Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Quentin Bourgeois-Jaarsma"'
Publikováno v:
Molecular and Cellular Neuroscience, 112:103613. Academic Press Inc.
Bourgeois-Jaarsma, Q, Miaja Hernandez, P & Groffen, A J 2021, ' Ca 2+ sensor proteins in spontaneous release and synaptic plasticity : Limited contribution of Doc2c, rabphilin-3a and synaptotagmin 7 in hippocampal glutamatergic neurons ', Molecular and Cellular Neuroscience, vol. 112, 103613 . https://doi.org/10.1016/j.mcn.2021.103613
Bourgeois-Jaarsma, Q, Miaja Hernandez, P & Groffen, A J 2021, ' Ca2+ sensor proteins in spontaneous release and synaptic plasticity: Limited contribution of Doc2c, rabphilin-3a and synaptotagmin 7 in hippocampal glutamatergic neurons ', Molecular and Cellular Neuroscience, vol. 112, 103613 . https://doi.org/10.1016/j.mcn.2021.103613
Bourgeois-Jaarsma, Q, Miaja Hernandez, P & Groffen, A J 2021, ' Ca 2+ sensor proteins in spontaneous release and synaptic plasticity : Limited contribution of Doc2c, rabphilin-3a and synaptotagmin 7 in hippocampal glutamatergic neurons ', Molecular and Cellular Neuroscience, vol. 112, 103613 . https://doi.org/10.1016/j.mcn.2021.103613
Bourgeois-Jaarsma, Q, Miaja Hernandez, P & Groffen, A J 2021, ' Ca2+ sensor proteins in spontaneous release and synaptic plasticity: Limited contribution of Doc2c, rabphilin-3a and synaptotagmin 7 in hippocampal glutamatergic neurons ', Molecular and Cellular Neuroscience, vol. 112, 103613 . https://doi.org/10.1016/j.mcn.2021.103613
Presynaptic neurotransmitter release is strictly regulated by SNARE proteins, Ca2+ and a number of Ca2+ sensors including synaptotagmins (Syts) and Double C2 domain proteins (Doc2s). More than seventy years after the original description of spontaneo
Publikováno v:
Molecular and cellular neurosciences. 112
Presynaptic neurotransmitter release is strictly regulated by SNARE proteins, Ca
Autor:
Rocío Díez-Arazola, Marieke Meijer, Alexander J. Groffen, Quentin Bourgeois-Jaarsma, L. Niels Cornelisse, Matthijs Verhage
Publikováno v:
Journal of Neuroscience, 40(13), 2606-2617. Society for Neuroscience
Díez-Arazola, R, Meijer, M, Bourgeois-Jaarsma, Q, Niels Cornelisse, L, Verhage, M & Groffen, A J 2020, ' Doc2 proteins are not required for the increased spontaneous release rate in synaptotagmin-1-deficient neurons ', Journal of Neuroscience, vol. 40, no. 13, pp. 2606-2617 . https://doi.org/10.1523/JNEUROSCI.0309-19.2020
J Neurosci
The Journal of neuroscience : the official journal of the Society for Neuroscience, 40(13), 2606-2617. Society for Neuroscience
Díez-Arazola, R, Meijer, M, Bourgeois-Jaarsma, Q, Cornelisse, L N, Verhage, M & Groffen, A J 2020, ' Doc2 Proteins Are Not Required for the Increased Spontaneous Release Rate in Synaptotagmin-1-Deficient Neurons ', The Journal of neuroscience : the official journal of the Society for Neuroscience, vol. 40, no. 13, pp. 2606-2617 . https://doi.org/10.1523/JNEUROSCI.0309-19.2020
Díez-Arazola, R, Meijer, M, Bourgeois-Jaarsma, Q, Niels Cornelisse, L, Verhage, M & Groffen, A J 2020, ' Doc2 proteins are not required for the increased spontaneous release rate in synaptotagmin-1-deficient neurons ', Journal of Neuroscience, vol. 40, no. 13, pp. 2606-2617 . https://doi.org/10.1523/JNEUROSCI.0309-19.2020
J Neurosci
The Journal of neuroscience : the official journal of the Society for Neuroscience, 40(13), 2606-2617. Society for Neuroscience
Díez-Arazola, R, Meijer, M, Bourgeois-Jaarsma, Q, Cornelisse, L N, Verhage, M & Groffen, A J 2020, ' Doc2 Proteins Are Not Required for the Increased Spontaneous Release Rate in Synaptotagmin-1-Deficient Neurons ', The Journal of neuroscience : the official journal of the Society for Neuroscience, vol. 40, no. 13, pp. 2606-2617 . https://doi.org/10.1523/JNEUROSCI.0309-19.2020
Regulated secretion is controlled by Ca2+sensors with different affinities and subcellular distributions. Inactivation ofSyt1(synaptotagmin-1), the main Ca2+sensor for synchronous neurotransmission in many neurons, enhances asynchronous and spontaneo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c6fac2e415a31bb081cdbdee4f46762
https://research.vumc.nl/en/publications/73139300-be10-4fed-a9cd-7054ccc879ae
https://research.vumc.nl/en/publications/73139300-be10-4fed-a9cd-7054ccc879ae
Publikováno v:
Bourgeois-Jaarsma, Q, Verhage, M & Groffen, A J 2019, ' Doc2b Ca 2+ binding site mutants enhance synaptic release at rest at the expense of sustained synaptic strength ', Scientific Reports, vol. 9, no. 1, 14408 . https://doi.org/10.1038/s41598-019-50684-1
Scientific Reports, 9(1):14408. Nature Publishing Group
Bourgeois-Jaarsma, Q, Verhage, M & Groffen, A J 2019, ' Doc2b Ca2+ binding site mutants enhance synaptic release at rest at the expense of sustained synaptic strength ', Scientific Reports, vol. 9, no. 1, 14408, pp. 14408 . https://doi.org/10.1038/s41598-019-50684-1
Scientific Reports, Vol 9, Iss 1, Pp 1-16 (2019)
Scientific Reports
Scientific Reports, 9(1):14408. Nature Publishing Group
Bourgeois-Jaarsma, Q, Verhage, M & Groffen, A J 2019, ' Doc2b Ca2+ binding site mutants enhance synaptic release at rest at the expense of sustained synaptic strength ', Scientific Reports, vol. 9, no. 1, 14408, pp. 14408 . https://doi.org/10.1038/s41598-019-50684-1
Scientific Reports, Vol 9, Iss 1, Pp 1-16 (2019)
Scientific Reports
Communication between neurons involves presynaptic neurotransmitter release which can be evoked by action potentials or occur spontaneously as a result of stochastic vesicle fusion. The Ca2+-binding double C2 proteins Doc2a and –b were implicated i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38194d0edec799707d361cf8f5007a4e
https://research.vu.nl/en/publications/5cb5e8df-6983-42ab-a304-c437dcab955b
https://research.vu.nl/en/publications/5cb5e8df-6983-42ab-a304-c437dcab955b
Communication between neurons involves presynaptic neurotransmitter release which can be evoked by action potentials or occur spontaneously as a result of stochastic vesicle fusion. The Ca2+-binding double C2proteins Doc2a and –b regulate both spon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b181c21f24177767595e3978e3a80912
Autor:
Roberta, Mancini, Tobias, van der Bijl, Quentin, Bourgeois-Jaarsma, Rizky, Lasabuda, Alexander J, Groffen
Publikováno v:
Scientific Reports
Recent advances in live Ca2+ imaging with increasing spatial and temporal resolution offer unprecedented opportunities, but also generate an unmet need for data processing. Here we developed SICT, a MATLAB program that automatically identifies rapid
Autor:
Quentin Bourgeois-Jaarsma, Alexander J. Groffen, Rizky Lasabuda, Roberta Mancini, Tobias van der Bijl
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-13 (2018)
Scientific Reports, 8(1):15523. Nature Publishing Group
Mancini, R, van der Bijl, T, Bourgeois-Jaarsma, Q, Lasabuda, R & Groffen, A J 2018, ' SICT : automated detection and supervised inspection of fast Ca 2+ transients ', Scientific Reports, vol. 8, 15523, pp. 1-13 . https://doi.org/10.1038/s41598-018-33847-4
Mancini, R, van der Bijl, T, Bourgeois-Jaarsma, Q, Lasabuda, R & Groffen, A J 2018, ' SICT: automated detection and supervised inspection of fast Ca2+ transients ', Scientific Reports, vol. 8, no. 1, 15523 . https://doi.org/10.1038/s41598-018-33847-4
Scientific Reports, 8:15523, 1-13. Nature Publishing Group
Scientific Reports, 8(1):15523. Nature Publishing Group
Mancini, R, van der Bijl, T, Bourgeois-Jaarsma, Q, Lasabuda, R & Groffen, A J 2018, ' SICT : automated detection and supervised inspection of fast Ca 2+ transients ', Scientific Reports, vol. 8, 15523, pp. 1-13 . https://doi.org/10.1038/s41598-018-33847-4
Mancini, R, van der Bijl, T, Bourgeois-Jaarsma, Q, Lasabuda, R & Groffen, A J 2018, ' SICT: automated detection and supervised inspection of fast Ca2+ transients ', Scientific Reports, vol. 8, no. 1, 15523 . https://doi.org/10.1038/s41598-018-33847-4
Scientific Reports, 8:15523, 1-13. Nature Publishing Group
Recent advances in live Ca2+ imaging with increasing spatial and temporal resolution offer unprecedented opportunities, but also generate an unmet need for data processing. Here we developed SICT, a MATLAB program that automatically identifies rapid