Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Queenie Lai Kwan Lam"'
Publikováno v:
The Journal of biological chemistry. 295(34)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36577642503bc628b93bf303095d9dc3
https://pubmed.ncbi.nlm.nih.gov/17660512
https://pubmed.ncbi.nlm.nih.gov/17660512
Publikováno v:
Proceedings of the National Academy of Sciences. 105:14993-14998
Rheumatoid arthritis (RA) is a chronic disease characterized by synovial inflammation and joint damage. Although both T cells and B cells mediate the disease pathogenesis, proinflammatory cytokines are critically involved. The TNF superfamily member
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01f9058d1ae88e5f25079b39ff5cc954
https://doi.org/10.1073/pnas.0806044105
https://doi.org/10.1073/pnas.0806044105
Autor:
Queenie Lai Kwan Lam, Huaxi Xu, Bo-Jian Zheng, Changyou Wu, King-Hung Ko, Cherry Kam Chun Lo, Lingyun Sun, Liwei Lu, Shengjun Wang
Publikováno v:
Arthritis & Rheumatism. 58:2700-2711
Objective An altered phenotype and dysfunction of natural killer (NK) cells have been observed in patients with rheumatoid arthritis. The aim of this study was to determine whether dysregulated NK cells contribute to the pathogenesis of experimental
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23d6f6436dea06a3801f65529347cc8c
https://doi.org/10.1002/art.23760
https://doi.org/10.1002/art.23760
Publikováno v:
J Biol Chem
Increasing evidence suggests a regulatory role for leptin, an adipocyte-derived hormone, in immunity. Although recent studies indicated an essential role of leptin signaling in dendritic cell (DC) maturation, the molecular mechanisms by which leptin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b2709d62f0586063bf5ee93eaa2efd2
https://doi.org/10.1074/jbc.m704579200
https://doi.org/10.1074/jbc.m704579200
Autor:
Queenie Lai Kwan Lam, Xun Qu, Qianqian Shao, Meixiang Yang, Liwei Lu, Beihua Kong, Biping Deng, King-Hung Ko
Publikováno v:
Immunology and Cell Biology. 84:557-562
Dendritic cells (DC) are highly mobile APC. The trafficking of both immature and mature DC is crucial for their functions, which depends mainly on chemotactic attraction and matrix metalloproteinases (MMP) activity. MMP that are in a transmembrane fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87bf21a265fa2ec58a16f98e0553d629
https://doi.org/10.1111/j.1440-1711.2006.01465.x
https://doi.org/10.1111/j.1440-1711.2006.01465.x
Autor:
Liwei Lu, Min Zhang, Shi Yan, Beihua Kong, Meixiang Yang, Xun Qu, Lan Qi, Queenie Lai Kwan Lam, Peng Li
Publikováno v:
Immunology & Cell Biology. 83:668-673
Hypoxia, a prominent characteristic of inflammatory tissue lesions and solid tumour microenvironments, is a crucial stimulus capable of modulating the expression of specific genes involved in leucocyte recruitment. Although studies have shown that hy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0527063669f3ec69db631dde8aa6ab9c
https://doi.org/10.1111/j.1440-1711.2005.01383.x
https://doi.org/10.1111/j.1440-1711.2005.01383.x
Autor:
Yu-Lung Lau, Min Zhang, Queenie Lai Kwan Lam, Liwei Lu, Cherry Kam Chun Lo, Bo-Jian Zheng, King-Hung Ko, Gopesh Srivastava
Publikováno v:
International Immunology. 17:1081-1092
B cell-activating factor (BAFF), a member of tumor necrosis factor family cytokines, has been shown to enhance the maturation and survival of peripheral B cells. While BAFF is implicated in regulating B cell function and autoimmunity, its role in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::343b995c2536d57907b4c4a03895a1c5
https://doi.org/10.1093/intimm/dxh287
https://doi.org/10.1093/intimm/dxh287
Publikováno v:
Nucleic Acids Research. 27:2304-2309
It has long been appreciated that some immunoglobulin (and T-cell receptor) gene segments are used much more frequently than others. The VHsegment V81x is a particularly striking case of overusage. Its usage varies with the stage of B-cell developmen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4dbb5e36e22378e708aac034a132f35
https://doi.org/10.1093/nar/27.11.2304
https://doi.org/10.1093/nar/27.11.2304
Regulation of apoptosis and cell cycle progression plays an essential role in the maintenance of B-cell homeostasis, because a fine balance of survival and expansion is critical for preventing lymphocytic disorders. Although remarkable progress in un
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35c5b9b3a2fa5bd34a9d60edecdad831
http://hdl.handle.net/10722/129510
http://hdl.handle.net/10722/129510
Autor:
Changyou Wu, Cherry Kam Chun Lo, Rui Ma, Huaxi Xu, Lingyun Sun, Min Yang, King-Hung Ko, Queenie Lai Kwan Lam, Sidney Tam, Liwei Lu, Shengjun Wang, Bo-Jiang Zheng
Publikováno v:
Cellularmolecular immunology. 6(5)
Increasing evidence indicates a role of leptin in immune response, but it remains largely unclear whether leptin signaling is involved in regulating NK cell development in the bone marrow (BM). In this study, we have characterized NK cell differentia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e3d04fc17a935ac83ff09219f2ab566
https://pubmed.ncbi.nlm.nih.gov/19887048
https://pubmed.ncbi.nlm.nih.gov/19887048