The transplantation of the gut microbiome of fat-1 mice protects against colonic mucus layer disruption and endoplasmic reticulum stress induced by high fat diet

Autor: Amina Bourragat, Quentin Escoula, Sandrine Bellenger, Olivier Zemb, Martin Beaumont, Killian Chaumonnot, Jean-Pierre Farine, Emmanuel Jacotot, Aline Bonnotte, Laure Avoscan, Jeanine Lherminier, Kangjia Luo, Michel Narce, Jérôme Bellenger

Publikováno v: Gut Microbes, Vol 16, Iss 1 (2024)

ABSTRACTHigh-fat diets alter gut barrier integrity, leading to endotoxemia by impacting epithelial functions and inducing endoplasmic reticulum (ER) stress in intestinal secretory goblet cells. Indeed, ER stress, which is an important contributor to

Externí odkaz: https://doaj.org/article/b3d0b6ff65bb40b1b2dc484b33e0e708

N-3 polyunsaturated fatty acids: An innovative strategy against obesity and related metabolic disorders, intestinal alteration and gut microbiota dysbiosis

Autor: Jérôme Bellenger, Quentin Escoula, Célia Bidu, Sandrine Bellenger, Michel Narce

Publikováno v: Biochimie
Biochimie, 2019, 159, pp.66-71. ⟨10.1016/j.biochi.2019.01.017⟩

Obesity is now widely recognized to be associated with low-grade systemic inflammation. It has been shown that high-fat feeding modulates gut microbiota which strongly increased intestinal permeability leading to lipopolysaccharide absorption causing

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b0a0e501d88aeac3489f92e5edb9a7e
https://hal.archives-ouvertes.fr/hal-03486871

Periodontitis induced byPorphyromonas gingivalisdrives periodontal microbiota dysbiosis and insulin resistance via an impaired adaptive immune response

Autor: Pascale Klopp, Simon Nicolas, Matteo Serino, Pascale Loubieres, Rémy Burcelin, Céline Pomié, André Colom, Martine Bonnaure-Mallet, Vincent Blasco-Baque, Sandrine Le Gall-David, Vincent Azalbert, Mathieu Lemaitre, Quentin Escoula, Aurélie Waget, Lucile Garidou, Philippe Kémoun

Publikováno v: Gut
Gut, BMJ Publishing Group, 2017, 66 (5), pp.872-885. ⟨10.1136/gutjnl-2015-309897⟩
Gut, 2017, 66 (5), pp.872-885. ⟨10.1136/gutjnl-2015-309897⟩

International audience; OBJECTIVE: To identify a causal mechanism responsible for the enhancement of insulin resistance and hyperglycaemia following periodontitis in mice fed a fat-enriched diet. DESIGN: We set-up a unique animal model of periodontit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ade10ab19bcbd38aa75d795c2ef7256a
https://doi.org/10.1136/gutjnl-2015-309897

The Transplantation of ω3 PUFA-Altered Gut Microbiota of Fat-1 Mice to Wild-Type Littermates Prevents Obesity and Associated Metabolic Disorders

Autor: Patrice D. Cani, Aymé Spor, Sandrine Bellenger, Quentin Escoula, Audrey Geissler, Michel Narce, André Bouchot, Maxime Galan, Dominique Dardevet, Laurent Lagrost, Jérôme Bellenger, Célia Bidu, Béatrice Morio

Publikováno v: Diabetes
Diabetes, 2018, 67 (8), pp.1512-1523. ⟨10.2337/db17-1488⟩
Diabetes, American Diabetes Association, 2018, 67 (8), pp.1512-1523. ⟨10.2337/db17-1488⟩
Diabetes, Vol. 67, no.8, p. 1512-1523 (2018)

IF 7.273 (2017); International audience; Altering the gut microbiome may be beneficial to the host, and it recently arose as a promising strategy to manage obesity. Here, we investigated the relative contribution of ω3 polyunsaturated fatty acid (PU

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16a6963a61ce2c3f4aca8990518a883f
https://u-bourgogne.hal.science/hal-01835624