Zobrazeno 1 - 10
of 124
pro vyhledávání: '"Qiuying Sha"'
Autor:
Anjum Shaik, Kristoffer Larsen, Nancy E. Lane, Chen Zhao, Kuan-Jui Su, Joyce H. Keyak, Qing Tian, Qiuying Sha, Hui Shen, Hong-Wen Deng, Weihua Zhou
Publikováno v:
Bone Reports, Vol 22, Iss , Pp 101805- (2024)
Hip fractures present a significant healthcare challenge, especially within aging populations, where they are often caused by falls. These fractures lead to substantial morbidity and mortality, emphasizing the need for timely surgical intervention. D
Externí odkaz:
https://doaj.org/article/72ff07d14f2343cf963820df19849a0d
Publikováno v:
Frontiers in Genetics, Vol 15 (2024)
Genome-wide association studies (GWAS) have emerged as popular tools for identifying genetic variants that are associated with complex diseases. Standard analysis of a GWAS involves assessing the association between each variant and a disease. Howeve
Externí odkaz:
https://doaj.org/article/ea09467ed4974edc98d2635148a06cc0
Publikováno v:
PLoS Genetics, Vol 20, Iss 5, p e1011245 (2024)
Joint analysis of multiple correlated phenotypes for genome-wide association studies (GWAS) can identify and interpret pleiotropic loci which are essential to understand pleiotropy in diseases and complex traits. Meanwhile, constructing a network bas
Externí odkaz:
https://doaj.org/article/024866a8bb0a4641bde77e182830082b
Autor:
Chen Zhao, Joyce H. Keyak, Xuewei Cao, Qiuying Sha, Li Wu, Zhe Luo, Lan-Juan Zhao, Qing Tian, Michael Serou, Chuan Qiu, Kuan-Jui Su, Hui Shen, Hong-Wen Deng, Weihua Zhou
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
BackgroundHip fracture occurs when an applied force exceeds the force that the proximal femur can support (the fracture load or “strength”) and can have devastating consequences with poor functional outcomes. Proximal femoral strengths for specif
Externí odkaz:
https://doaj.org/article/41f27814caf746efa6a4af37bfe51164
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract There is strong evidence showing that joint analysis of multiple phenotypes in genome-wide association studies (GWAS) can increase statistical power when detecting the association between genetic variants and human complex diseases. We previ
Externí odkaz:
https://doaj.org/article/788b4276ea1546ea90afe0554debaab2
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract Although genome-wide association studies (GWAS) have been successfully applied to a variety of complex diseases and identified many genetic variants underlying complex diseases via single marker tests, there is still a considerable heritabil
Externí odkaz:
https://doaj.org/article/2d333728491544e0bb311965dd8eb352
Autor:
Nongthombam Boby, Xuewei Cao, Kelsey Williams, Shiva Kumar Goud Gadila, Monica N. Shroyer, Peter J. Didier, Sudesh K. Srivastav, Arpita Das, Kate Baker, Qiuying Sha, Bapi Pahar
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Angiotensin converting enzyme-2 (ACE2) and associated proteins play a pivotal role in various physiological and pathological events, such as immune activation, inflammation, gut barrier maintenance, intestinal stem cell proliferation, and apoptosis.
Externí odkaz:
https://doaj.org/article/c46204a529e04467be250943fd6fb087
Publikováno v:
PLoS ONE, Vol 17, Iss 11, p e0276646 (2022)
The emergence of genetic data coupled to longitudinal electronic medical records (EMRs) offers the possibility of phenome-wide association studies (PheWAS). In PheWAS, the whole phenome can be divided into numerous phenotypic categories according to
Externí odkaz:
https://doaj.org/article/609c277edf4241218950b8f546d6301b
Publikováno v:
PLoS ONE, Vol 17, Iss 4, p e0260911 (2022)
There has been an increasing interest in joint analysis of multiple phenotypes in genome-wide association studies (GWAS) because jointly analyzing multiple phenotypes may increase statistical power to detect genetic variants associated with complex d
Externí odkaz:
https://doaj.org/article/562b0ce5951545dcb8f5ef16c0d71e58
Autor:
Nongthombam Boby, Xuewei Cao, Alyssa Ransom, Barcley T. Pace, Christopher Mabee, Monica N. Shroyer, Arpita Das, Peter J. Didier, Sudesh K. Srivastav, Edith Porter, Qiuying Sha, Bapi Pahar
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Epithelial cell injury and impaired epithelial regeneration are considered key features in HIV pathogenesis and contribute to HIV-induced generalized immune activation. Understanding the molecular mechanisms underlying the disrupted epithelial regene
Externí odkaz:
https://doaj.org/article/b5121de0ff944f71a8645d3377203f3d