Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Qiyue Luan"'
Publikováno v:
Micromachines, Vol 14, Iss 9, p 1665 (2023)
Microfluidic methods have proven to be effective in separation and isolation of cells for a wide range of biomedical applications. Among these methods, physical trapping is a label-free isolation approach that relies on cell size as the selective phe
Externí odkaz:
https://doaj.org/article/0c647fe001a947ab8bc976d488a54d2f
Publikováno v:
APL Bioengineering, Vol 6, Iss 3, Pp 031501-031501-16 (2022)
Circulating tumor cell (CTC) clusters that are shed from the primary tumor into the bloodstream are associated with a poor prognosis, elevated metastatic potential, higher proliferation rate, and distinct molecular features compared to single CTCs. S
Externí odkaz:
https://doaj.org/article/9c759da844d348d584d569e92a2b58de
Publikováno v:
Micromachines, Vol 14, Iss 4, p 787 (2023)
Single-cell analysis provides a wealth of information regarding the molecular landscape of the tumor cells responding to extracellular stimulations, which has greatly advanced the research in cancer biology. In this work, we adapt such a concept for
Externí odkaz:
https://doaj.org/article/8370bbd32d6d4dd680a8e8ce86d02371
Publikováno v:
APL Bioengineering, Vol 3, Iss 4, Pp 041504-041504-23 (2019)
Massive growth of the microfluidics field has triggered numerous advances in focusing, separating, ordering, concentrating, and mixing of microparticles. Microfluidic systems capable of performing these functions are rapidly finding applications in i
Externí odkaz:
https://doaj.org/article/66c293bcaf974fad93b1f2c1ddfccd2e
Publikováno v:
ELECTROPHORESIS.
Publikováno v:
Lab on a Chip. 22:805-813
Cancer is the leading cause of death globally, with 90% of deaths being caused by cancer metastasis. Circulating tumor cells (CTCs) play an important role in early diagnosis of cancer metastasis and in monitoring of therapeutic response. Therefore, r
Autor:
Qiyue Luan, Jeffrey H. Becker, Celine Macaraniag, Malek G. Massad, Jian Zhou, Takeshi Shimamura, Ian Papautsky
Publikováno v:
Lab Chip
There is a growing interest in developing personalized treatment strategies for each cancer patient, especially those with non-small cell lung carcinoma (NSCLC) which annually accounts for the majority of cancer related deaths in the US. Yet identify
Autor:
Ines Pulido Endrino, Qiyue Luan, Jennifer Graeber, Brianna Borger, Chenghao Ying, Jinhua Li, Zimo Yang, Zhiyong Wang, Yaya Wang, Yuetong Sun, Yan Dai, Ian Papautsky, Thomas L. Prince, Guoqiang Wang, Kevin P. Foley, Weiwen Ying, Takeshi Shimamura
Publikováno v:
Cancer Research. 83:LB231-LB231
KRAS is the most frequently mutated oncogene in cancer and is particularly common in lung, pancreatic and colorectal cancers. While KRAS has been undruggable, covalent KRAS G12C inhibitors, sotorasib and adagrasib, that bind preferentially to GDP-bou
Publikováno v:
Cancer Research. 83:5268-5268
Patient-derived organoids (PDOs) have been widely accepted as ideal 3D tumor models for drug response prediction. However, research involving non-small cell lung cancer (NSCLC) PDOs is hampered by the compromised sample size and the lack of appropria
Publikováno v:
SSRN Electronic Journal.