Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Quanfeng Zhao"'
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
BackgroundPolatuzumab vedotin, the first FDA-approved antibody-drug conjugate (ADC) targeting CD79b, is utilized in the treatment of previously untreated diffuse large B-cell lymphoma (DLBCL) or high-grade B-cell lymphoma (HGBL), as well as relapsed
Externí odkaz:
https://doaj.org/article/8ee67c8af8764e5fb08c2512c0d2b031
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Externí odkaz:
https://doaj.org/article/eee0b33495424ee0960ea530c0c39940
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Background and purpose: poly-ADP ribose polymerase (PARP) inhibitors show impressive efficacy in a range of tumors. However, concerns about rare and fatal adverse events, including myelodysplastic syndrome (MDS) and acute myelogenous leukemia (AML) h
Externí odkaz:
https://doaj.org/article/d210430aadd74537b292ae915eae8107
Autor:
Xiaoyan Tian, Quanfeng Zhao, Xiaohong Chen, Zhe Peng, Xiaodan Tan, Qin Wang, Lin Chen, Yang Yang
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Background and Objective: COVID-19 has struck our society as a great calamity, and the need for effective anti-viral drugs is more urgent than ever. Papain-like protease (PLpro) of SARS CoV-2 plays important roles in virus maturation, dysregulation o
Externí odkaz:
https://doaj.org/article/41cd732908e542d18b2a30eed6a3f7a1
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2022)
Chemoresistance is a major therapeutic obstacle in the treatment of breast cancer. Therefore, how to overcome chemoresistance is a problem to be solved. Here, a glutathione (GSH)/cathepsin B (CB) dual-controlled nanomedicine formed by cyclic disulfid
Externí odkaz:
https://doaj.org/article/7e9d462c316648ffb14ae939a74a3c56
Autor:
Yang Yang, Qi Chen, Quanfeng Zhao, Ying Luo, Ying Xu, Weimin Du, Hong Wang, Huan Li, Lu Yang, Congli Hu, Jiahua Zhang, Yuke Li, Hui Xia, Zhihao Chen, Jie Ma, Xiaoyan Tian, Junqing Yang
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 13 (2019)
The present study was designed to observe the effect of COX2/PGD2-related autophagy on brain injury in type 2 diabetes rats. The histopathology was detected by haematoxylin–eosin staining. The learning and memory functions were evaluated by Morris
Externí odkaz:
https://doaj.org/article/bfb800f2ff0d4729a7992a0dc747bfe6
Autor:
Chong Li, Songtao Yu, Quanfeng Zhao, Houjie Liang, Zhe Wang, Yuzhu Gong, Jianfang Chen, Jianjun Li, Shuang Wu, Ganfeng Xie
Publikováno v:
Advances in Therapy. 36:1986-1998
To assess the risk factors associated with regorafenib-related adverse events (AEs) in metastatic colorectal cancer (mCRC) and gastrointestinal stromal tumors (GIST). We also evaluated different measures of combatting AEs and their success rate to ai
Autor:
Chong Li, Songtao Yu, Yuzhu Gong, Jianjun Li, Shuang Wu, Ganfeng Xie, Quanfeng Zhao, Houjie Liang, Zhe Wang, Jianfang Chen
Publikováno v:
Journal of Clinical Oncology. 37:e15181-e15181
e15181 Background: Adverse events (AEs) observed in regorafenib treated metastatic colorectal cancer (mCRC) and gastrointestinal stromal tumors (GIST) often require treatment modification. However, due to dearth of literature reporting AE management,