Zobrazeno 1 - 10
of 1 177
pro vyhledávání: '"Quality by design (QbD)"'
Autor:
Hetvi Triboandas, Mariana Bezerra, Juan Almeida, Matheus de Castro, Bianca Aloise Maneira Corrêa Santos, Walkiria Schlindwein
Publikováno v:
International Journal of Pharmaceutics: X, Vol 8, Iss , Pp 100308- (2024)
This paper presents a comprehensive investigation of the manufacturing of itraconazole (ITZ) amorphous solid dispersions (ASDs) with Kolllidon® VA64 (KVA64) using hot-melt extrusion (HME) and in-line process monitoring, employing a Quality by Design
Externí odkaz:
https://doaj.org/article/8987fd4e4ae440e3a5039380239bb457
Publikováno v:
Journal of Applied Pharmaceutical Research, Vol 12, Iss 2, Pp 57-67 (2024)
Aim: An RP-HPLC method for Vericiguat using the QbD approach was developed and validated by ICH guidelines. Method: The ICH (Q2R1) guidelines have been followed in the development and validation of an RP-HPLC technique by considering several validati
Externí odkaz:
https://doaj.org/article/84182be1b75a441e9759ee98bf14f37a
Autor:
Mustafa M.A. Elsayed, Iman M. Alfagih, Katrina Brockbank, Fawaz Alheibshy, Alhassan H. Aodah, Raisuddin Ali, Khaled Almansour, Ahmed O. Shalash
Publikováno v:
International Journal of Pharmaceutics: X, Vol 7, Iss , Pp 100251- (2024)
The contributions of fine excipient materials to drug dispersibility from carrier-based dry powder inhalation (DPI) formulations are well recognized, although they are not completely understood. To improve the understanding of these contributions, we
Externí odkaz:
https://doaj.org/article/d8ad92ef6a4f4af89ffeb3da1fb442fd
Publikováno v:
Digital Chinese Medicine, Vol 6, Iss 3, Pp 272-284 (2023)
[Abstract]: [Objective]: To explore the application of Quality by Design (QbD) tools in assessing geographical variations of Phyllanthus emblica (P. emblica) from five distinct Indian states. [Methods]: In the current experiment, the Box-Behnken desi
Externí odkaz:
https://doaj.org/article/b2a64de375b544d59c5bbf2c22941206
Publikováno v:
CHIMIA, Vol 78, Iss 3 (2024)
A telescoped, two-step synthesis was investigated by applying Quality by Design principles. A kinetic model consisting of 12 individual reactions was successfully established to describe the synthesis and side reactions. The resulting model predicts
Externí odkaz:
https://doaj.org/article/bc2f52551dd14e20861ac9c410ed0fff
Publikováno v:
Arabian Journal of Chemistry, Vol 17, Iss 3, Pp 105653- (2024)
Background and Objectives: Phycocyanin, a water-soluble blue pigment extracted from cyanobacteria, is used in various industries. Research has explored its health benefits like antioxidants and anti-inflammatory properties. However, challenges remain
Externí odkaz:
https://doaj.org/article/1df2e36fb0ae431b85a7afbc86ba1632
Autor:
Çoban, Özlem a, ⁎, Pınar, Sıla Gülbağ b, Polat, Heybet Kerem a, Gedik, Gülşah c, Karakuyu, Nasıf Fatih d, Pezik, Esra e, Ünal, Sedat f, Mokhtare, Behzad g, Akşit, Aleyna h
Publikováno v:
In Journal of Pharmaceutical Sciences November 2024
Autor:
Julie Horne, Pierre Beckers, Pierre-Yves Sacré, Charlotte De Bleye, Pierre Francotte, Nicolas Thelen, Philippe Hubert, Eric Ziemons, Cédric Hubert
Publikováno v:
Molecules, Vol 29, Iss 14, p 3442 (2024)
A major limitation preventing the use of surface-enhanced Raman scattering (SERS) in routine analyses is the signal variability due to the heterogeneity of metallic nanoparticles used as SERS substrates. This study aimed to robustly optimise a synthe
Externí odkaz:
https://doaj.org/article/20319a04a9a640f689091f41bbb2cf9c
Autor:
Aiswarya Chaudhuri, Dulla Naveen Kumar, Saurabh Kumar Srivastava, Dinesh Kumar, Umesh Kumar Patil, Avanish Singh Parmar, Sanjay Singh, Ashish Kumar Agrawal
Publikováno v:
Pharmaceutics, Vol 16, Iss 7, p 926 (2024)
This study explored the combined administration of docetaxel (DOC) and erlotinib (ERL) using nanostructured lipid carriers (NLCs), with folic acid (FA) conjugation to enhance their synergistic anticancer efficacy against triple-negative breast cancer
Externí odkaz:
https://doaj.org/article/2fa57fbf6b8c4a2191427efa2fa38c4f
Autor:
Amit Gupta, Rashmi Dahima, Sunil K. Panda, Annie Gupta, Gaurav Deep Singh, Tanveer A. Wani, Afzal Hussain, Devashish Rathore
Publikováno v:
Pharmaceutics, Vol 16, Iss 6, p 764 (2024)
Background: Pazopanib hydrochloride (PZB) is a protein kinase inhibitor approved by the United States Food and Drug Administration and European agencies for the treatment of renal cell carcinoma and other renal malignancies. However, it exhibits poor
Externí odkaz:
https://doaj.org/article/32ecd80ac259432caf995a782c04f21d