Výsledky vyhledávání - "Quaovi H Sodji"

Akademický článek

Durability of response in metastatic melanoma patients after combined treatment with radiation therapy and ipilimumab

Autor: Quaovi H Sodji, Paulina M Gutkin, Susan M Swetter, Sunil A Reddy, Susan M Hiniker, Susan J Knox

Publikováno v: Melanoma Management, Vol 7, Iss 1 (2020)

Aim: We previously reported a prospective trial evaluating the safety and efficacy of combining ipilimumab and radiation therapy in patients with metastatic melanoma. Herein, we provide a long-term update on patients with complete response (CR) or pa

Externí odkaz: https://doaj.org/article/b0a08ad854ea4a80888fbd8122d6b6ff

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Akademický článek

Metabolic priming of GD2 TRAC-CAR T cells during manufacturing promotes memory phenotypes while enhancing persistence

Autor: Dan Cappabianca, Dan Pham, Matthew H. Forsberg, Madison Bugel, Anna Tommasi, Anthony Lauer, Jolanta Vidugiriene, Brookelyn Hrdlicka, Alexandria McHale, Quaovi H. Sodji, Melissa C. Skala, Christian M. Capitini, Krishanu Saha

Publikováno v: Molecular Therapy: Methods & Clinical Development, Vol 32, Iss 2, Pp 101249- (2024)

Manufacturing chimeric antigen receptor (CAR) T cell therapies is complex, with limited understanding of how medium composition impacts T cell phenotypes. CRISPR-Cas9 ribonucleoproteins can precisely insert a CAR sequence while disrupting the endogen

Externí odkaz: https://doaj.org/article/74f39a1628344c7f928bd6f3024b4800

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Akademický článek

Immunological effects of radiopharmaceutical therapy

Autor: Amanda G. Shea, Malick Bio Idrissou, Ana Isabel Torres, Tessa Chen, Reiner Hernandez, Zachary S. Morris, Quaovi H. Sodji

Publikováno v: Frontiers in Nuclear Medicine, Vol 4 (2024)

Radiation therapy (RT) is a pillar of cancer therapy used by more than half of all cancer patients. Clinically, RT is mostly delivered as external beam radiation therapy (EBRT). However, the scope of EBRT is limited in the metastatic setting, where a

Externí odkaz: https://doaj.org/article/4e5793cbbf8a4645b5099ead59e87c79

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Data from C3aR Signaling Inhibits NK-cell Infiltration into the Tumor Microenvironment in Mouse Models

Autor: Amato J. Giaccia, Edward E. Graves, Quaovi H. Sodji, Yu Xu, Caiyun G. Li, Saravanan Nandagopal

Many solid tumors have low levels of cytotoxic CD56dim natural killer (NK) cells, suggesting that CD56dim NK-cell exclusion from the tumor microenvironment (TME) contributes to the decreased response rate of immunotherapy. Complement component 3a (C3

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aed99cd4e11eff4c38a3bffcb5d44b6e
https://doi.org/10.1158/2326-6066.c.6550611.v1

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Data from The Combination of Radiotherapy and Complement C3a Inhibition Potentiates Natural Killer cell Functions Against Pancreatic Cancer

Autor: Amato J. Giaccia, Quynh-Thu Le, Daniel T. Chang, Monica M. Olcina, Caiyun G. Li, Michael S. Binkley, Deana Colburg, Rie von Eyben, Vignesh Viswanathan, Dhanya K. Nambiar, Quaovi H. Sodji

Pancreatic cancer is one of the deadliest cancers, against which current immunotherapy strategies are not effective. Herein, we analyzed the immune cell composition of the tumor microenvironment of pancreatic cancer samples in The Cancer Genome Atlas

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::817fa32a8cee2e86b420d75e48cc0531
https://doi.org/10.1158/2767-9764.c.6550977

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