Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Quais N. Hassan"'
Publikováno v:
Frontiers in Neuroscience, Vol 14 (2020)
Environmental enrichment (EE) is an experimental paradigm that is used to explore how a complex, stimulating environment can impact overall health. In laboratory animal experiments, EE housing conditions typically include larger-than-standard cages,
Externí odkaz:
https://doaj.org/article/487320d4653c40e6aab7ee8596c736ab
Autor:
Run Xiao, Anthony G. Mansour, Wei Huang, Quais N. Hassan, Ryan K. Wilkins, Suraj V. Komatineni, Rhiannon Bates, Seemaab Ali, Logan A. Chrislip, Nicholas J. Queen, Shoubao Ma, Jianhua Yu, Matthew R. Lordo, Bethany L. Mundy-Bosse, Michael A. Caligiuri, Lei Cao
Publikováno v:
J Immunol
CD1d, a lipid Ag-presenting molecule for invariant NKT (iNKT) cells, is abundantly expressed on adipocytes and regulates adipose homeostasis through iNKT cells. CD1d gene expression was restored in visceral adipose tissue adipocytes of CD1d knockout
Publikováno v:
Translational cancer research
Social and environmental factors impact cancer and energy balance profoundly. Years ago, our lab established the existence of a novel brain-fat interaction we termed the "hypothalamic-sympathoneural-adipocyte (HSA) axis", through which complex enviro
Autor:
Quais N. Hassan, Jacqueline M. Anderson, Michael A. Caligiuri, Lei Cao, Seemaab Ali, Anthony Mansour, Ryan K. Wilkins, Ripal S. Patel, Nicholas J. Queen, Wei Huang, Xiaokui Mo
Publikováno v:
Aging (Albany NY)
As the elderly population grows, chronic metabolic dysfunction including obesity and diabetes are becoming increasingly common comorbidities. Hypothalamic inflammation through CNS resident microglia serves as a common pathway between developing obesi
Autor:
N. Sebastian, Aleksander Vayntraub, Rohan Deryaniyagala, Janice M. Mehnert, Thomas J. Quinn, Nadine Tayeb, Quais N. Hassan, Bryan S. Squires
Publikováno v:
Cureus
Purpose/objective(s) Merkel cell carcinoma (MCC) is a rare, aggressive cutaneous neoplasm traditionally managed with surgical resection followed by radiotherapy (RT). With the recent approval of checkpoint inhibitors, chemotherapy is less commonly ut
Autor:
Meixiao Long, Quais N. Hassan, Esther Wheeler, Brett Klamer, Kasey Hornbuckle, Youssef Youssef, Robert A. Baiocchi, Amy J. Johnson, Bonnie K. Harrington, Arwa Shana'ah, Lapo Alinari, John C. Byrd, Xiaoli Zhang, Kami J. Maddocks, Lisa L. Smith
Publikováno v:
Leukemia & Lymphoma. 60:2498-2507
Mantle cell lymphoma (MCL) is an aggressive B-cell malignancy for which novel therapeutics with improved efficacy are greatly needed. To provide support for clinical immune checkpoint blockade, we comprehensively evaluated the expression of therapeut
Publikováno v:
Journal of pain and symptom management. 62(3)
It is crucial that physicians understand differing attitudes toward euthanasia and which factors to consider when discussing end-of-life decisions with patients and families from diverse backgrounds.To investigate how attitudes toward euthanasia diff
Publikováno v:
The Journal of clinical investigation. 128(12)
Inhibitors that target specific kinases or oncoproteins have become popular additions to or replacements for cytotoxic chemotherapies to treat many different types of cancer. However, many tumors lack a discernable target kinase and an amplified onco
Autor:
Daniel Canfield, John C. Byrd, Ronni Wasmuth, Casey Cempre, James S. Blachly, Rosa Lapalombella, Shelley Orwick, Lindsey T. Brinton, Katie Williams, Quais N. Hassan, Larry Beaver, Jordan N. Skinner
Publikováno v:
Cancer Research. 79:371-371
Introduction: Mutations in fms-like tyrosine kinase 3 (FLT3) are common genomic abnormalities in adult acute myeloid leukemia (AML). When FLT3 is present as a dominant internal tandem duplication (ITD) AML clone, it is associated with poor treatment