Local emergence in Amazonia of Plasmodium falciparum k13 C580Y mutants associated with in vitro artemisinin resistance

Autor: Luana C Mathieu, Horace Cox, Angela M Early, Sachel Mok, Yassamine Lazrek, Jeanne-Celeste Paquet, Maria-Paz Ade, Naomi W Lucchi, Quacy Grant, Venkatachalam Udhayakumar, Jean SF Alexandre, Magalie Demar, Pascal Ringwald, Daniel E Neafsey, David A Fidock, Lise Musset

Publikováno v: eLife, Vol 9 (2020)

Antimalarial drug resistance has historically arisen through convergent de novo mutations in Plasmodium falciparum parasite populations in Southeast Asia and South America. For the past decade in Southeast Asia, artemisinins, the core component of fi

Externí odkaz: https://doaj.org/article/c827568158c04d0c8f054f163d27f21d

Local emergence in Amazonia of Plasmodium falciparum k13 C580Y mutants associated with in vitro artemisinin resistance

Autor: Venkatachalam Udhayakumar, Sachel Mok, Daniel E. Neafsey, Jeanne-Celeste Paquet, Luana Mathieu, Lise Musset, Magalie Demar, Horace Cox, Maria-Paz Ade, David A. Fidock, Quacy Grant, Angela M. Early, Pascal Ringwald, Yassamine Lazrek, Jean S F Alexandre, Naomi W. Lucchi

Publikováno v: eLife
eLife, 2020, 12, pp.e51015. ⟨10.7554/eLife.51015⟩
eLife, eLife Sciences Publication, 2020, 12, pp.e51015. ⟨10.7554/eLife.51015⟩
eLife, Vol 9 (2020)

International audience; Antimalarial drug resistance has historically arisen through convergent de novo mutations in Plasmodium falciparum parasite populations in Southeast Asia and South America. For the past decade in Southeast Asia, artemisinins,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e6091be7f70e1fbf401299d46864357
https://hal.science/hal-02862736