Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Que Chi Truong"'
Autor:
Que Chi Truong-Bolduc, Chun-Hsing Liao, Hidemasa Nakaminami, Jacob Strahilevitz, Leon G. Leanse
Publikováno v:
Frontiers in Microbiology, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/3bff6738d04c44c3a58f98203e220026
Publikováno v:
Infect Immun
The Staphylococcus aureus Tet38 membrane protein has distinct functions, including drug efflux and host cell attachment and internalization mediated by interaction with host cell CD36. Using structural modeling and site-directed mutagenesis, we ident
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03663afbcfe93cf9b100d4bb5e3c7adb
https://pubmed.ncbi.nlm.nih.gov/33619028
https://pubmed.ncbi.nlm.nih.gov/33619028
Publikováno v:
Infection and Immunity. 87
Using an affinity column retention assay, we showed that the purified Tet38 membrane transporter of Staphylococcus aureus bound specifically to host cell CD36 and to the complex CD36–Toll-like receptor 2 (TLR-2), but not to TLR-2 alone or TLR-2 and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ea0ef1a7ef5918e6d1612310f7a6ee6
https://doi.org/10.1128/iai.00194-19
https://doi.org/10.1128/iai.00194-19
Fosfomycin inhibits MurA following uptake by the GlpT transporter of glycerol-3-phosphate in Escherichia coli . In Staphylococcus aureus , plasmid overexpression of the Tet38 efflux pump and a glpT mutant resulted in increased MICs and decreased accu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7303f2500161f09f3e545fa8e8c5211d
https://europepmc.org/articles/PMC6105802/
https://europepmc.org/articles/PMC6105802/
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1700
In this chapter, we describe the step-by-step identification of a putative regulator protein and demonstrate the function of this protein as a repressor of the expression of a specific efflux pump, causing resistance to quinolones in Staphylococcus a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::552f01865ebca30392a9aedb2804eee1
https://pubmed.ncbi.nlm.nih.gov/29177836
https://pubmed.ncbi.nlm.nih.gov/29177836
Autor:
David C. Hooper, Que Chi Truong-Bolduc
Publikováno v:
Methods in Molecular Biology ISBN: 9781493974528
In this chapter, we describe the step-by-step identification of a putative regulator protein and demonstrate the function of this protein as a repressor of the expression of a specific efflux pump, causing resistance to quinolones in Staphylococcus a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aa2eae8134d131d9f86ccd2bc0d3a65a
https://doi.org/10.1007/978-1-4939-7454-2_15
https://doi.org/10.1007/978-1-4939-7454-2_15
Autor:
Hidemasa Nakaminami, Eu Suk Kim, David C. Hooper, Chunhui Chen, Yin Wang, Que Chi Truong-Bolduc
Publikováno v:
Infection and immunity. 85(8)
The siderophores staphyloferrin A (SA) and staphyloferrin B (SB) of Staphylococcus aureus are essential for iron acquisition in the iron-restricted environment of the host, such as in subcutaneous abscesses. SA and SB are secreted by SfaA and SbnD tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79cacd5862ede9dda26f346917ad1a53
https://pubmed.ncbi.nlm.nih.gov/28559406
https://pubmed.ncbi.nlm.nih.gov/28559406
Publikováno v:
Antimicrobial agents and chemotherapy. 61(8)
TetR21 controls the expression of Tet38 and LmrS efflux pumps. A tetR21 mutant, QT21, exhibited a 4-fold increase in the transcription level of lmrS . Staphylococcus aureus lmrS overexpressor showed increases of 4-fold and 2-fold, respectively, in th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75dfb98e1b9d541be1d54efbb3ea090e
https://pubmed.ncbi.nlm.nih.gov/28584148
https://pubmed.ncbi.nlm.nih.gov/28584148
Autor:
Que Chi Truong-Bolduc, David C. Hooper, Yin Wang, Heidi Medeiros, Zoe Estabrooks, Régis Villet
Publikováno v:
Journal of Bacteriology. 196:1532-1539
The ATP-dependent transporter gene abcA in Staphylococcus aureus confers resistance to hydrophobic β-lactams. In strain ISP794, abcA is regulated by the transcriptional regulators MgrA and NorG and shares a 420-nucleotide intercistronic region with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be8d5dfa74bccdc6ad2b284467177988
https://doi.org/10.1128/jb.01406-13
https://doi.org/10.1128/jb.01406-13
Publikováno v:
Infection and immunity. 85(2)
We previously reported that the Tet38 efflux pump is involved in internalization of Staphylococcus aureus by A549 lung epithelial cells. A lack of tet38 reduced bacterial uptake by A549 cells to 36% of that of the parental strain RN6390. Using invasi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08b6e8782b76ed449fbc8708b8ef4d50
https://pubmed.ncbi.nlm.nih.gov/27956597
https://pubmed.ncbi.nlm.nih.gov/27956597