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pro vyhledávání: '"Quadiri Timour"'
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Autor:
Iva Bruhova, Quadiri Timour, Dominique Frassati, Olivier Thériault, Mohamed Chahine, Jean-Martin Beaulieu, Hugo Poulin
Publikováno v:
Molecular Pharmacology. 86:378-389
The voltage-gated Nav1.5 channel is essential for the propagation of action potentials in the heart. Malfunctions of this channel are known to cause hereditary diseases. It is a prime target for class 1 antiarrhythmic drugs and a number of antidepres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53d2cbbbdada6a434a576fd348ba5d8d
https://doi.org/10.1124/mol.114.093104
https://doi.org/10.1124/mol.114.093104
Autor:
Aurore Gouraud, Elodie Sidolle, Michel Ducher, Jacques Caron, Patrice Nony, Sylvain Goutelle, Quadiri Timour
Publikováno v:
Drugs & aging
Drugs & aging, 2014, 31, pp.601-9
Drugs & aging, 2014, 31, pp.601-9
Many elderly patients are routinely exposed to drugs that may prolong the cardiac QT interval and cause Torsades de pointes (TdP). However, predictors of TdP in patients with drug-associated long QT syndrome (LQTS) are not fully understood, especiall
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f9a21f2f91f675f2890f3af6d24a8e8
https://doi.org/10.1007/s40266-014-0188-y
https://doi.org/10.1007/s40266-014-0188-y
Autor:
Quadiri Timour, L. Lerond, Jacques Descotes, Leila Dehina, A. Tabib, V. Blanc-Guillemaud, Ph. Chevalier, N. Dizerens, Fanny Vaillant, Bernard Bui-Xuan, C. Bui-Xuan
Publikováno v:
Naunyn-Schmiedeberg's Archives of Pharmacology. 386:205-215
Myocardial ischemia affects mitochondrial function leading to ionic imbalance and susceptibility to ventricular fibrillation. Trimetazidine (TMZ), a metabolic agent, is clinically used as an anti-anginal therapy. This study was conducted to compare t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::018f048ec69079a73a322aeb014ffac7
https://doi.org/10.1007/s00210-012-0826-z
https://doi.org/10.1007/s00210-012-0826-z
Publikováno v:
Journal of Cardiovascular Pharmacology. 59:523-528
Dronedarone, a recently approved antiarrhythmic drug, has been shown to have fewer side effects than amiodarone, particularly with regard to thyroid and neurologic events. Since the effects of either drug on ventricular defibrillation threshold durin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97195dd16fd4549a5d6f7358b07f3ea7
https://doi.org/10.1097/fjc.0b013e31824d89fe
https://doi.org/10.1097/fjc.0b013e31824d89fe
Autor:
Fanny Vaillant, Zahida Mamou, Bernard Bui-Xuan, Quadiri Timour, Guy Chazot, Leila Dehina, A. Tabib, Muriel Bost, Jacques Descotes, Lamia Hamdan
Publikováno v:
Journal of Trace Elements in Medicine and Biology. 26:170-173
The involvement of psychotropic drugs in sudden deaths has been highlighted. The objective of this work was to establish a link between selenium levels in heart tissue, psychotropic treatment and sudden death. Selenium levels were measured by electro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcffa1cad2321614afaac508d6d89941
https://doi.org/10.1016/j.jtemb.2012.04.025
https://doi.org/10.1016/j.jtemb.2012.04.025
Autor:
Dalila Belhani, Cécile Riera, Bernard Bui-Xuan, Leila Dehina, Philippe Chevalier, Alain Tabib, Quadiri Timour, Alejandro N. Mazzadi, Jacques Descotes, Fanny Vaillant
Publikováno v:
Resuscitation. 82:1092-1099
We showed previously that ivabradine (IVA), a selective inhibitor of the cardiac pacemaker I(f) current, achieved protection against ischaemia-induced ventricular fibrillation (VF) in pigs by increasing the VF threshold (VFT). This was correlated to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6d479aa4ce2ee21d922a60fbeb94556
https://doi.org/10.1016/j.resuscitation.2011.03.032
https://doi.org/10.1016/j.resuscitation.2011.03.032
Autor:
Jacques Descotes, Muriel Bost, Bernard Bui-Xuan, Fanny Vaillant, Waheed Manati, L. Hamdan, Violette Maffre, Quadiri Timour, Dalila Belhani, A. Tabib
Publikováno v:
Human & Experimental Toxicology. 28:461-467
Neuroleptics are a suspected cause of sudden death in psychiatric patients, especially in those with pre-existing cardiac lesions. As these lesions were previously shown to be associated with selenium (Se) deficiency, the aim of the present study was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::871d461b6282962d686a0c06869782aa
https://doi.org/10.1177/0960327109106968
https://doi.org/10.1177/0960327109106968
Autor:
Bernard Bui-Xuan, Fanny Vaillant, L. Fanton, Leila Dehina, Alain Tabib, Jacques Descotes, Daniel Malicier, Ludovic Gomez, Dalila Belhani, Quadiri Timour
Publikováno v:
Experimental and Toxicologic Pathology. 61:317-323
Among 15,000 forensic post-mortem examinations performed on the coroner's order over a 24-year period (January 1981-December 2004) in the area of Lyon, France (population: 2,000,000), 2250 cases of unexpected cardiac sudden death were identified retr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8d0f19abfebe1256e7f3b37c2608539
https://doi.org/10.1016/j.etp.2008.09.007
https://doi.org/10.1016/j.etp.2008.09.007
Autor:
Waheed Manati, Quadiri Timour, Alain Tabib, Jacques Descotes, Fanny Vaillant, Dalila Belhani, L. Fanton, Bernard Bui-Xuan
Publikováno v:
Cardiovascular Toxicology. 9:64-69
Further to our previous observation of post-mortem cardiac lesions after sudden death in several athletes with a history of anabolic steroid abuse, this study was intended to reproduce these lesions in rabbits administered testosterone oenanthate, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::635405e94ea027c4a25ea5a8e3d346dc
https://doi.org/10.1007/s12012-009-9041-7
https://doi.org/10.1007/s12012-009-9041-7