Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Qiyang Yin"'
Publikováno v:
Journal of Cardiovascular Pharmacology. 74:379-388
Recent reports have established atherosclerosis (AS) as a major factor in the pathogenetic process of cardiovascular diseases such as ischemic stroke and coronary heart disease. Although the possible pathogenesis of AS remains to be elucidated, a lar
Autor:
Yi-ze Li, Weirong Fang, Xiong Zhu, Yuxiang Fei, Yan-ying Qiu, Qiyang Yin, Yunman Li, Bing-wen Liang, Wei-yang Shen, Hongfei Huang
Publikováno v:
Neurochemical Research. 44:1924-1938
Inflammatory reactions and oxidative stress play critical roles in cerebral ischemic injuries. Microglia are activated after ischemic injury. Activated microglia produce neurotoxic proinflammatory factors and reactive oxygen species (ROS), which have
Publikováno v:
Molecular neurobiology. 58(12)
Ischemic stroke is an inflammation-related disease, during which process activation of NLRP3 inflammasome and subsequent pyroptosis play crucial roles. Platelet-activating factor (PAF) is a potent phospholipid regulator of inflammation which exerts i
Publikováno v:
Archives of physiology and biochemistry. 128(6)
Inflammation in the central nervous system (CNS) contributes to disease pathologies by disrupting the integrity of the blood-brain barrier (BBB). Tight junctions (TJ) are a key component of the BBB. Following hypoxic-ischaemic or mechanical injury to
Autor:
Guang-hui Ren, Qiyang Yin, Ye-fang Wang, Jianping Zhu, Bo-wen Wang, Yunman Li, Yuxiang Fei, Bo Zhao, Weirong Fang
Publikováno v:
Bioscience Reports
The present study was designed to investigate the anti-apoptosis effect of Ma xing shi gan decoction (MXD) on PM2.5-induced lung injury via protein kinase B (Akt)/mTOR/p70S6K pathway. A UPLC-MS/MS system was introduced for component analysis of MXD.
Publikováno v:
Brain research bulletin. 164
10-O-(N, N-dimethylaminoethyl) ginkgolide B methanesulfonate (XQ-1H), a novel analog of ginkgolide B, has been preliminarily recognized to show bioactivities against ischemia-induced injury. However, the underlying mechanism still remains to be fully
Autor:
Jianping Zhu, Weirong Fang, Bo-wen Wang, Yunman Li, Bo Zhao, Qiyang Yin, Yuxiang Fei, Ye-fang Wang, Guang-hui Ren
Publikováno v:
Evidence-based Complementary and Alternative Medicine : eCAM
Evidence-Based Complementary and Alternative Medicine, Vol 2020 (2020)
Evidence-Based Complementary and Alternative Medicine, Vol 2020 (2020)
This research was designed to explore the effect of Ma Xing Shi Gan decoction (MXD) in alleviating particulate matter less than 2.5 μm in diameter (PM2.5) induced lung injury from the perspective of epithelial barrier protection and inhibition of ep
Autor:
Yan-ying Qiu, Ye-fang Wang, Bo-wen Wang, Qiyang Yin, Weirong Fang, Yuxiang Fei, Yunman Li, Bo Zhao, Guang-hui Ren
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
Frontiers in Pharmacology
Frontiers in Pharmacology
Ma Xing Shi Gan Decoction (MXD), a classical traditional Chinese medicine prescription, is widely used for the treatment of upper respiratory tract infection. However, the effect of MXD against particulate matters with diameter of less than 2.5 μm (
Autor:
Xiong Zhu, Bing-wen Liang, Qiyang Yin, Wei-yang Shen, Yunman Li, Bo Zhao, Jianping Zhu, Yuxiang Fei
Publikováno v:
Life Sciences. 260:118221
JLX001, a new dihydrochloride of Cyclovirobuxine D (CVB-D), has bioactivities against ischemia injury. The blood-brain barrier (BBB) disruption is involved in the pathogeneses of ischemic stroke. This study was designed to explore the effect and pote
Autor:
Jianping Zhu, Bo Zhao, Wei-yang Shen, Yuman Li, Qiyang Yin, Xiong Zhu, Bing-wen Liang, Yuxiang Fei
Publikováno v:
Life Sciences. 257:118083
Aims To investigate the preclinical pharmacodynamics and mechanism of JLX001 against myocardial ischemia reperfusion (MI/R) for clinical application. Materials and methods In vivo, SD rats were given intragastric administration for 5 days, and the MI