Zobrazeno 1 - 10
of 9 236
pro vyhledávání: '"Quality by design"'
Autor:
Aliaa Ibnidris, Nektarios Liaskos, Ece Eldem, Angus Gunn, Johannes Streffer, Michael Gold, Mike Rea, Stefan Teipel, Alejandra Gardiol, Marina Boccardi
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-14 (2024)
Abstract Background The Target Product Profile (TPP) is a tool used in industry to guide development strategies by addressing user needs and fostering effective communication among stakeholders. However, they are not frequently used in academic resea
Externí odkaz:
https://doaj.org/article/39784dfc27ff4f1e89abb97c9e5a12aa
Autor:
Christine M. El-Maraghy, Passant M. Medhat, Rania M. Hathout, Miriam F. Ayad, Nermine V. Fares
Publikováno v:
BMC Chemistry, Vol 18, Iss 1, Pp 1-13 (2024)
Abstract A fast eco-friendly colorimetric method was developed for the determination of Tobramycin in drug substance, ophthalmic formulations, and spiked human plasma using silver nanoparticles optical sensor. Even though tobramycin is non-UV–visib
Externí odkaz:
https://doaj.org/article/bc6c2cb5142c49ccbc9e059e134e1857
Publikováno v:
Future Journal of Pharmaceutical Sciences, Vol 10, Iss 1, Pp 1-20 (2024)
Abstract Background The Analytical Quality by Design (AQbD) methodology extends the application of Quality by Design (QbD) principles to the management of the analytical procedure life cycle, encompassing method creation, optimization, validation, an
Externí odkaz:
https://doaj.org/article/d85330907d4a4361a80d0b64846b916a
Autor:
Shadab Anwar Hashmi, Pallavi Alegete
Publikováno v:
BMC Chemistry, Vol 18, Iss 1, Pp 1-19 (2024)
Abstract For the first time a new QbD-assisted green stability indicating ultra-high-performance liquid chromatography (UHPLC) method was developed and validated for quantifying Tolvaptan. The method is simple, quick, cost-effective, and stable, and
Externí odkaz:
https://doaj.org/article/93216584d6e644a99799a29310817f22
Publikováno v:
Journal of Applied Pharmaceutical Research, Vol 12, Iss 2, Pp 57-67 (2024)
Aim: An RP-HPLC method for Vericiguat using the QbD approach was developed and validated by ICH guidelines. Method: The ICH (Q2R1) guidelines have been followed in the development and validation of an RP-HPLC technique by considering several validati
Externí odkaz:
https://doaj.org/article/84182be1b75a441e9759ee98bf14f37a
Publikováno v:
Future Journal of Pharmaceutical Sciences, Vol 10, Iss 1, Pp 1-16 (2024)
Abstract Background Docetaxel (DTX) finds extensive use in treating various cancers, but its limited solubility, side effects, and multi-drug resistance (MDR) hinder its effectiveness. To enhance DTX's properties, the study aimed to formulate DTX-loa
Externí odkaz:
https://doaj.org/article/c36dcbe4489f4d82abaa603920dbe9ad
Autor:
Rayan Y. Mushtaq, Nimbagal Raghavendra Naveen, Krishna Jayanth Rolla, Humood Al Shmrany, Sameer Alshehri, Ahmad Salawi, Mallesh Kurakula, Majed A. Alghamdi, Waleed Y. Rizg, Rana B. Bakhaidar, Walaa A. Abualsunun, Khaled M. Hosny, Abdulmohsin J. Alamoudi
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
IntroductionThe study aimed to systematically enhance the fabrication process of flurbiprofen-loaded bilosomes (FSB) using Quality by Design (QbD) principles and Design of Experiments (DOE). The objective was to develop an optimized formulation with
Externí odkaz:
https://doaj.org/article/84000d3c1f684f31bdbe5508a13b96f7
Publikováno v:
ADMET and DMPK (2024)
Background and purpose: Sorafenib tosylate (SFN), a potent multikinase inhibitor, is used for the treatment of various cancers. However, it shows limited therapeutic applications due to its poor biopharmaceutical properties. The aim of the present in
Externí odkaz:
https://doaj.org/article/36cf157e64134e5b9599e24a1b7566e4
Publikováno v:
Heliyon, Vol 10, Iss 16, Pp e35376- (2024)
In recent years, the field of analytical chemistry has witnessed a notable shift towards the adoption of greener chromatographic methods, aiming to minimize the environmental impact. An effective strategy involves substituting conventional harmful or
Externí odkaz:
https://doaj.org/article/f7351f54579f42c0a243a52739948565