Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Queenie P. Vong"'
Autor:
Wai-Hang Leung, Wing Leung, Ying Li, David Bouck, Taosheng Chen, Queenie P. Vong, Susanne Wendt, Wenwei Lin, Erin Sullivan, Rafijul Bari
Publikováno v:
The Journal of Immunology. 194:2930-2941
Many malignant cells release the NKG2D ligand ULBP2 from their cell surface to evade immunosurveillance by NK cells and CD8 T cells. Although the shedding mechanism remains unclear, various inhibitors of matrix metalloproteinases have been shown to e
Publikováno v:
Molecular Biology of the Cell
Using mouse knockout strategy, the authors uncovered a role for Borg5 in microvascular angiogenesis. In primary mouse cardiac endothelial cells, Borg5 interacts with septin cytoskeleton and colocalizes with perinuclear actomyosin fibers. The data pre
Modulation of NKG2D ligand expression and metastasis in tumors by spironolactone via RXRγ activation
Publikováno v:
The Journal of Experimental Medicine
The diuretic drug spironolactone up-regulates NKG2D ligand expression in colon cancer cells via activation of the ATM–Chk2–mediated checkpoint pathway to enhance the antitumor function of NK cells.
Tumor metastasis and lack of NKG2D ligand (
Tumor metastasis and lack of NKG2D ligand (
Autor:
Wai-Hang Leung, Martha Holladay, Wing Leung, Barbara Rooney, Wing Keung Chan, Neha Das Gupta, Teresa M. Bell, Queenie P. Vong, Rafijul Bari
Publikováno v:
Blood. 114:5182-5190
Killer immunoglobulin-like receptors (KIRs) play an essential role in the regulation of natural killer cell functions. KIR genes are highly polymorphic in nature, showing both haplotypic and allelic variations among people. We demonstrated in both in
Autor:
James R. Downing, Queenie P. Vong, Guolian Kang, Kwan Gan, Ying Li, Yinmei Zhou, Victoria Turner, Wing Keung Chan, Cheng Cheng, Rafijul Bari, Wing Leung, Sheila A. Shurtleff, Christine Hartford, Ching-Hon Pui
Publikováno v:
Scientific Reports
Graft-versus-host disease (GVHD) is a major cause of morbidity and mortality after allogeneic hematopoietic stem cell transplantation (HSCT). To identify recipient risk factors, a genome-wide study was performed including 481,820 single-nucleotide po
Autor:
Barbara Rooney, Jim Houston, Ying Li, Wai-Hang Leung, Queenie P. Vong, Martha Holladay, Robert A.J. Oostendorp, Wing Leung
Thymocyte selection-associated high mobility group box protein family member 2 (TOX2) is a transcription factor belonging to the TOX family that shares a highly conserved high mobility group DNA-binding domain with the other TOX members. Although TOX
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2951f97e29b071e0eb7f6426cab04020
https://europepmc.org/articles/PMC4282154/
https://europepmc.org/articles/PMC4282154/
Autor:
Queenie P. Vong, Barbara Rooney, Martha Holladay, Andrew M. Davidoff, Wing Leung, Timothy D. Lockey, Wing Keung Chan, Piya Rujkijyanont, Paul Eldridge
Publikováno v:
Cancer research. 73(8)
Despite the use of intensive contemporary multimodal therapy, the overall survival of patients with high-risk neuroblastoma is still less than 50%. Therefore, immunotherapy without cross-resistance and overlapping toxicity has been proposed. In this
Publikováno v:
Current Protocols in Stem Cell Biology
Mouse embryonic stem (ES) cell is a unique yet highly successful system to study stem cell maintenance and differentiation. In this protocol, we describe the generation of engineered mouse ES cells that stably express GFP alone or GFP fused with hist
Autor:
Queenie P. Vong, Yunmin Li, Diana L. Alba, Wai-Yee Chan, Vanessa Baxendale, Shao-Ming Wu, Yun-Fai Chris Lau, Tin-Lap Lee, Owen M. Rennert
Publikováno v:
Journal of genetics and genomics = Yi chuan xue bao. 36(4)
Despite the identification of key genes such as Sry integral to embryonic gonadal development, the genomic classification and identification of chromosomal activation of this process is still poorly understood. To better understand the genetic regula
Publikováno v:
The FASEB Journal. 21