Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Qiwang Xiang"'
Autor:
Ran-Der Hwang, YuNing Lu, Qing Tang, Goran Periz, Giho Park, Xiangning Li, Qiwang Xiang, Yang Liu, Tao Zhang, Jiou Wang
Publikováno v:
eLife, Vol 12 (2024)
Proteotoxic stress impairs cellular homeostasis and underlies the pathogenesis of many neurodegenerative diseases, including amyotrophic lateral sclerosis (ALS). The proteasomal and autophagic degradation of proteins are two major pathways for protei
Externí odkaz:
https://doaj.org/article/66d2bdce60404733afc2652e8b8c8360
Publikováno v:
PLoS Pathogens, Vol 19, Iss 11, p e1011806 (2023)
Human herpesvirus 8 (HHV-8) encodes four viral interferon regulatory factors (vIRFs) that target cellular IRFs and/or other innate-immune and stress signaling regulators and suppress the cellular response to viral infection and replication. For vIRF-
Externí odkaz:
https://doaj.org/article/6bc7a849263843dc96979c4eb790cf16
Publikováno v:
PLoS Pathogens, Vol 18, Iss 7, p e1010676 (2022)
Human herpesvirus 8 (HHV-8), also known as Kaposi's sarcoma (KS)-associated herpesvirus, is involved etiologically in AIDS-associated KS, primary effusion lymphoma (PEL), and multicentric Castleman's disease, in which both viral latent and lytic func
Externí odkaz:
https://doaj.org/article/79a5ee72fb91437194eb37d67139e521
Publikováno v:
J Virol
Human herpesvirus 8 (HHV-8) viral interleukin-6 (vIL-6) is a cytokine that is poorly secreted and localized largely to the endoplasmic reticulum (ER). It has been implicated, along with other HHV-8 proinflammatory and/or angiogenic viral proteins, in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76bbf6ea3c12c0b63e74f9fe2ae62568
https://europepmc.org/articles/PMC7495386/
https://europepmc.org/articles/PMC7495386/
Publikováno v:
Journal of Virology
Human herpesvirus 8-encoded IRF homologues were the first to be identified in a virus. Through inhibitory interactions with cellular IRFs and other mediators of antiviral signaling, the vIRFs are believed to be essential for productive replication an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43acb0f5604d1a3943a12275de438a59
https://doi.org/10.1128/jvi.01553-19
https://doi.org/10.1128/jvi.01553-19
Human herpesvirus 8 (HHV-8) viral interleukin-6 (vIL-6) localizes largely to the endoplasmic reticulum (ER) and here associates functionally with both the gp130 signal transducer and the novel ER membrane protein vitamin K epoxide reductase complex s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8227348899101847f2ddcdfe2be7ad92
https://europepmc.org/articles/PMC6384062/
https://europepmc.org/articles/PMC6384062/
Autor:
Szu Chieh Mei, Daming Chen, Hyunwoo Ju, John Nicholas, Young Bong Choi, Qian Li, Qiwang Xiang
Human herpesvirus 8 (HHV-8) encodes four viral interferon regulatory factors (vIRF-1 to -4) that likely function to suppress innate immune and cellular stress responses through inhibitory interactions with various cellular proteins involved in these
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11cde64936a3d7689f877fb79fa8af1d
https://europepmc.org/articles/PMC5972880/
https://europepmc.org/articles/PMC5972880/
Publikováno v:
Journal of virology. 91(22)
Viral interleukin-6 (vIL-6) encoded by human herpesvirus 8 (HHV-8) is believed to contribute via mitogenic, survival, and angiogenic activities to HHV-8-associated Kaposi's sarcoma, primary effusion lymphoma (PEL), and multicentric Castleman's diseas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::344b0357bc5d380f30729a06cf4d41dc
https://pubmed.ncbi.nlm.nih.gov/28878084
https://pubmed.ncbi.nlm.nih.gov/28878084
Publikováno v:
Journal of Virology. 1/15/2020, Vol. 94 Issue 2, p1-24. 24p.
Autor:
Qiwang Xiang1, Hyunwoo Ju1, Qian Li1, Szu-Chieh Mei1, Daming Chen1, Young Bong Choi1, Nicholas, John1 nichojo@jhmi.edu
Publikováno v:
Journal of Virology. Apr2018, Vol. 92 Issue 7, p1-20. 20p.