Zobrazeno 1 - 10
of 72
pro vyhledávání: '"Qiuyuan Wen"'
Autor:
Ying Zhou, Yaoxiang Tang, Jiadi Luo, Yang Yang, Hongjing Zang, Jian Ma, Songqing Fan, Qiuyuan Wen
Publikováno v:
BMC Oral Health, Vol 23, Iss 1, Pp 1-10 (2023)
Abstract Background HSP60 is a heat shock proteins (HSPs) family member and help mitochondrial protein to fold correctly. Survivin is one of the inhibitors of apoptosis protein family member, which plays a significant part in cancer progression. They
Externí odkaz:
https://doaj.org/article/395877911e3e4d8892ab87f929ab5153
Publikováno v:
Cell & Bioscience, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract Lung cancer is a complex and heterogeneous disease characterized by abnormal growth and proliferation of lung cells. It is the leading cause of cancer-related deaths worldwide, accounting for approximately 18% of all cancer deaths. In recent
Externí odkaz:
https://doaj.org/article/cea90938cc144d0b830b6baa1da69734
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 42, Iss 1, Pp 1-14 (2023)
Abstract AXL is a member of the TAM (TYRO3, AXL, and MERTK) receptor tyrosine kinases family (RTKs), and its abnormal expression has been linked to clinicopathological features and poor prognosis of cancer patients. There is mounting evidence support
Externí odkaz:
https://doaj.org/article/1678b36d8df44b07a566e94c1aac4500
Autor:
Yue Ning, Yang Yang, Hongmei Zheng, Yuting Zhan, Hongjing Zang, Qiuyuan Wen, Jinwu Peng, Songqing Fan
Publikováno v:
Cancer Medicine, Vol 12, Iss 2, Pp 1616-1629 (2023)
Abstract FAT4 is an extremely large atypical cadherin with crucial roles in the control of planar cell polarity (PCP) and regulation of the Hippo signaling pathway. Our study aims to clarify the FAT4 expression patterns, as well as the significance o
Externí odkaz:
https://doaj.org/article/efe02d339fb24665b468316c61f43d6e
Autor:
Yaoxiang Tang, Jiadi Luo, Ying Zhou, Hongjing Zang, Yang Yang, Sile Liu, Hongmei Zheng, Jian Ma, Songqing Fan, Qiuyuan Wen
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-11 (2022)
Abstract Background Ribosomal protein S6 (S6), a downstream effect media of the AKT/mTOR pathway, not only is a part of 40S small subunit of eukaryotic ribosome, but also involves in protein synthesis and cell proliferation during cancer development.
Externí odkaz:
https://doaj.org/article/3255522741b9492c822e0d08b5d1a650
Autor:
Jie Liu, Wei Huang, Caiping Ren, Qiuyuan Wen, Weidong Liu, Xuyu Yang, Lei Wang, Bin Zhu, Liang Zeng, Xiangling Feng, Chang Zhang, Huan Chen, Wei Jia, Lihua Zhang, Xiaomeng Xia, Yuxiang Chen
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-2 (2023)
Externí odkaz:
https://doaj.org/article/c1887c9d958d444c8eb7aedadcc41388
Autor:
Sile Liu, Weiyuan Wang, Yue Ning, Hongmei Zheng, Yuting Zhan, Haihua Wang, Yang Yang, Jiadi Luo, Qiuyuan Wen, Hongjing Zang, Jinwu Peng, Jian Ma, Songqing Fan
Publikováno v:
Cell Death and Disease, Vol 13, Iss 2, Pp 1-14 (2022)
Abstract Everolimus is a kind of mammalian target of rapamycin (mTOR) inhibitors. Activated mitogen-activated protein kinase interacting kinases/eukaryotic translation initiation factor 4E (MNK/eIF4E) axis plays a crucial role in resistance to Everol
Externí odkaz:
https://doaj.org/article/783921d489244b8c9f811b22f6a00938
Publikováno v:
Thoracic Cancer, Vol 11, Iss 9, Pp 2704-2708 (2020)
Abstract The role of the epidermal growth factor receptor (EGFR) mutation status testing in lung squamous cell carcinoma (SqCC) remains controversial. Evidence of the effectiveness of osimertinib in SqCC with EGFR T790M mutation is limited. Here, we
Externí odkaz:
https://doaj.org/article/318bac3417ca4ebf952573c357130100
Autor:
Yue Ning, Hongmei Zheng, Yuting Zhan, Sile Liu, Yang yang, Hongjing Zang, Jiadi Luo, Qiuyuan Wen, Songqing Fan
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 39, Iss 1, Pp 1-10 (2020)
Abstract Aberrant expression of mucin proteins has played a complex and essential role in cancer development and metastasis. Members of the mucin family have been intimately implicated in lung cancer progression, metastasis, survival and chemo-resist
Externí odkaz:
https://doaj.org/article/a4216330775546d08d28dee4044a4585
Autor:
Yaoxiang Tang, Jiadi Luo, Yang Yang, Sile Liu, Hongmei Zheng, Yuting Zhan, Songqing Fan, Qiuyuan Wen
Publikováno v:
PLoS ONE, Vol 17, Iss 6, p e0265465 (2022)
Eukaryotic initiation factor 4E (eIF4E) and its phosphorylated form (p-eIF4E) play a crucial role in the protein synthesis, both are under regulation of eIF4E-binding protein 1 (4EBP1) and mitogen-activated protein kinase (MAPK)-interacting kinases (
Externí odkaz:
https://doaj.org/article/09e904702e8341358a8498b0b5708363