Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Quanri Jin"'
Autor:
Hye-Jin Boo, Hye-Young Min, Hyun-Ji Jang, Hye Jeong Yun, John Kendal Smith, Quanri Jin, Hyo-Jong Lee, Diane Liu, Hee-Seok Kweon, Carmen Behrens, J. Jack Lee, Ignacio I. Wistuba, Euni Lee, Waun Ki Hong, Ho-Young Lee
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-16 (2016)
The binding of tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) to nicotinic acetylcholine receptors (nAChRs) induces calcium signalling. Here the authors show that NKK-induced calcium influx in airway epithelial cells
Externí odkaz:
https://doaj.org/article/b677a8e4f78945a8ba09e04a707207e1
Autor:
Ho-Young Lee, Ignacio I. Wistuba, Waun Ki Hong, Scott M. Lippman, J. Jack Lee, York E. Miller, Ludmila Prudkin, Carmen Behrens, Lei Feng, Dong Hoon Lee, Youn Joo Yang, Edward S. Kim, Seung-Hyun Oh, Quanri Jin, Woo-Young Kim
Insulin-like growth factor (IGF)-I receptor (IGF-IR) signaling has been implicated in several human neoplasms. However, the role of serum levels of IGFs in lung cancer risk is controversial. We assessed the role of tissue-derived IGFs in lung carcino
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::190285a44883fa48c03ba32d90c835fe
https://doi.org/10.1158/0008-5472.c.6499053
https://doi.org/10.1158/0008-5472.c.6499053
Autor:
Ho-Young Lee, Ignacio I. Wistuba, Waun Ki Hong, Scott M. Lippman, J. Jack Lee, York E. Miller, Ludmila Prudkin, Carmen Behrens, Lei Feng, Dong Hoon Lee, Youn Joo Yang, Edward S. Kim, Seung-Hyun Oh, Quanri Jin, Woo-Young Kim
Supplementary Figures 1-6, Tables 1-2 from Elevated Epithelial Insulin-like Growth Factor Expression Is a Risk Factor for Lung Cancer Development
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e53b16d8e255007058179d7ea84a447
https://doi.org/10.1158/0008-5472.22378929.v1
https://doi.org/10.1158/0008-5472.22378929.v1
Autor:
Young Mi Whang, Quanri Jin, Ho-Young Lee, Yeul Hong Kim, John Kendal Smith, Hye-Young Min, Su Jung Hwang, Hyo Jong Lee, Woo-Young Kim
Publikováno v:
Carcinogenesis. 35:2232-2243
Insulin-like growth factor (IGF)-dependent and -independent antitumor activities of insulin-like growth factor binding protein-3 (IGFBP-3) have been proposed in human non-small cell lung cancer (NSCLC) cells. However, the mechanism underlying regulat
Autor:
J. Jack Lee, Waun Ki Hong, Hye-Young Min, Euni Lee, Ho-Young Lee, Hyo Jong Lee, John Kendal Smith, Diane Liu, Carmen Behrens, Hyun Ji Jang, Ignacio I. Wistuba, Hye Jin Boo, Hye Jeong Yun, Quanri Jin, Hee Seok Kweon
Publikováno v:
Nature Communications
NATURE COMMUNICATIONS(7)
Nature Communications, Vol 7, Iss 1, Pp 1-16 (2016)
NATURE COMMUNICATIONS(7)
Nature Communications, Vol 7, Iss 1, Pp 1-16 (2016)
Nicotinic acetylcholine receptors (nAChRs) binding to the tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) induces Ca2+ signalling, a mechanism that is implicated in various human cancers. In this study, we investigate
Publikováno v:
Cancer Research. 71:S2-7
Background: Trastuzumab is the most successful HER2−directed therapy in patients with early-stage and advanced HER2 positive breast cancer. Although trastuzumab improves survival in the adjuvant setting, 15–20% of the patients develop metastasis.
Publikováno v:
Breast Cancer Research and Treatment. 130:1029-1036
CD44 is an adhesion molecule involved in tumor cell invasion and metastasis. The function of CD44 in breast cancer is not understood completely, or is its role as a predictive or prognostic factor. In this study, we tested for the hypothesis that the
Publikováno v:
Carcinogenesis. 29:1614-1622
The inhibitor of apoptosis protein survivin is selectively expressed in tumor cells. The tobacco component nicotine increases the transcription of the survivin gene in non-small cell lung cancer cells. However, the role of survivin expression induced
Autor:
Jong K. Woo, Seung Hyun Oh, Kyu-Won Kim, Joo-Won Jeong, Hye Jin Kang, Ho-Young Lee, Waun Ki Hong, Quanri Jin
Publikováno v:
International Journal of Cancer. 122:5-14
Hypoxia-inducible factor 1 (HIF-1) plays an essential role in tumor angiogenesis and growth by regulating the transcription of several genes in response to hypoxic stress and changes in growth factors. This study was designed to investigate the effec
Autor:
Chandra Bartholomeusz, Delphine R. Boulbes, Francisco J. Esteva, Quanri Jin, Gaurav B. Chauhan
Publikováno v:
Breast cancer research and treatment. 151(3)
Resistance to HER2-targeted therapies remains a major obstacle in the treatment of HER2-overexpressing breast cancer. CD44, a putative breast cancer stem cell (CSC) marker, is overexpressed in trastuzumab-resistant breast cancer cells. While CSC-rela