Zobrazeno 1 - 10
of 95
pro vyhledávání: '"Qizhi Zheng"'
Autor:
Mindy K. Graham, Rulin Wang, Roshan Chikarmane, Bulouere Abel, Ajay Vaghasia, Anuj Gupta, Qizhi Zheng, Jessica Hicks, Polina Sysa-Shah, Xin Pan, Nicole Castagna, Jianyong Liu, Jennifer Meyers, Alyza Skaist, Yan Zhang, Michael Rubenstein, Kornel Schuebel, Brian W. Simons, Charles J. Bieberich, William G. Nelson, Shawn E. Lupold, Theodore L. DeWeese, Angelo M. De Marzo, Srinivasan Yegnasubramanian
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract How prostate cancer cells and their precursors mediate changes in the tumor microenvironment (TME) to drive prostate cancer progression is unclear, in part due to the inability to longitudinally study the disease evolution in human tissues.
Externí odkaz:
https://doaj.org/article/e570ed028e564316b359132fbf5d96e9
Autor:
Karen S. Sfanos, Srinivasan Yegnasubramanian, William G. Nelson, Tamara L. Lotan, Ibrahim Kulac, Jessica L. Hicks, Qizhi Zheng, Charles J. Bieberich, Michael C. Haffner, Angelo M. De Marzo
Publikováno v:
Asian Journal of Urology, Vol 6, Iss 1, Pp 10-25 (2019)
Antibodies are employed ubiquitously in biomedical sciences, including for diagnostics and therapeutics. One of the most important uses is for immunohistochemical (IHC) staining, a process that has been improving and evolving over decades. IHC is use
Externí odkaz:
https://doaj.org/article/f9f935aa6f6f4a879ea3a168a7fbf4b6
Autor:
Igor Vidal, Qizhi Zheng, Jessica L Hicks, Jiayu Chen, Elizabeth A Platz, Bruce J Trock, Ibrahim Kulac, Javier A Baena-Del Valle, Karen S Sfanos, Sarah Ernst, Tracy Jones, Janielle P Maynard, Stephanie A Glavaris, William G Nelson, Srinivasan Yegnasubramanian, Angelo M De Marzo
Publikováno v:
PLoS ONE, Vol 16, Iss 6, p e0241934 (2021)
GSTP1 is a member of the Glutathione-S-transferase (GST) family silenced by CpG island DNA hypermethylation in 90-95% of prostate cancers. However, prostate cancers expressing GSTP1 have not been well characterized. We used immunohistochemistry again
Externí odkaz:
https://doaj.org/article/f8b82cf97d47488885f04952aabfccf4
Autor:
David W. Nauen, Michael C. Haffner, Juyun Kim, Qizhi Zheng, Hao Yin, Angelo M. DeMarzo, Vasiliki Mahairaki, Carlo Colantuoni, J. Geoffrey Pickering, Tory P. Johnson
Publikováno v:
Pathogens, Vol 9, Iss 12, p 1036 (2020)
Nodding syndrome is a pediatric epilepsy disorder associated with Onchocerca volvulus infection, but the mechanism driving this relationship is unclear. One hypothesis proposes that parasite-induced immune responses cross-react with human leiomodin-1
Externí odkaz:
https://doaj.org/article/c0e40889bd52430fa2f88c6044ef54b7
Autor:
Onur Ertunc, Erica Smearman, Qizhi Zheng, Jessica L. Hicks, Jacqueline A. Brosnan-Cashman, Tracy Jones, Carolina Gomes-Alexandre, Levent Trabzonlu, Alan K. Meeker, Angelo M. De Marzo, Christopher M. Heaphy
Telomeres are terminal chromosomal elements that are essential for the maintenance of genomic integrity. The measurement of telomere content provides useful diagnostic and prognostic information, and fluorescent methods have been developed for this p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9ef1a1ba0a18aa40f37adf6313ce02f2
https://doi.org/10.1101/2023.04.04.535575
https://doi.org/10.1101/2023.04.04.535575
Autor:
Karen S. Sfanos, Angelo M. De Marzo, Colm Morrissey, Robert Vessella, Charles G. Drake, Emmanuel S. Antonarakis, Jun Luo, Anne Macgregor-Das, David Esopi, Qizhi Zheng, Shu-Han Yu
Western blot on NCI-H460 cells. Western blot on protein lysates from NCI-H460 cells grown without (1) or with (2) protein transport inhibition with monensin (Golgi-Stop{trade mark, serif}). (3) 300 ng recombinant IL-6, positive control.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5235d5d9675d4634d6d3e9da258e9ef7
https://doi.org/10.1158/2326-6066.22537315
https://doi.org/10.1158/2326-6066.22537315
Autor:
Karen S. Sfanos, Angelo M. De Marzo, Colm Morrissey, Robert Vessella, Charles G. Drake, Emmanuel S. Antonarakis, Jun Luo, Anne Macgregor-Das, David Esopi, Qizhi Zheng, Shu-Han Yu
Supplementary Table S1. Clinical Characteristics of Patient Samples Used in the Study. Supplementary Table S2. Results of Oncomine Database Query for IL-6 Expression. Supplementary Table S3. Assessment of Levels and Distribution of IL-6 mRNA Expressi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5190709ca96f62b160ab45b34250b42
https://doi.org/10.1158/2326-6066.22537309.v1
https://doi.org/10.1158/2326-6066.22537309.v1
Autor:
Angelo M. De Marzo, Marikki Laiho, Ibrahim Kulac, Taija af Hällström, Hester Liu, Alexandra Brodie, Baoyan Bai, Qizhi Zheng, Paul Sirajuddin, Gunes Guner
Supplementary table ("clinicopathological features of cases on the TMAs") and figures (1; "increased 5'ETS/45S CISH signal in cancer glands", 2; "scatterplot showing correlation between 5ʹETS/45S CISH levels by quantitative image analysis and quanti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::937b055a1c3f11f0e584ad248dbd0eda
https://doi.org/10.1158/1541-7786.22511502
https://doi.org/10.1158/1541-7786.22511502
Autor:
Karen S. Sfanos, Angelo M. De Marzo, Colm Morrissey, Robert Vessella, Charles G. Drake, Emmanuel S. Antonarakis, Jun Luo, Anne Macgregor-Das, David Esopi, Qizhi Zheng, Shu-Han Yu
Correlative human studies suggest that the pleiotropic cytokine IL6 contributes to the development and/or progression of prostate cancer. However, the source of IL6 production in the prostate microenvironment in patients has yet to be determined. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4335367d61955ad8777b161294f6dd62
https://doi.org/10.1158/2326-6066.c.6548389.v1
https://doi.org/10.1158/2326-6066.c.6548389.v1
Autor:
Christopher M. Heaphy, Alan K. Meeker, Angelo M. De Marzo, Michael C. Haffner, Michael Considine, Leslie Cope, Qizhi Zheng, Christine Davis, Michael Rubenstein, Lionel Chia, Javier A. Baena Del Valle, Anthony Rizzo, Jacqueline A. Brosnan-Cashman, Joseph Da, Jiyoung Kim, Mindy K. Graham
Table S1. Sequences of oligonucleotides for CRISPR, telomere assays, and RT-qPCR. Table S2. Mean telomere lengths assessed from TRF southern blots of LAPC-4 EV and ATRXKO clones, and CWR22Rv1 EV and ATRXKO clones. Table S3. Microarray results of top
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52650f0d7f552024397c8accb09251af
https://doi.org/10.1158/1541-7786.22512513
https://doi.org/10.1158/1541-7786.22512513