Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Qize Wei"'
Autor:
Qize Wei, Meng Jiao, Xiaoxi Zhu, Nicholas Lombana, Christopher C. Sollecito, Kevin Jimenez-Cowell, Alexander J. Mold, Di Wu
Publikováno v:
Experimental Cell Research. 333:80-92
Pitx2 is a bicoid-related homeobox transcription factor implicated in regulating left-right patterning and organogenesis. However, only a limited number of Pitx2 downstream target genes have been identified and characterized. Here we demonstrate that
Publikováno v:
Molecular biology of the cell. 29(5)
Blebs are involved in various biological processes such as cell migration, cytokinesis, and apoptosis. While the expansion of blebs is largely an intracellular pressure-driven process, the retraction of blebs is believed to be driven by RhoA activati
Publikováno v:
Cell Cycle. 9:4117-4129
The formation of the central spindle (or the spindle midzone) is essential for cytokinesis in animal cells. In this study, we report that coiled-coil domain-containing protein 69 (CCDC69) is implicated in controlling the assembly of central spindles
Publikováno v:
Journal of Biological Chemistry. 285:28643-28650
GIPC1/synectin, a single PDZ domain-containing protein, binds to numerous proteins and is involved in multiple biological processes, including cell migration. We reported previously that MyoGEF, a guanine nucleotide exchange factor, plays a role in r
Publikováno v:
Oncogene. 28:2219-2230
The small guanine triphosphatase (GTPase) proteins RhoA and RhoC are essential for tumor invasion and/or metastasis in breast carcinomas. However, it is poorly understood how RhoA and RhoC are activated in breast cancer cells. Here we describe the ro
Publikováno v:
Molecular Biology of the Cell. 20:1428-1440
Cooperative communications between the central spindle and the contractile ring are critical for the spatial and temporal regulation of cytokinesis. Here we report that MyoGEF, a guanine nucleotide exchange factor that localizes to the central spindl
Autor:
Qize Wei, Jeffrey A. Towbin, Chengyu Liu, Xuefei Ma, Zu-Xi Yu, Kazuyo Takeda, Patricia Zerfas, Michael D. Schneider, Robert S. Adelstein, Aman Singh, Anthony Blount
Publikováno v:
Circulation Research; Vol 105
Circulation Research
Circulation Research
Rationale : Germline ablation of the cytoskeletal protein nonmuscle myosin II (NMII)-B results in embryonic lethality, with defects in both the brain and heart. Tissue-specific ablation of NMII-B by a Cre recombinase strategy should prevent embryonic
Autor:
Qize Wei, Robert S. Adelstein
Publikováno v:
Molecular Biology of the Cell. 13:683-697
We ectopically expressed the transcription factor Pitx2a, one of the Pitx2 isoforms, in HeLa cells by using a tetracycline-inducible expression system and examined whether Pitx2a was capable of modulating Rho GTPase signaling and altering the cell's
Autor:
Takaya Abe, Mary Anne Conti, Mariam C. Recuenco, Tomoko Ohmori, Robert S. Adelstein, Qize Wei, Shunsuke Tanigawa, Sayoko Fujimura, Hiroshi Kiyonari, Atsuhiro Taguchi, Ryuichi Nishinakamura
The kidney develops from reciprocal interactions between the metanephric mesenchyme and ureteric bud. The mesenchyme transforms into epithelia and forms complicated nephron structures, whereas the ureteric bud extends its pre-existing epithelial duct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1468ad724d4d6c37ec259191bb6c7ef
https://europepmc.org/articles/PMC4413762/
https://europepmc.org/articles/PMC4413762/
We previously reported that phosphorylation of myosin II-interacting guanine nucleotide exchange factor (MyoGEF) by polo-like kinase 1 (Plk1) promotes the localization of MyoGEF to the central spindle and increases MyoGEF activity toward RhoA during
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49e634a19ad117a4330e40195659f0b6
https://europepmc.org/articles/PMC3945374/
https://europepmc.org/articles/PMC3945374/