Zobrazeno 1 - 10
of 293
pro vyhledávání: '"Quanming, Zou"'
Autor:
Leilei Qin, Ning Hu, Yanhao Zhang, Jianye Yang, Liqun Zhao, Xiaokai Zhang, Yun Yang, Jinyong Zhang, Yinshuang Zou, Keyu Wei, Chen Zhao, Yujian Li, Hao Zeng, Wei Huang, Quanming Zou
Publikováno v:
Journal of Advanced Research, Vol 65, Iss , Pp 239-255 (2024)
Introduction: Treating orthopedic implant-associated infections, especially those caused by Staphylococcus aureus (S. aureus), remains a significant challenge. S. aureus has the ability to invade host cells, enabling it to evade both antibiotics and
Externí odkaz:
https://doaj.org/article/352fc8c80b2b4593881169fe02968693
Autor:
Dongqi Nan, Chenglong Rao, Zhiheng Tang, Wenbo Yang, Pan Wu, Jiangao Chen, Yupei Xia, Jingmin Yan, Wenzheng Liu, Ziyuan Zhang, Zhiqiang Hu, Hai Chen, Yaling Liao, Xuhu Mao, Xiaoyun Liu, Quanming Zou, Qian Li
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Mitophagy is critical for mitochondrial quality control and function to clear damaged mitochondria. Here, we found that Burkholderia pseudomallei maneuvered host mitophagy for its intracellular survival through the type III secretion system
Externí odkaz:
https://doaj.org/article/d0585fa8d04f416e8130477f0b37463e
Autor:
Fumei Luo, Chuanfei Xu, Chengwen Zhang, Aomo Tan, Dongshui Lu, Ping Luo, Ping Cheng, Weijun Zhang, Lijuan Bai, Cuiyun Yu, Si Sun, Hao Zeng, Quanming Zou
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Staphylococcus aureus (S. aureus) possesses numerous virulence factors, with the increasing prevalence of drug-resistant strains heightening the threat posed by this pathogen. Staphylococcal enterotoxin B (SEB), a highly conserved toxin secreted by S
Externí odkaz:
https://doaj.org/article/48f1c258b2854517b3b457ce91b74f24
Autor:
Keran Jia, Yanhao Zhang, Mengyu Jiang, Mengge Cui, Jia Wang, Jiajia Zhang, Hua Wang, Huihai Zhao, Mengyan Li, Quanming Zou, Hao Zeng
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 20, Iss 1 (2024)
Candida albicans Is a leading cause of nosocomial bloodstream infections, particularly in immunocompromised patients. Current therapeutic strategies are insufficient, highlighting the need for effective vaccines. This study aimed to evaluate the effi
Externí odkaz:
https://doaj.org/article/137ff19e11774d048fb72bfb8ec1d592
Autor:
Hongyin Fan, Liqun Zhao, Weiwei Wang, Feng Yu, Haiming Jing, Yun Yang, Xiaoli Zhang, Zhuo Zhao, Qiang Gou, Weijun Zhang, Quanming Zou, Jinyong Zhang, Hao Zeng
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 20, Iss 1 (2024)
Staphylococcal Enterotoxin B (SEB), produced by Staphylococcus aureus (S. aureus), is a powerful superantigen that induces severe immune disruption and toxic shock syndrome (TSS) upon binding to MHC-II and TCR. Despite its significant impact on the p
Externí odkaz:
https://doaj.org/article/0e2b859d386c48189395f41f83e01fba
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 6 (2024)
ABSTRACT Drug efflux systems have recently been recognized as a significant mechanism responsible for multidrug resistance in bacteria. In this study, we described the identification and characterization of a new chromosomally encoded efflux pump (SA
Externí odkaz:
https://doaj.org/article/691921e4879a4572bdbebe5d17c07dd6
Publikováno v:
BMC Microbiology, Vol 24, Iss 1, Pp 1-12 (2024)
Abstract Background The utilization of fructose as a carbon source and energy provider plays a crucial role in bacterial metabolism. Additionally, fructose metabolism directly impacts the pathogenicity and virulence of certain pathogenic microorganis
Externí odkaz:
https://doaj.org/article/bb4fe103ae5b401c99ade437f2cb426a
Autor:
Jingwen Liao, Xiaoli Zhang, Xi Zeng, Zhuo Zhao, Tianjun Sun, Zhenping Xia, Haiming Jing, Yue Yuan, Zhifu Chen, Qiang Gou, Liqun Zhao, Weijun Zhang, Quanming Zou, Jinyong Zhang
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 174, Iss , Pp 116611- (2024)
Background: The emergence of drug-resistant strains of Klebsiella pneumoniae (K. pneumoniae) has become a significant challenge in the field of infectious diseases, posing an urgent need for the development of highly protective vaccines against this
Externí odkaz:
https://doaj.org/article/8256588b09c246b08b0188f069baaea7
Autor:
Yimin Jia, Cun Sun, Ting Chen, Hui Zhu, Tianrui Wang, Yan Ye, Xing Luo, Xiaoqiang Zeng, Yun Yang, Hao Zeng, Quanming Zou, Enqiang Liu, Jieping Li, Hongwu Sun
Publikováno v:
Journal of Nanobiotechnology, Vol 21, Iss 1, Pp 1-17 (2023)
Abstract Acute myeloid leukemia (AML) is an invasive hematopoietic malignancy caused by excessive proliferation of myeloblasts. Classical chemotherapies and cell transplantation therapies have remarkable efficacy in AML treatment; however, 30–40% o
Externí odkaz:
https://doaj.org/article/5344dd2aa046458e9dcaf9bf8ef3a2a1
Autor:
Chunxia Hu, Jinyong Zhang, Ruiqin Cui, Shiyi Liu, Ying Huang, Huan Zeng, Shumin Cheng, Guibao Zhou, Jingli Li, Longqin Sun, Yan Zhao, Xiao Wang, Jianhua Liu, Quanming Zou, Wei Huang
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 169, Iss , Pp 115856- (2023)
Given the important role of polymyxin B (PB) in the treatment of drug-resistant Gram-negative bacterial infections, the emergence of PB resistance poses a serious threat to public health. Adjuvant development is a supplementary strategy that can comp
Externí odkaz:
https://doaj.org/article/9998b69d42ec420f8ff0f737594757c2