Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Quan-Hai Liu"'
Publikováno v:
Pharmaceutical Fronts, Vol 03, Iss 01, Pp e13-e17 (2021)
As an indispensable part of cancer chemotherapy, platinum drugs still play an important role in cancer treatment. In this study, two platinum(II) complexes with Michael acceptor 3-hydroxyacrylic acid as the leaving group were synthesized from cis-dia
Externí odkaz:
https://doaj.org/article/b270a8ddcabc47ae97eff076dee495ab
Publikováno v:
Molecules, Vol 16, Iss 11, Pp 9368-9385 (2011)
Eighteen novel 3-substituted-indolin-2-ones containing chloropyrroles were synthesized and their biological activities were evaluated. The presence of a chlorine atom on the pyrrole ring was crucial to reduce cardiotoxicity. The presence of a 2-(ethy
Externí odkaz:
https://doaj.org/article/6b309329dbec41528d3ed435cbaa3b87
Publikováno v:
Molecules, Vol 16, Iss 11, Pp 9368-9385 (2011)
Molecules; Volume 16; Issue 11; Pages: 9368-9385
Molecules
Molecules; Volume 16; Issue 11; Pages: 9368-9385
Molecules
Eighteen novel 3-substituted-indolin-2-ones containing chloropyrroles were synthesized and their biological activities were evaluated. The presence of a chlorine atom on the pyrrole ring was crucial to reduce cardiotoxicity. The presence of a 2-(ethy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d5eec3253d9c4953dba4bbf4506de98
http://www.mdpi.com/1420-3049/16/11/9368/
http://www.mdpi.com/1420-3049/16/11/9368/
Publikováno v:
European Journal of Drug Metabolism and Pharmacokinetics. 37:45-56
The metabolism and catabolism of a novel antineoplastic (ID code JS-38),Benzamide, N-[4-(2,4-dimethoxyphenyl)-4,5-dihydro-5-oxo-1,2-dithiolo[4,3-b]pyrrol-6-yl]-3,5-bis (trifluoromethyl)-(9Cl), were investigated in Wistar rats (3 female, 3 male). LC/U
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c83b26080252a33e41e0e7cea1db33d
https://doi.org/10.1007/s13318-011-0055-8
https://doi.org/10.1007/s13318-011-0055-8
Publikováno v:
CNS Neuroscience & Therapeutics. 20:879-881
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3054db37587e3c417a9de3706d0b8062
https://doi.org/10.1111/cns.12310
https://doi.org/10.1111/cns.12310
Publikováno v:
European Journal of Drug Metabolism and Pharmacokinetics. 33:143-148
To evaluate the pre-clinical pharmacokinetics of JS-38(C22H1404N2S2F6, MW: 548), a study was conducted in Wistar rats (3 female, 2 male: 200-250 g about 6 or 7 months). The concentration-time curve of JS-38 in rats demonstrated the pharmacokinetic (P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8b8cfbe29530efcceefe46fe7893cb3
https://doi.org/10.1007/bf03191111
https://doi.org/10.1007/bf03191111
Publikováno v:
Yao xue xue bao = Acta pharmaceutica Sinica. 45(6)
This study is to investigate the effect of ZL-004 on normal mouse and mice with leukopenia induced by chemotherapeutic agents. 5-Fluorouracil were administered intraperitoneally to mice to develop leucopenia, and the mice were treated with ZL-004. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5a32ced45acd6569ee4f2675c76f643f
https://pubmed.ncbi.nlm.nih.gov/20939193
https://pubmed.ncbi.nlm.nih.gov/20939193
Publikováno v:
Molecules; Nov2011, Vol. 16 Issue 11, p9368-9385, 18p, 4 Diagrams, 2 Charts, 1 Graph