environmental Mutagenesis. 674:62-72
Human life expectancy and welfare has decreased because of the increase in environmental stressors in the air. An environmental stressor is a natural or human-made component present in our environment that upon reaching an organic system produces a c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a9e348a9439a6f96892a2fa071635cf
https://doi.org/10.1016/j.mrgentox.2008.09.016
https://doi.org/10.1016/j.mrgentox.2008.09.016
Autor:
Kelly S. Williamson, Kenneth Hensley, Quentin N. Pye, J. Brad Morris, Chandrashekhar D. Kamat
Publikováno v:
Phytochemical Analysis. 19:311-322
The objective of this study was to determine the composition and content of sesamin and desmethyl tocopherols such as alpha-tocopherol (alphaT), delta-tocopherol (deltaT) and gamma-tocopherol (gammaT) in seeds of sesame (Sesamum indicum L.) for 11 ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4975ef2681cb85181b539ff16d8cbe8f
https://doi.org/10.1002/pca.1050
https://doi.org/10.1002/pca.1050
Autor:
Raha Nael, Xuan V. Nguyen, Nai-Ying Zheng, James W. Geddes, William R. Markesbery, Ela Patel, Kent A. Robinson, Kenneth Hensley, Robert A. Floyd, Guoying Bing, Charles A. Stewart, Quentin N. Pye, Gail V.W. Johnson
Publikováno v:
Journal of Neurochemistry. 72:2053-2058
The p38 mitogen-activated protein kinase is a stress-activated enzyme responsible for transducing inflammatory signals and initiating apoptosis. In the Alzheimer's disease (AD) brain, increased levels of phosphorylated (active) p38 were detected rela
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::622ba6c7031d9d757db4c53b62d28ffe
https://doi.org/10.1046/j.1471-4159.1999.0722053.x
https://doi.org/10.1046/j.1471-4159.1999.0722053.x
Autor:
Rheal A. Towner, Jenny Oblander, Quentin N. Pye, Stanley D. Kosanke, Brian Gordon, Preeti Kshirsagar, Debbie Saunders, Robert A. Floyd, Sabrina Doblas
Publikováno v:
Free Radical Biology and Medicine. 44:63-72
The prognosis of patients who are diagnosed with glioblastoma multiforme is very poor, due to the difficulty of an early and accurate diagnosis and the lack of currently efficient therapeutic compounds. The efficacy of phenyl-tert-butylnitrone (PBN)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8035c3fa705d18cacf8d7756afbbe65c
https://doi.org/10.1016/j.freeradbiomed.2007.09.006
https://doi.org/10.1016/j.freeradbiomed.2007.09.006
Autor:
Kelly S. Williamson, Padmaja Mehta, Melinda West, Jan Post, Kenneth Hensley, Quentin N. Pye, Shenyun Mou, Charles E. Stewart, Molina Mhatre, Rachel Wang, Charlotte H. Y. Chung, Biji T. Kurien, Lucy Liu
Publikováno v:
Biochemistry. 46:3262-3269
Proteomic experiments were performed to identify novel glutathione (GSH) binding proteins expressed in the mammalian central nervous system. Bovine brain lysate was affinity purified using an immobilized glutathione-Sepharose column. Proteins that bo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45a15d1c9be093226218aeea944848e3
https://doi.org/10.1021/bi061888s
https://doi.org/10.1021/bi061888s
Autor:
Robert H. Broyles, Charles A. Stewart, Robert A. Floyd, Wei-Xing Guo, Yashige Kotake, Kelly S. Williamson, Kenneth Hensley, Quentin N. Pye
Publikováno v:
Free Radical Biology and Medicine. 39:641-650
Our recent studies have demonstrated that generation of ROS is associated with choline deficiency (CD)-induced apoptosis in CWSV-1 cells, an immortalized rat hepatocyte that becomes tumorigenic by stepwise culturing in decreasing levels of choline. I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4201a15ee13a5ba3b740c4eb52e6541c
https://doi.org/10.1016/j.freeradbiomed.2005.04.013
https://doi.org/10.1016/j.freeradbiomed.2005.04.013