Zobrazeno 1 - 10
of 87 732
pro vyhledávání: '"Quantitative Biology"'
Through experimental studies, many details of the pathway of integrin $\alpha_{\rm IIb}\beta_3$ activation by ADP during the platelet aggregation process have been mapped out. ADP binds to two separate G protein coupled receptors on platelet surfaces
Externí odkaz:
http://arxiv.org/abs/2410.13015
Accurate prediction of RNA properties, such as stability and interactions, is crucial for advancing our understanding of biological processes and developing RNA-based therapeutics. RNA structures can be represented as 1D sequences, 2D topological gra
Externí odkaz:
http://arxiv.org/abs/2410.11933
Autor:
Shen, Rui Sherry, Osmanlıoğlu, Yusuf, Parker, Drew, Aunapu, Darien, Yerys, Benjamin E., Tunç, Birkan, Verma, Ragini
Many neurodevelopmental disorders can be understood as divergent patterns of neural interactions during brain development. Advances in neuroimaging have illuminated these patterns by modeling the brain as a network structure using diffution MRI tract
Externí odkaz:
http://arxiv.org/abs/2410.11064
Fine-tuning the ESM2 protein language model to understand the functional impact of missense variants
Autor:
Saadat, Ali, Fellay, Jacques
Elucidating the functional effect of missense variants is of crucial importance, yet challenging. To understand the impact of such variants, we fine-tuned the ESM2 protein language model to classify 20 protein features at amino acid resolution. We us
Externí odkaz:
http://arxiv.org/abs/2410.10919
Autor:
Kleidon, Axel
Life is a planetary feature that depends on its environment, but it has also strongly shaped the physical conditions on Earth, having created conditions highly suitable for a productive biosphere. Clearly, the second law of thermodynamics must apply
Externí odkaz:
http://arxiv.org/abs/2410.10213
Oxidative stress is a fundamental stimulus to which eukaryotic cells respond via many channels. Among these channels are both protein systems that process oxidative stress, such as the 2-Cys peroxiredoxin-thioredoxin system (PTRS), as well as changes
Externí odkaz:
http://arxiv.org/abs/2410.10145
Structuring data analysis projects, that is, defining the layout of files and folders needed to analyze data using existing tools and novel code, largely follows personal preferences. In this work, we look at the structure of several data analysis pr
Externí odkaz:
http://arxiv.org/abs/2410.10513
Autor:
Johnson, Connah G. M., Johnson, Zachary, Mackey, Liam S., Li, Xiaolu, Sadler, Natalie C., Zhang, Tong, Qian, Wei-Jun, Bohutskyi, Pavlo, Feng, Song, Cheung, Margaret S.
We develop a systems approach based on an energy-landscape concept to differentiate interactions involving redox activities and conformational changes of proteins and nucleic acids interactions in multi-layered protein-DNA regulatory networks under l
Externí odkaz:
http://arxiv.org/abs/2410.09346
Autor:
Kapila, Sundeep, Nair, Pradeep R.
Exocytosis is a fundamental process related to the information exchange in the nervous and endocrine system. Among the various techniques, vesicle impact electrochemical cytometry (VIEC) has emerged as an effective method to mimic the exocytosis proc
Externí odkaz:
http://arxiv.org/abs/2410.06631
The sugar concentration of nectar is a key metric for describing nectar composition and a major factor influencing pollinator visitation to flowers. Across pollination biology research there are multiple approaches in use for describing nectar sugar
Externí odkaz:
http://arxiv.org/abs/2410.05855