Tetra- versus Pentavalent Inhibitors of Cholera Toxin

Autor: Fu, O, Pukin, AV, Quarles van Ufford, HC, Branson, TR, Thies-Weesie, DME, Turnbull, WB, Visser, GM, Pieters, RJ

The five B-subunits (CTB5) of the Vibrio cholerae (cholera) toxin can bind to the intestinal cell surface so the entire AB5 toxin can enter the cell. Simultaneous binding can occur on more than one of the monosialotetrahexosylganglioside (GM1) units

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::4b98181796d8e65399093295bfecf07e
https://dspace.library.uu.nl/handle/1874/322956

An insight into the antibiofilm properties of Costa Rican stingless bee honeys.

Autor: Zamora LG; Microbiologist, Coordinator of the Microbiology and Medicinal Chemistry Program, Medicinal Chemistry and Chemical Biology Program, Department of Pharmaceutical Sciences, Faculty of Science, Utrecht University. David de Wiedgebouw, P. O. B. 80082, 3508 TB Utrecht, The Netherlands; Centro de Investigaciones Apícolas Tropicales, Universidad Nacional. P. O. Box 475-3000 Heredia, Costa Rica., Beukelman CJ; Associate Professor, Medicinal Chemistry and Chemical Biology Program, Department of Pharmaceutical Sciences, Faculty of Science, Utrecht University. David de Wiedgebouw, P. O. B. 80082, 3508 TB Utrecht, The Netherlands., van den Berg AJ; Associate Professor, Medicinal Chemistry and Chemical Biology Program, Department of Pharmaceutical Sciences, Faculty of Science, Utrecht University. David de Wiedgebouw, P. O. B. 80082, 3508 TB Utrecht, The Netherlands., Aerts PC; Senior Technician, Medical Microbiology, University Medical Center Utrecht, P. O. B. 85500, 3508 GA Utrecht, The Netherlands., Quarles van Ufford HC; Research and Education Assistant, Medicinal Chemistry and Chemical Biology Program, Department of Pharmaceutical Sciences, Faculty of Science, Utrecht University. David de Wiedgebouw, P. O. B. 80082, 3508 TB Utrecht, The Netherlands., Nijland R; Assistant Professor, Coordinator of the Bacteriology Group, Medical Microbiology, University Medical Center Utrecht, P. O. B. 85500, 3508 GA Utrecht, The Netherlands; Laboratory of Phytopatology, Wageningen University. P. O. Box 16, 6700 A A Wageningen, The Netherlands., Arias ML; Coordinator of the Laboratory of Food Microbiology, Facultad de Microbiología, Universidad de Costa Rica. P. O. Box 2060-1000 San José, Costa Rica.

Publikováno v: Journal of wound care [J Wound Care] 2017 Apr 02; Vol. 26 (4), pp. 168-177.

Thiourea-based spacers in potent divalent inhibitors of Pseudomonas aeruginosa virulence lectin LecA.

Autor: Pukin AV; Department of Medicinal Chemistry & Chemical Biology, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, PO Box 80082, 3508 TB, Utrecht, The Netherlands. R.J.Pieters@uu.nl., Brouwer AJ, Koomen L, Quarles van Ufford HC, Kemmink J, de Mol NJ, Pieters RJ

Publikováno v: Organic & biomolecular chemistry [Org Biomol Chem] 2015 Nov 28; Vol. 13 (44), pp. 10923-8. Date of Electronic Publication: 2015 Sep 15.

A proteinaceous fraction of wheat bran may interfere in the attachment of enterotoxigenic E. coli K88 (F4+) to porcine epithelial cells.

Autor: González-Ortiz G; Servei de Nutrició i Benestar Animal (SNiBA), Departament de Ciència Animal i dels Aliments, Universitat Autònoma de Barcelona, Barcelona, Spain., Bronsoms S; Servei de Proteòmica i Biologia Estructural, Universitat Autònoma de Barcelona, Mòdul B Parc de Recerca, Barcelona, Spain., Quarles Van Ufford HC; Department of Medicinal Chemistry & Chemical Biology, Utrecht University, Utrecht, The Netherlands., Halkes SB; Department of Medicinal Chemistry & Chemical Biology, Utrecht University, Utrecht, The Netherlands., Virkola R; Department of Biosciences, General Microbiology, University of Helsinki, Helsinki, Finland., Liskamp RM; Department of Medicinal Chemistry & Chemical Biology, Utrecht University, Utrecht, The Netherlands., Beukelman CJ; Department of Medicinal Chemistry & Chemical Biology, Utrecht University, Utrecht, The Netherlands., Pieters RJ; Department of Medicinal Chemistry & Chemical Biology, Utrecht University, Utrecht, The Netherlands., Pérez JF; Servei de Nutrició i Benestar Animal (SNiBA), Departament de Ciència Animal i dels Aliments, Universitat Autònoma de Barcelona, Barcelona, Spain., Martín-Orúe SM; Servei de Nutrició i Benestar Animal (SNiBA), Departament de Ciència Animal i dels Aliments, Universitat Autònoma de Barcelona, Barcelona, Spain.

Publikováno v: PloS one [PLoS One] 2014 Aug 13; Vol. 9 (8), pp. e104258. Date of Electronic Publication: 2014 Aug 13 (Print Publication: 2014).

New properties of wheat bran: anti-biofilm activity and interference with bacteria quorum-sensing systems.

Autor: González-Ortiz G; Servei de Nutrició i Benestar Animal (SNiBA), Departament de Ciència Animal i dels Aliments, Universitat Autònoma de Barcelona (UAB), 08193 Bellaterra, Barcelona, Spain., Quarles Van Ufford HC, Halkes SB, Cerdà-Cuéllar M, Beukelman CJ, Pieters RJ, Liskamp RM, Pérez JF, Martín-Orue SM

Publikováno v: Environmental microbiology [Environ Microbiol] 2014 May; Vol. 16 (5), pp. 1346-53. Date of Electronic Publication: 2014 Apr 04.