Zobrazeno 1 - 10
of 222
pro vyhledávání: '"Quanxing Ni"'
Autor:
Chen Liu, Shengming Deng, Zhiwen Xiao, Renquan Lu, He Cheng, Jingjing Feng, Xuxia Shen, Quanxing Ni, Weiding Wu, Xianjun Yu, Guopei Luo
Publikováno v:
Discover Oncology, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Background Carbohydrate antigen 19–9 (CA19-9) is the most widely used biomarker for pancreatic cancer. Since CA19-9 closely correlates with patient outcome and tumor stage in pancreatic cancer, the deciphering of CA19-9 biosynthesis provid
Externí odkaz:
https://doaj.org/article/5eaa316c0eed46148d8c9aa04d2bb666
Autor:
Yitao Gong, Yunzhen Qian, Guopei Luo, Yu Liu, Ruijie Wang, Shengming Deng, He Cheng, Kaizhou Jin, Quanxing Ni, Xianjun Yu, Weiding Wu, Chen Liu
Publikováno v:
World Journal of Surgical Oncology, Vol 19, Iss 1, Pp 1-8 (2021)
Abstract Background Glutamine-fructose-6-phosphate transaminase 1 (GFPT1) is the first rate-limiting enzyme of the hexosamine biosynthesis pathway (HBP), which plays a pivotal role in the progression of pancreatic ductal adenocarcinoma (PDAC). Theref
Externí odkaz:
https://doaj.org/article/97b2d54f28c84ea58371efd07c86e3b6
Autor:
Yunzhen Qian, Yitao Gong, Zhiyao Fan, Guopei Luo, Qiuyi Huang, Shengming Deng, He Cheng, Kaizhou Jin, Quanxing Ni, Xianjun Yu, Chen Liu
Publikováno v:
Journal of Hematology & Oncology, Vol 13, Iss 1, Pp 1-20 (2020)
Abstract Pancreatic ductal adenocarcinoma (PDAC) is a malignancy characterized by a poor prognosis and high mortality rate. Genetic mutations and altered molecular pathways serve as targets in precise therapy. Using next-generation sequencing (NGS),
Externí odkaz:
https://doaj.org/article/5010a92b482e48ba911dd2d523f4cf37
Autor:
Zhiyao Fan, He Cheng, Kaizhou Jin, Yitao Gong, Qiuyi Huang, Jin Xu, Quanxing Ni, Xianjun Yu, Chen Liu, Guopei Luo
Publikováno v:
World Journal of Surgical Oncology, Vol 17, Iss 1, Pp 1-8 (2019)
Abstract Background Both the 7th and 8th editions of the American Joint Committee on Cancer (AJCC) staging systems have been introduced for pancreatic adenocarcinoma. However, the applicability of these classifications for invasive intraductal papill
Externí odkaz:
https://doaj.org/article/973196a123634d8faaafc1db77eeb53e
Autor:
Yitao Gong, Zhiyao Fan, Guopei Luo, Chao Yang, Qiuyi Huang, Kun Fan, He Cheng, Kaizhou Jin, Quanxing Ni, Xianjun Yu, Chen Liu
Publikováno v:
Molecular Cancer, Vol 18, Iss 1, Pp 1-17 (2019)
Abstract Apoptosis resistance is to a large extent a major obstacle leading to chemotherapy failure during cancer treatment. Bypassing the apoptotic pathway to induce cancer cell death is considered to be a promising approach to overcoming this probl
Externí odkaz:
https://doaj.org/article/ac73ba75946446469c7e217973f8aa35
Autor:
Yi Qin, Qiangsheng Hu, Jin Xu, Shunrong Ji, Weixing Dai, Wensheng Liu, Wenyan Xu, Qiqing Sun, Zheng Zhang, Quanxing Ni, Bo Zhang, Xianjun Yu, Xiaowu Xu
Publikováno v:
Cell Communication and Signaling, Vol 17, Iss 1, Pp 1-15 (2019)
Abstract Background The epigenetic factor protein arginine methyltransferase 5 (PRMT5) has been reported to play vital roles in a wide range of cellular processes, such as gene transcription, genomic organization, differentiation and cell cycle contr
Externí odkaz:
https://doaj.org/article/96f70f9a165949abab417426d2493246
Autor:
Shuo Li, Huaxiang Xu, Chuntao Wu, Wenquan Wang, Wei Jin, Heli Gao, Hao Li, Shirong Zhang, Jinzhi Xu, Wuhu Zhang, Shuaishuai Xu, Tianjiao Li, Quanxing Ni, Xianjun Yu, Liang Liu
Publikováno v:
Cancer Medicine, Vol 8, Iss 2, Pp 572-584 (2019)
Abstract Pancreatic ductal adenocarcinoma (PDAC) is a devastating malignancy with poor prognosis. Many preoperative biomarkers can predict postoperative survival of PDAC patients. In this study, we created a novel ratio index based on preoperative li
Externí odkaz:
https://doaj.org/article/03a492ba76094db193be227f3f7e4ae9
Autor:
Chen Liu MD, PhD, He Cheng MD, Kaizhou Jin MD, PhD, Zhiyao Fan MD, Yitao Gong MD, Yunzhen Qian MD, Shengming Deng MD, Qiuyi Huang MD, Quanxing Ni MD, Xianjun Yu MD, PhD, Guopei Luo MD, PhD
Publikováno v:
Cancer Control, Vol 27 (2020)
Lymphatic metastasis is a major determinant of the outcome of resected pancreatic cancer. Gemcitabine-based adjuvant chemotherapy can improve the outcome of resected pancreatic cancer. However, the efficacy of gemcitabine against pancreatic cancer st
Externí odkaz:
https://doaj.org/article/f000c65ebf8241d8bdbd31f43f6f96bc
Autor:
Meng Guo, Guopei Luo, Kaizhou Jin, Jiang Long, He Cheng, Yu Lu, Zhengshi Wang, Chao Yang, Jin Xu, Quanxing Ni, Xianjun Yu, Chen Liu
Publikováno v:
International Journal of Molecular Sciences, Vol 18, Iss 1, p 81 (2017)
Solid pseudopapillary tumor of the pancreas (SPT) is a rare pancreatic disease with a unique clinical manifestation. Although CTNNB1 gene mutations had been universally reported, genetic variation profiles of SPT are largely unidentified. We conducte
Externí odkaz:
https://doaj.org/article/71e99e6ef2764cc5a790e41a65ef0fab
Autor:
Meng Guo, Guopei Luo, Chen Liu, He Cheng, Yu Lu, Kaizhou Jin, Zuqiang Liu, Jiang Long, Liang Liu, Jin Xu, Dan Huang, Quanxing Ni, Xianjun Yu
Publikováno v:
International Journal of Molecular Sciences, Vol 17, Iss 7, p 1090 (2016)
The data regarding the prognostic significance of EGFR (epidermal growth factor receptor) expression and adjuvant therapy in patients with resected pancreatic cancer are insufficient. We retrospectively investigated EGFR status in 357 resected PDAC (
Externí odkaz:
https://doaj.org/article/8c9431275884457292ba5747a078e1ee