Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Quan D, Zhou"'
Autor:
Shan Zhang, Yabo Guo, Gio Fidelito, David R.L. Robinson, Chao Liang, Radiance Lim, Zoë Bichler, Ruiyang Guo, Gaoqi Wu, He Xu, Quan D. Zhou, Brijesh K. Singh, Paul Yen, Dennis Kappei, David A. Stroud, Lena Ho
Publikováno v:
iScience, Vol 26, Iss 9, Pp 107558- (2023)
Summary: LINC00116 encodes a microprotein first identified as Mitoregulin (MTLN), where it was reported to localize to the inner membrane of mitochondria to regulate fatty acid oxidation and oxidative phosphorylation. These initial discoveries were f
Externí odkaz:
https://doaj.org/article/b76d12dc105f40af9b3523b6c63545e2
Autor:
Joseph P. Argus, Moses Q. Wilks, Quan D. Zhou, Wei Yuan Hsieh, Elvira Khialeeva, Xen Ping Hoi, Viet Bui, Shili Xu, Amy K. Yu, Eric S. Wang, Harvey R. Herschman, Kevin J. Williams, Steven J. Bensinger
Publikováno v:
Cell Reports, Vol 25, Iss 10, Pp 2919-2934.e8 (2018)
Summary: It is well understood that fatty acids can be synthesized, imported, and modified to meet requisite demands in cells. However, following the movement of fatty acids through the multiplicity of these metabolic steps has remained difficult. To
Externí odkaz:
https://doaj.org/article/482a607cb48f49f9b41f5484a29a328c
Autor:
Alessandra Ferrari, Quan D. Zhou, Kevin J. Williams, Cuiwen He, An-Chieh Feng, Robert Damoiseaux, Philip O. Scumpia, Autumn G. York, Min Sub Lee, Elizabeth J. Tarling, Allison E. Daly, Viet L. Bui, Steven J. Bensinger, Wei Yuan Hsieh, Eliza B. Kronenberger, Stephen T. Smale, Xun Chi, Jonathan J. Mkrtchyan, Xu Xiao, Peter Tontonoz
Publikováno v:
Nature Immunology. 21:746-755
Plasma membranes of animal cells are enriched for cholesterol. Cholesterol-dependent cytolysins (CDCs) are pore-forming toxins secreted by bacteria that target membrane cholesterol for their effector function. Phagocytes are essential for clearance o
Autor:
Wei Yuan Hsieh, Xen Ping Hoi, Viet L. Bui, Elvira Khialeeva, Xun Chi, Autumn G. York, Young Min Son, Amber Kaplan, Ajit S. Divakaruni, Jie Sun, Richard A. Flavell, Quan D. Zhou, Eliza B. Kronenberger, Stephen T. Smale, Philip O. Scumpia, Kevin J. Williams, Baolong Su, Steven J. Bensinger
Publikováno v:
Cell metabolism, vol 32, iss 1
Cell Metab
Cell Metab
Macrophages reprogram their lipid metabolism in response to activation signals. However, a systems-level understanding of how different pro-inflammatory stimuli reshape the macrophage lipidome is lacking. Here, we use complementary "shotgun" and isot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aec926f48f640925b23bd5002d454a6d
https://escholarship.org/uc/item/0t2554sn
https://escholarship.org/uc/item/0t2554sn
Autor:
Quan D, Zhou, Xun, Chi, Min Sub, Lee, Wei Yuan, Hsieh, Jonathan J, Mkrtchyan, An-Chieh, Feng, Cuiwen, He, Autumn G, York, Viet L, Bui, Eliza B, Kronenberger, Alessandra, Ferrari, Xu, Xiao, Allison E, Daly, Elizabeth J, Tarling, Robert, Damoiseaux, Philip O, Scumpia, Stephen T, Smale, Kevin J, Williams, Peter, Tontonoz, Steven J, Bensinger
Publikováno v:
Nature immunology. 21(7)
Plasma membranes of animal cells are enriched for cholesterol. Cholesterol-dependent cytolysins (CDCs) are pore-forming toxins secreted by bacteria that target membrane cholesterol for their effector function. Phagocytes are essential for clearance o
Autor:
Kevin J. Williams, Eric Wang, Moses Q. Wilks, Quan D. Zhou, Joseph P. Argus, Steven J. Bensinger, Shili Xu, Elvira Khialeeva, Harvey R. Herschman, Amy K. Yu, Viet L. Bui, Wei Yuan Hsieh, Xen Ping Hoi
Publikováno v:
Cell reports, vol 25, iss 10
Cell reports
Cell Reports, Vol 25, Iss 10, Pp 2919-2934.e8 (2018)
Cell reports
Cell Reports, Vol 25, Iss 10, Pp 2919-2934.e8 (2018)
SUMMARY It is well understood that fatty acids can be synthesized, imported, and modified to meet requisite demands in cells. However, following the movement of fatty acids through the multiplicity of these metabolic steps has remained difficult. To
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::144a9f7dcf46e09104974a794bb391b6
https://escholarship.org/uc/item/1nb2x2j7
https://escholarship.org/uc/item/1nb2x2j7
Rapid transcriptional reprogramming of the lipid biosynthesis genes in response to type I interferon
Autor:
Autumn Gabrielle York, Kevin J. Williams, Xin Liu, Joseph P. Argus, Ann-Jay Tong, Quan D. Zhou, Stephen T Smale, Steven Bensinger
Publikováno v:
The Journal of Immunology. 196:202.14-202.14
Cellular lipid requirements are achieved through a combination of biosynthesis and import programs. In previous studies, we found that type I interferon (IFN) signaling shifts the balance of these programs by decreasing synthesis and increasing impor