Zobrazeno 1 - 10
of 569
pro vyhledávání: '"Quentin M, Anstee"'
Autor:
Elena Sena, Frank Tacke, Quentin M. Anstee, Nicholas Di Prospero, Mette Skalshøi- Kjær, Sergio Muñoz-Martínez, Jesús Rivera-Esteban, Alba Jiménez-Masip, Jesús M. Bañales, María Martínez-Gómez, Franz Koenig, Joan Genescà, Vlad Ratziu, Juan M. Pericàs
Publikováno v:
Communications Medicine, Vol 4, Iss 1, Pp 1-8 (2024)
Abstract Background The EU Patient-cEntric clinicAl tRial pLatforms (EU-PEARL) project (IMI2-853966) aimed to develop tools to establish integrated research platforms (IRP) for conducting adaptive-design trials in various diseases, including metaboli
Externí odkaz:
https://doaj.org/article/56b347d335b94f00aa100ba39c9f7709
Autor:
Quentin M. Anstee, Jeremy Magnanensi, Yacine Hajji, Alexandra Caron, Zouher Majd, Christian Rosenquist, Dean W. Hum, Bart Staels, Margery A. Connelly, Rohit Loomba, Stephen A. Harrison, Vlad Ratziu, Arun J. Sanyal
Publikováno v:
JHEP Reports, Vol 6, Iss 4, Pp 101011- (2024)
Background & Aims: Robust performance of non-invasive tests (NITs) across ages is critical to assess liver disease among patients with metabolic dysfunction-associated liver disease (MASLD). We evaluated the impact of age on the performance of NIS2+
Externí odkaz:
https://doaj.org/article/e823e08beef848c0a1ad7f05022bf9e3
Autor:
James Twiss, Diane Whalley, Lynda Doward, Maria-Magdalena Balp, Clifford A. Brass, Donna Cryer, Arun Sanyal, Quentin M. Anstee
Publikováno v:
Journal of Patient-Reported Outcomes, Vol 7, Iss 1, Pp 1-14 (2023)
Abstract Background Standardized measures for evaluating patients’ experiences with nonalcoholic steatohepatitis (NASH) and their perceived changes with treatment in clinical trials have been limited. To meet this need, a patient-reported outcome (
Externí odkaz:
https://doaj.org/article/8b44ccc2a203433ba698e8da08c32158
Autor:
Jesús Funuyet-Salas, Agustín Martín-Rodríguez, María Ángeles Pérez-San-Gregorio, Luke Vale, Tomos Robinson, Quentin M Anstee, Manuel Romero-Gómez
Publikováno v:
PLoS ONE, Vol 19, Iss 5, p e0300362 (2024)
BackgroundIt is unclear what biopsychosocial factors influence the impact of NAFLD on health-related quality of life (HRQoL), and if these factors are equally important predictors between different nationalities.MethodsHRQoL (CLDQ) was measured in bo
Externí odkaz:
https://doaj.org/article/539503160996469980833a51f4ea298b
Autor:
Matthew McTeer, Douglas Applegate, Peter Mesenbrink, Vlad Ratziu, Jörn M Schattenberg, Elisabetta Bugianesi, Andreas Geier, Manuel Romero Gomez, Jean-Francois Dufour, Mattias Ekstedt, Sven Francque, Hannele Yki-Jarvinen, Michael Allison, Luca Valenti, Luca Miele, Michael Pavlides, Jeremy Cobbold, Georgios Papatheodoridis, Adriaan G Holleboom, Dina Tiniakos, Clifford Brass, Quentin M Anstee, Paolo Missier, LITMUS Consortium investigators
Publikováno v:
PLoS ONE, Vol 19, Iss 2, p e0299487 (2024)
AimsMetabolic dysfunction Associated Steatotic Liver Disease (MASLD) outcomes such as MASH (metabolic dysfunction associated steatohepatitis), fibrosis and cirrhosis are ordinarily determined by resource-intensive and invasive biopsies. We aim to sho
Externí odkaz:
https://doaj.org/article/67ecf06493dd4d75bdee07628520f62d
Autor:
Quentin M. Anstee, Tina L. Berentzen, Louise M. Nitze, Maximilian Jara, Anders B. Jensen, Mette S. Kjær, Kamal K. Mangla, Jens M. Tarp, Kamlesh Khunti
Publikováno v:
The Lancet Regional Health. Europe, Vol 36, Iss , Pp 100780- (2024)
Summary: Background: The Fibrosis-4 Index (FIB-4) is used as a non-invasive tool for the presence of advanced liver fibrosis in metabolic dysfunction-associated steatotic liver disease and type 2 diabetes. However, evidence for an association between
Externí odkaz:
https://doaj.org/article/c488c2956e07421ba7c561883a9cc720
Autor:
Mary E. Rinella, Jeffrey V. Lazarus, Vlad Ratziu, Sven M. Francque, Arun J. Sanyal, Fasiha Kanwal, Diana Romero, Manal F. Abdelmalek, Quentin M. Anstee, Juan Pablo Arab, Marco Arrese, Ramon Bataller, Ulrich Beuers, Jerome Boursier, Elisabetta Bugianesi, Christopher D. Byrne, Graciela E. Castro Narro, Abhijit Chowdhury, Helena Cortez-Pinto, Donna R. Cryer, Kenneth Cusi, Mohamed El-Kassas, Samuel Klein, Wayne Eskridge, Jiangao Fan, Samer Gawrieh, Cynthia D. Guy, Stephen A. Harrison, Seung Up Kim, Bart G. Koot, Marko Korenjak, Kris V. Kowdley, Florence Lacaille, Rohit Loomba, Robert Mitchell-Thain, Timothy R. Morgan, Elisabeth E. Powell, Michael Roden, Manuel Romero-Gómez, Marcelo Silva, Shivaram Prasad Singh, Silvia C. Sookoian, C. Wendy Spearman, Dina Tiniakos, Luca Valenti, Miriam B. Vos, Vincent Wai-Sun Wong, Stavra Xanthakos, Yusuf Yilmaz, Zobair Younossi, Ansley Hobbs, Marcela Villota-Rivas, Philip N. Newsome
Publikováno v:
Annals of Hepatology, Vol 29, Iss 1, Pp 101133- (2024)
The principal limitations of the terms NAFLD and NASH are the reliance on exclusionary confounder terms and the use of potentially stigmatising language. This study set out to determine if content experts and patient advocates were in favor of a chan
Externí odkaz:
https://doaj.org/article/f02c612b79da4aaa8837228f72393227
Autor:
Vincent Wai-Sun Wong, Quentin M. Anstee, Louise M. Nitze, Anja Geerts, Jacob George, Victor Nolasco, Mette S. Kjær, Steen Ladelund, Philip N. Newsome, Vlad Ratziu
Publikováno v:
EClinicalMedicine, Vol 66, Iss , Pp 102310- (2023)
Summary: Background: Currently, assessment of candidate pharmacotherapies in patients with non-alcoholic steatohepatitis (NASH) involves invasive liver biopsy. Non-invasive scores, such as the FibroScan-aspartate aminotransferase (FAST) score, are us
Externí odkaz:
https://doaj.org/article/be1241c16f2141948af877d3c5b51a1d
Publikováno v:
Mathematics, Vol 12, Iss 5, p 777 (2024)
Aims: Overlapping asymmetric data sets are where a large cohort of observations have a small amount of information recorded, and within this group there exists a smaller cohort which have extensive further information available. Missing imputation is
Externí odkaz:
https://doaj.org/article/936066c9cf9a4e22994fca26259b2eff
Autor:
Brian E. Ford, Shruti S. Chachra, Katrina Rodgers, Tabassum Moonira, Ziad H. Al-Oanzi, Quentin M. Anstee, Helen L. Reeves, Jörn M. Schattenberg, Rebecca J. Fairclough, David M. Smith, Dina Tiniakos, Loranne Agius
Publikováno v:
Molecular Metabolism, Vol 72, Iss , Pp 101722- (2023)
Objectives: The Glucokinase Regulatory Protein GKRP, encoded by GCKR, enables acute regulation of liver glucokinase to support metabolic demand. The common human GCKR rs1260326:Pro446 > Leu variant within a large linkage disequilibrium region associa
Externí odkaz:
https://doaj.org/article/bfd2b304f9c64daea275414d8bcedee8