Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Quanzhong, Chang"'
Publikováno v:
Neurosignals, Vol 24, Iss 1, Pp 40-47 (2016)
Background/Aims: Alzheimer‘s disease (AD) is characterized by accumulation of β-amyloid (Aβ), However, the mechanism of how Aβ affects neuronal cell death remains elusive. The balance of pro- and anti-apoptotic Bcl-2 family proteins (e.g., Bcl-2
Externí odkaz:
https://doaj.org/article/f31c0a8ec7bc4101902eaf3da497d16b
Publikováno v:
Journal of Neuroscience Research. 95:2483-2492
Currently antidepressants take several weeks to be effective, which is one of the main reasons why patients with depression quit therapy. In the present study, we examine the acute and subacute effects of soluble epoxide hydolase (sEH) inhibitor (sEH
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9d5e73e9831c99ab0c2122c6ccbda1e4
https://doi.org/10.1002/jnr.24080
https://doi.org/10.1002/jnr.24080
Publikováno v:
Journal of molecular neuroscience : MN. 67(3)
High level of corticosterone (CORT) is toxic to neurons and plays an important role in depression-like behavior and chronic stress. Our previous study showed that TPPU, a soluble epoxide hydrolase (sEH) inhibitor (sEHI), induces an antidepressant eff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6340d807a8ad0f3a2d30b9eb1764665
https://pubmed.ncbi.nlm.nih.gov/30644034
https://pubmed.ncbi.nlm.nih.gov/30644034
Publikováno v:
Journal of neuroscience research. 95(12)
Currently antidepressants take several weeks to be effective, which is one of the main reasons why patients with depression quit therapy. In the present study, we examine the acute and subacute effects of soluble epoxide hydolase (sEH) inhibitor (sEH
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1060d454f38a989725deea44586cb778
https://pubmed.ncbi.nlm.nih.gov/28699310
https://pubmed.ncbi.nlm.nih.gov/28699310
Publikováno v:
Neurosignals, Vol 24, Iss 1, Pp 40-47 (2016)
Background/Aims: Alzheimer‘s disease (AD) is characterized by accumulation of β-amyloid (Aβ), However, the mechanism of how Aβ affects neuronal cell death remains elusive. The balance of pro- and anti-apoptotic Bcl-2 family proteins (e.g., Bcl-2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30fc079568b5dcd86df22b94c3722b3f
https://pubmed.ncbi.nlm.nih.gov/27318974
https://pubmed.ncbi.nlm.nih.gov/27318974
Publikováno v:
Brain research. 1644
Cerebral ischemia induces delayed, selective neuronal death in the CA1 region of the hippocampus. The underlying molecular mechanisms remain unclear, but it is known that apoptosis is involved in this process. Chloride efflux has been implicated in t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eeb4bf3bf17842375b9fefefcf6ad640
https://pubmed.ncbi.nlm.nih.gov/27181516
https://pubmed.ncbi.nlm.nih.gov/27181516
Autor:
Lijuan, Xu, Shuling, Zhang, Hongling, Fan, Zhichao, Zhong, Xi, Li, Xiaoxiao, Jin, Quanzhong, Chang
Publikováno v:
Neural Regeneration Research
Over-production of nitric oxide is pathogenic for neuronal apoptosis around the ischemic area fol-lowing ischemic brain injury. In this study, an apoptotic model in rat hippocampal neurons was tablished by 0.5 mmol/L 3-morpholinosyndnomine (SIN-1), a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::dc6fd1f64c1ffc119ec2851cb8b44914
https://pubmed.ncbi.nlm.nih.gov/25206625
https://pubmed.ncbi.nlm.nih.gov/25206625
Rapid elevation of calcium concentration in cultured dorsal spinal cord astrocytes by corticosterone
Autor:
Min Li, Hong Tian, Zhi Xiao, Chen Yuanshou, Xiaohong Liu, Huan Jin, Junwei Zeng, Quanzhong Chang
Publikováno v:
Neurochemical research. 38(2)
In addition to the classic genomic effects, increasing evidence suggests that GC can generate multiple rapid effects on many tissues and cells through nongenomic pathway. In the present study, the effects of corticosterone (CORT) on the intracellular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::495dc1ed01bff3a81bfedf0e05135b54
https://pubmed.ncbi.nlm.nih.gov/23179589
https://pubmed.ncbi.nlm.nih.gov/23179589
Autor:
Jinbao, Yin, Lijuan, Xu, Shuling, Zhang, Yuanyin, Zheng, Zhichao, Zhong, Hongling, Fan, Xi, Li, Quanzhong, Chang
Publikováno v:
Neural Regeneration Research
Apoptosis in cultured rat hippocampal neurons was induced using the nitric oxide donor 3-morpholinosydnonimine, and cells were treated with the chloride channel blocker, 4,4-diisothiocyanatostilbene-2,2′-disulfonic acid. Results showed that the sur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::68e177b6432bf9e9ac0881e2299dc3cc
https://pubmed.ncbi.nlm.nih.gov/25206481
https://pubmed.ncbi.nlm.nih.gov/25206481
Autor:
Yuanyin, Zheng, Lijuan, Xu, Jinbao, Yin, Zhichao, Zhong, Hongling, Fan, Xi, Li, Quanzhong, Chang
Publikováno v:
Neural Regeneration Research
Minocylcine, a tetracycline derivate, has been shown to cross the blood-brain barrier and enter the central nervous system. In this study, cerebral ischemia-reperfusion injury models were established using the suture method, and minocycline was immed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5f7e4a9362746977fbdddad5e97af4a8
https://pubmed.ncbi.nlm.nih.gov/25206381
https://pubmed.ncbi.nlm.nih.gov/25206381