Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Quanxiang Xian"'
Autor:
Xuandi Hou, Jianing Jing, Yizhou Jiang, Xiaohui Huang, Quanxiang Xian, Ting Lei, Jiejun Zhu, Kin Fung Wong, Xinyi Zhao, Min Su, Danni Li, Langzhou Liu, Zhihai Qiu, Lei Sun
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Ultrasound is an acoustic wave which can noninvasively penetrate the skull to deep brain regions, enabling neuromodulation. However, conventional ultrasound’s spatial resolution is diffraction-limited and low-precision. Here, we report aco
Externí odkaz:
https://doaj.org/article/bd8873157a9743d2b422bb48371f4024
Autor:
Tianyi Liu, Mi Hyun Choi, Jiejun Zhu, Tingting Zhu, Jin Yang, Na Li, Zihao Chen, Quanxiang Xian, Xuandi Hou, Dongmin He, Jinghui Guo, Chunlong Fei, Lei Sun, Zhihai Qiu
Publikováno v:
Brain Stimulation, Vol 15, Iss 5, Pp 1308-1317 (2022)
Sonogenetics refers to the use of genetically encoded, ultrasound-responsive mediators for noninvasive and selective control of neural activity. It is a promising tool for studying neural circuits. However, due to its infancy, basic studies and devel
Externí odkaz:
https://doaj.org/article/b70badd21c3c4a6ea18ec88895507b89
Autor:
Jinghui Guo, Yong Wu, Zhiyong Gong, Xixi Chen, Fei Cao, Shashwati Kala, Zhihai Qiu, Xinyi Zhao, Jun‐jiang Chen, Dongming He, Taiheng Chen, Rui Zeng, Jiejun Zhu, Kin Fung Wong, Suresh Murugappan, Ting Zhu, Quanxiang Xian, Xuandi Hou, Ye Chun Ruan, Baojun Li, Yu Chao Li, Yao Zhang, Lei Sun
Publikováno v:
Advanced Science, Vol 9, Iss 12, Pp n/a-n/a (2022)
Abstract Optogenetics has become a widely used technique in neuroscience research, capable of controlling neuronal activity with high spatiotemporal precision and cell‐type specificity. Expressing exogenous opsins in the selected cells can induce n
Externí odkaz:
https://doaj.org/article/5eb36057b9c545edbd72b86bb9c8ebc0
Autor:
Zhihai Qiu, Jinghui Guo, Shashwati Kala, Jiejun Zhu, Quanxiang Xian, Weibao Qiu, Guofeng Li, Ting Zhu, Long Meng, Rui Zhang, Hsiao Chang Chan, Hairong Zheng, Lei Sun
Publikováno v:
iScience, Vol 21, Iss , Pp 448-457 (2019)
Summary: Ultrasound brain stimulation is a promising modality for probing brain function and treating brain disease non-invasively and with high spatiotemporal resolution. However, the mechanism underlying its effects remains unclear. Here, we examin
Externí odkaz:
https://doaj.org/article/a7ef390ef1804d62b80cd8c1fd247ea5
Autor:
Xuandi Hou, Zhihai Qiu, Quanxiang Xian, Shashwati Kala, Jianing Jing, Kin Fung Wong, Jiejun Zhu, Jinghui Guo, Ting Zhu, Minyi Yang, Lei Sun
Publikováno v:
Advanced Science, Vol 8, Iss 21, Pp n/a-n/a (2021)
Abstract Ultrasound is a promising new modality for non‐invasive neuromodulation. Applied transcranially, it can be focused down to the millimeter or centimeter range. The ability to improve the treatment's spatial resolution to a targeted brain re
Externí odkaz:
https://doaj.org/article/853cee1e154f4295873f6d58c62b676d
Autor:
Quanxiang Xian, Zhihai Qiu, Shashwati Kala, Jinghui Guo, Jiejun Zhu, Kin Fung Wong, Sean Shu Yi Guo, Ting Zhu, Xuandi Hou, Lei Sun
Publikováno v:
STAR Protocols, Vol 2, Iss 2, Pp 100393- (2021)
Summary: Manipulating specific neural activity by targeted ultrasound intervention is a powerful method to gain causal insight into brain functions and treat brain disorders. The technique of sonogenetics enables controlling of cells that are genetic
Externí odkaz:
https://doaj.org/article/923e389ce4e047a79c6aa6f494fca611
Autor:
Quanxiang Xian, Zhihai Qiu, Suresh Murugappan, Shashwati Kala, Kin Fung Wong, Danni Li, Guofeng Li, Yizhou Jiang, Yong Wu, Min Su, Xuandi Hou, Jiejun Zhu, Jinghui Guo, Weibao Qiu, Lei Sun
Publikováno v:
Proceedings of the National Academy of Sciences. 120
Noninvasive control of neuronal activity in the deep brain can be illuminating for probing brain function and treating dysfunctions. Here, we present a sonogenetic approach for controlling distinct mouse behavior with circuit specificity and subsecon
Autor:
Jiejun Zhu, Quanxiang Xian, Xuandi Hou, Kin Fung Wong, Tingting Zhu, Zihao Chen, Dongming He, Shashwati Kala, Suresh Murugappan, Jianing Jing, Yong Wu, Xinyi Zhao, Danni Li, Jinghui Guo, Zhihai Qiu, Lei Sun
Publikováno v:
Proceedings of the National Academy of Sciences. 120
Transcranial low-intensity ultrasound is a promising neuromodulation modality, with the advantages of noninvasiveness, deep penetration, and high spatiotemporal accuracy. However, the underlying biological mechanism of ultrasonic neuromodulation rema
Autor:
Quanxiang Xian, Zhihai Qiu, Shashwati Kala, Kin Fung Wong, Suresh Murugappan, Yong Wu, Xuandi Hou, Jiejun Zhu, Jinghui Guo, Lei Sun
Sonogenetics uses heterologously-expressed proteins to sensitize neurons to ultrasound, enabling selective, non-invasive, and deep brain stimulation. However, its ability to modulate specific circuits or induce behavioral changes remains to be studie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cce88ec9634c3887909bdd12171227ed
https://doi.org/10.1101/2021.11.06.467579
https://doi.org/10.1101/2021.11.06.467579
Autor:
Jinghui Guo, Minyi Yang, Kin Fung Wong, Lei Sun, Ting Zhu, Jianing Jing, Quanxiang Xian, Shashwati Kala, Xuandi Hou, Zhihai Qiu, Jiejun Zhu
Publikováno v:
Advanced Science
Advanced Science, Vol 8, Iss 21, Pp n/a-n/a (2021)
Advanced Science, Vol 8, Iss 21, Pp n/a-n/a (2021)
Ultrasound is a promising new modality for non‐invasive neuromodulation. Applied transcranially, it can be focused down to the millimeter or centimeter range. The ability to improve the treatment's spatial resolution to a targeted brain region coul