Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Quanhai Liu"'
Autor:
Ying Peng, Huanhuan Qi, Qingqing Chang, Yu Zhang, Weiyi Liu, Minyu Liu, Quanhai Liu, Guangji Wang, Jianguo Sun
Publikováno v:
Molecules, Vol 24, Iss 11, p 2082 (2019)
GC20, a novel soluble bis-chelated gold(I)−diphosphine compound, has been reported as a promising anticancer candidate. Assessing the pharmacokinetic properties of GC20 is critical for its medicinal evaluation. First, a sensitive and specific liqui
Externí odkaz:
https://doaj.org/article/8a00698ff1a54f26930a22c0d92f3e41
Autor:
Huang Xiaoling, Tong Wu, Minyu Liu, Yu Pengxia, Yifang Deng, Jintao Zhang, Quanhai Liu, Dong Yuqiong
Publikováno v:
International Immunopharmacology. 66:236-241
Many studies confirmed that the over-activation of RAF-MEK-ERK signaling pathway plays a central role in human cancers. To avoid drug resistance during cancer treatment, many researchers focused on the study of the downstream therapeutic target of RA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9497f9b1aa59015d5714c939cbf69795
https://doi.org/10.1016/j.intimp.2018.11.031
https://doi.org/10.1016/j.intimp.2018.11.031
Publikováno v:
European journal of pharmacology. 826
The aim of this study was to explore the effects of curcumin on renal cell carcinoma（RCC） through regulating autophagy. Cell viabilities were determined by MTT assay in RCC cells after treatment with curcumin at different concentrations for vario
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b14954199852177a3730a12757b3a02a
https://pubmed.ncbi.nlm.nih.gov/29501864
https://pubmed.ncbi.nlm.nih.gov/29501864
Autor:
Quanhai Liu, Huang Xiaoling, Zhen Zhang, Peng-Xia Yu, Minyu Liu, Mei Su, Wang Guoping, Yifang Deng
Publikováno v:
Chinese journal of natural medicines. 16(8)
Farnesoid X receptor (FXR) is a member of the nuclear receptor superfamily of ligand-activated transcription factors. As a metabolic regulator, FXR plays key roles in bile acid and cholesterol metabolism and lipid and glucose homeostasis. Therefore,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04aabd04c769b9781c8a29786bcbeed9
https://pubmed.ncbi.nlm.nih.gov/30197122
https://pubmed.ncbi.nlm.nih.gov/30197122
Autor:
Ming Yin, Haiyan Sun, Yifang Deng, Ying Liu, Yong-Xiang Wang, Minyu Liu, Wei-xia Xiong, Fei Li, Quanhai Liu, Geng-Hui Chen, Lin Xiao, Zhen Zhang, Huang Xiaoling
Publikováno v:
Chinese Journal of Natural Medicines. 12:768-776
Aim JS-38 (mitothiolore), a synthetic version of a metabolite isolated from Xenorhabdus sp., was evaluated for its anti-tumor and white blood cell (WBC) elevating activities. Method These anti-proliferative activities were assessed in vitro using a p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d9840d35600d843b58bf27bf6974b6c
https://doi.org/10.1016/s1875-5364(14)60117-5
https://doi.org/10.1016/s1875-5364(14)60117-5
Autor:
Wei-xia Xiong, Li Cai, Quanhai Liu, Dong Yuqiong, Ying Liu, Minyu Liu, Lin Xiao, Ming Yin, Yu-long Yao
Publikováno v:
Acta Pharmacologica Sinica. 35:1302-1310
To investigate the anticancer effects of S115, a novel heteroaromatic thiosemicarbazone compound in vitro and in vivo.The anti-proliferative action of S115 was analyzed in 12 human and mouse cancer cell lines using MTT assay. Autograft and xenograft
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e90b2ee93a8a991c6c5716fe6927580e
https://doi.org/10.1038/aps.2014.71
https://doi.org/10.1038/aps.2014.71
Publikováno v:
Journal of Chemical Information and Modeling. 52:2730-2740
To discover novel tubulin inhibitors, we performed structure-based virtual screening against the colchicine binding pocket. In combination with a hierarchical docking and scoring procedure, the structural information of an additional subpocket in col
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b02e9c9f06d23bb87fecfe6d63a45e1b
https://doi.org/10.1021/ci300302c
https://doi.org/10.1021/ci300302c
A soluble bis-chelated gold(I) diphosphine compound with strong anticancer activity and low toxicity
Publikováno v:
Journal of medicinal chemistry. 56(4)
Gold-containing compounds have shown anticancer potential, but their clinical applications have been severely limited by poor stability and high toxicity in vivo. Here, we report a novel soluble bis-chelated gold(I)–diphosphine compound (GC20) with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::816ad1b5d6e2a7fb88b6c73671629090
https://pubmed.ncbi.nlm.nih.gov/23362983
https://pubmed.ncbi.nlm.nih.gov/23362983
Publikováno v:
All Days.
Abstract Es3 2+3 reservoir in Gaoshangpu oilfield is a typical field with complex faulted block marginal. In the past ten years, we achieved scale development and gained better economical in Gaoshangpu oilfield by adopting modem reservoir description
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::92ebb2c48670b7a1c0542e110a2abd74
https://doi.org/10.2118/50897-ms
https://doi.org/10.2118/50897-ms
Publikováno v:
Clinical Immunology. 123:S124
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d89d8275f478b102385f3301550b7c1f
https://doi.org/10.1016/j.clim.2007.03.551
https://doi.org/10.1016/j.clim.2007.03.551