Zobrazeno 1 - 10
of 76
pro vyhledávání: '"Quanyan Liu"'
Publikováno v:
BMC Gastroenterology, Vol 24, Iss 1, Pp 1-12 (2024)
Abstract Background Although gut microbiota and serum metabolite composition have been observed to be altered in patients with non-alcoholic fatty liver disease (NAFLD), previous observational studies have demonstrated inconsistent results. As this m
Externí odkaz:
https://doaj.org/article/9540cb07194e47dc9dcc71eea7ce016d
Autor:
Xiaojie Yan, Xinxin Yuan, Jianke Lv, Bing Zhang, Yongle Huang, Qianqian Li, Jinfeng Ma, Yanran Li, Xiaolu Wang, Yao Li, Ying Yu, Quanyan Liu, Tong Liu, Wenyi Mi, Cheng Dong
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract SAP05, a secreted effector by the obligate parasitic bacteria phytoplasma, bridges host SPL and GATA transcription factors (TFs) to the 26 S proteasome subunit RPN10 for ubiquitination-independent degradation. Here, we report the crystal str
Externí odkaz:
https://doaj.org/article/831369381f344b739244bd6ab5b9fa09
Autor:
Xiaolu Wang, Yao Li, Xiaojie Yan, Qing Yang, Bing Zhang, Ying Zhang, Xinxin Yuan, Chenhao Jiang, Dongxing Chen, Quanyan Liu, Tong Liu, Wenyi Mi, Ying Yu, Cheng Dong
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Abstract The ribosome-associated quality-control (RQC) pathway degrades aberrant nascent polypeptides arising from ribosome stalling during translation. In mammals, the E3 ligase Pirh2 mediates the degradation of aberrant nascent polypeptides by targ
Externí odkaz:
https://doaj.org/article/9d7dc35ef8c044d99d5b5ea51be43ee9
Publikováno v:
Genes and Diseases, Vol 9, Iss 4, Pp 845-848 (2022)
Externí odkaz:
https://doaj.org/article/b1096cbc30934ec38edb289c91ac17a8
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Intraductal papillary neoplasm of the bile duct (IPNB) is a rare bile duct tumor characterized by intraductal papillary or villous neoplasms covered by neoplastic epithelium with fine fibrovascular stalks in the dilated bile ducts (1). Its true etiol
Externí odkaz:
https://doaj.org/article/a8eb4f6654e24a148052d2c1bfcb9f86
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 38, Iss 1, Pp 1-13 (2019)
Abstract Background Hepatocellular carcinoma (HCC) still remains a dominating medical challenge in early diagnosis and clinical therapy. Centromere protein M (CENPM) has been proved to be over-expressed in HCC tissues, but carcinogenic mechanism of C
Externí odkaz:
https://doaj.org/article/6c7b1f7a01d4465e84bbb00cec8926c6
Publikováno v:
Frontiers in Surgery, Vol 8 (2021)
Background: Neuroendocrine tumors are heterogeneous malignancies that originate from the neuroendocrine system. Previous studies show that this cancer type mainly localizes in the gastrointestinal tract and often metastasizes to the liver. Primary li
Externí odkaz:
https://doaj.org/article/87af7abc8b1748448459b786a1feeb3c
Autor:
Yang Gu, Jun Li, Deliang Guo, Baiyang Chen, Pengpeng Liu, Yusha Xiao, Kang Yang, Zhisu Liu, Quanyan Liu
Publikováno v:
Frontiers in Genetics, Vol 11 (2020)
Hepatocellular carcinoma (HCC) remains hard to diagnose early and cure due to a lack of accurate biomarkers and effective treatments. Hence, it is necessary to explore the tumorigenesis and tumor progression of HCC to discover new biomarkers for clin
Externí odkaz:
https://doaj.org/article/3001f20ce845492bb737409dcc2aa597
Publikováno v:
Gastroenterology Research and Practice, Vol 2016 (2016)
Aims. To understand the feasibility and efficacy of treatment with SAMe in patients with hepatitis B-related HCC with different Barcelona Clinic Liver Cancer (BCLC) stages. Methods. We retrospectively enrolled 697 patients with BCLC early-stage (stag
Externí odkaz:
https://doaj.org/article/6d40992836dd48fda6e52f72e6f61c90
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0122124 (2015)
It has been well established that S-adenosyl-L-methionine (SAMe) is the principal methyl donor in methyltransferase reactions and that SAMe supplementation restores hepatic glutathione (GSH) deposits and attenuates liver injury. However, the effectiv
Externí odkaz:
https://doaj.org/article/f1b460e46ac44b9480678530ac3a72cc