Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Quentin Lefebvre"'
Publikováno v:
CHIMIA, Vol 74, Iss 10, Pp 803-807 (2020)
In highly competitive research environments, the ability to access more complex structural spaces efficiently is a predictor of a company's ability to generate novel IP-protected small molecule candidates with adequate properties, hence filling their
Externí odkaz:
https://doaj.org/article/e0a513cc78be4ce2aaf9afc3825d12e0
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 16, Iss 1, Pp 982-988 (2020)
Herein we report a workflow coupling photoredox-nickel dual-catalyzed N-arylation reactions to benchtop analysis for the efficient generation of fragment-based libraries. Technological advances in photoreactor design facilitated reliable and reproduc
Externí odkaz:
https://doaj.org/article/a4d81ec6fe1d43978be52fee352df0b8
Publikováno v:
iScience, Vol 6, Iss , Pp 102-113 (2018)
Summary: Carbon-carbon double bond (C=C) formation is a crucial transformation in organic chemistry. Visible-light photoredox catalysis provides economical and sustainable opportunities for the development of novel and peculiar organic reactions. Her
Externí odkaz:
https://doaj.org/article/3e0665ff291a437f85f862e65dddcf34
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 9, Iss 1, Pp 1883-1890 (2013)
A continuous flow oxidative photocyclization of stilbene derivatives has been developed which allows the scalable synthesis of backbone functionalized phenanthrenes and helicenes of various sizes in good yields.
Externí odkaz:
https://doaj.org/article/8e2a96ef56174b80bcd1143fc11b39d7
Autor:
Jan Petrovcic, Yaroslav Boyko D., Alexander S. Shved, Giovanni Lenardon, Christophe Salome, Quentin Lefebvre, Thomas Fessard, David Sarlah
Bioisosteric replacement is an indispensable tool in the medicinal chemist’s arsenal to strike a fine balance in multiparameter optimization campaigns and to deliver the best molecules for further preclinical development. The piperidine heterocycle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::108e58383ef576ce761718ac7b84c3d6
https://doi.org/10.26434/chemrxiv-2023-jgr4j
https://doi.org/10.26434/chemrxiv-2023-jgr4j
Publikováno v:
Helvetica Chimica Acta. 106
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b741ce842107c1e0c4fa8ba505918c2e
https://doi.org/10.1002/hlca.202200189
https://doi.org/10.1002/hlca.202200189
Autor:
Elliot Smith, Luke O'Brien, Kieran Jones, Stephen Argent, Christophe Salome, Quentin Lefebvre, Alain Valery, Graham Newton, Hon Wai Lam
Bridged or caged polycyclic hydrocarbons have rigid structures that project substituents into precise regions of 3D space, making them attractive as linking groups in materials science and as building blocks for medicinal chemistry. The efficient syn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2aa89e254ae9b2bb0f4be743b4b47093
https://doi.org/10.26434/chemrxiv-2023-l8q0t
https://doi.org/10.26434/chemrxiv-2023-l8q0t
Publikováno v:
Beilstein Journal of Organic Chemistry
Beilstein Journal of Organic Chemistry, Vol 16, Iss 1, Pp 982-988 (2020)
Beilstein Journal of Organic Chemistry, Vol 16, Iss 1, Pp 982-988 (2020)
Herein we report a workflow coupling photoredox-nickel dual-catalyzed N-arylation reactions to benchtop analysis for the efficient generation of fragment-based libraries. Technological advances in photoreactor design facilitated reliable and reproduc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97cf019de05dbaf79462084325cc23a6
http://europepmc.org/articles/PMC7237803
http://europepmc.org/articles/PMC7237803
Publikováno v:
Organic Chemistry Frontiers. 7:602-608
The addition of organometallic compounds to imines is a direct way for accessing α-branched secondary amines which are found in numerous bioactive molecules. Although convenient, such reactions typically involve the formation and isolation of the nu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::043d624eb9fc0742154c0f5712db28e0
https://doi.org/10.1039/c9qo01428d
https://doi.org/10.1039/c9qo01428d
Publikováno v:
Comprehensive Heterocyclic Chemistry IV ISBN: 9780128186565
Comprehensive Heterocyclic Chemistry IV
Comprehensive Heterocyclic Chemistry IV
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1e9cc9edc64eeed8363f5539d9a87a03
https://doi.org/10.1016/b978-0-12-818655-8.00161-x
https://doi.org/10.1016/b978-0-12-818655-8.00161-x