Zobrazeno 1 - 10
of 73
pro vyhledávání: '"Qiuyi, Chi"'
Autor:
Kieop Park, Ranjay Jayadev, Sara G Payne, Isabel W Kenny-Ganzert, Qiuyi Chi, Daniel S Costa, William Ramos-Lewis, Siddharthan B Thendral, David R Sherwood
Publikováno v:
eLife, Vol 12 (2023)
Separate tissues connect through adjoining basement membranes to carry out molecular barrier, exchange, and organ support functions. Cell adhesion at these connections must be robust and balanced to withstand independent tissue movement. Yet, how cel
Externí odkaz:
https://doaj.org/article/5e5db74a213b4415b17418b13699a45d
Autor:
Hitoshi Kida, Yosuke Fukutani, Joel D. Mainland, Claire A. de March, Aashutosh Vihani, Yun Rose Li, Qiuyi Chi, Akemi Toyama, Linda Liu, Masaharu Kameda, Masafumi Yohda, Hiroaki Matsunami
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
Biomimetic “noses” have been proposed to replace trained animals for chemical detection. Here the authors select 31 mouse olfactory receptors (ORs), based on a large cell-based screen of >800 ORs against seven chemicals, to build an OR-based sens
Externí odkaz:
https://doaj.org/article/4bb70edca5cc4c01907d20a917e26727
Autor:
Daniel S. Costa, Isabel W. Kenny-Ganzert, Qiuyi Chi, Kieop Park, Laura C. Kelley, Aastha Garde, David Q. Matus, Junhyun Park, Shaul Yogev, Bob Goldstein, Theresa V. Gibney, Ariel M. Pani, David R. Sherwood
Publikováno v:
Development. 150
Cell invasion through basement membrane (BM) barriers is important in development, immune function and cancer progression. As invasion through BM is often stochastic, capturing gene expression profiles of actively invading cells in vivo remains elusi
Autor:
Daniel S. Costa, Isabel W. Kenny-Ganzert, Qiuyi Chi, Kieop Park, Laura C. Kelley, Aastha Garde, David Q. Matus, Junhyun Park, Shaul Yogev, Bob Goldstein, Theresa V. Gibney, Ariel M. Pani, David R. Sherwood
Cell invasion through basement membrane (BM) barriers is important in development, immune function, and cancer progression. As invasion through BM is often stochastic, capturing gene expression profiles of cells actively transmigrating BMin vivoremai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6a2340ea4b25cfbf19f0c6a437dc750b
https://doi.org/10.1101/2022.12.28.522136
https://doi.org/10.1101/2022.12.28.522136
Autor:
Claire A. Gianakas, Daniel P. Keeley, William Ramos-Lewis, Kieop Park, Ranjay Jayadev, Isabel W. Kenny, Qiuyi Chi, David R. Sherwood
Publikováno v:
Journal of Cell Biology. 222
Basement membrane (BM) matrices surround and separate most tissues. However, through poorly understood mechanisms, BMs of adjacent tissue can also stably link to support organ structure and function. Using endogenous knock-in fluorescent proteins, co
Autor:
Costa, Daniel S., Kenny-Ganzert, Isabel W., Qiuyi Chi, Kieop Park, Kelley, Laura C., Garde, Aastha, Matus, David Q., Junhyun Park, Yogev, Shaul, Goldstein, Bob, Gibney, Theresa V., Pani, Ariel M., Sherwood, David R.
Publikováno v:
Development (09501991); May2023, Vol. 150 Issue 9, p1-18, 18p
Autor:
Ranjay, Jayadev, Mychel R P T, Morais, Jamie M, Ellingford, Sandhya, Srinivasan, Richard W, Naylor, Craig, Lawless, Anna S, Li, Jack F, Ingham, Eric, Hastie, Qiuyi, Chi, Maryline, Fresquet, Nikki-Maria, Koudis, Huw B, Thomas, Raymond T, O'Keefe, Emily, Williams, Antony, Adamson, Helen M, Stuart, Siddharth, Banka, Damian, Smedley, David R, Sherwood, Rachel, Lennon
Publikováno v:
Genomics England Research Consortium 2022, ' A basement membrane discovery pipeline uncovers network complexity, new regulators, and human disease associations ', Science Advances, vol. 8, no. 20, eabn2265 . https://doi.org/10.1126/sciadv.abn2265
Basement membranes (BMs) are ubiquitous extracellular matrices whose composition remains elusive, limiting our understanding of BM regulation and function. By developing a bioinformatic and in vivo discovery pipeline, we define a network of 222 human
Autor:
Shelly TH McClatchey, Zheng Wang, Lara M Linden, Eric L Hastie, Lin Wang, Wanqing Shen, Alan Chen, Qiuyi Chi, David R Sherwood
Publikováno v:
eLife, Vol 5 (2016)
Epithelial cells and their underlying basement membranes (BMs) slide along each other to renew epithelia, shape organs, and enlarge BM openings. How BM sliding is controlled, however, is poorly understood. Using genetic and live cell imaging approach
Externí odkaz:
https://doaj.org/article/d44a600026ea4b88b0b999bdeeb58cfa
SPARC Promotes Cell Invasion In Vivo by Decreasing Type IV Collagen Levels in the Basement Membrane.
Autor:
Meghan A Morrissey, Ranjay Jayadev, Ginger R Miley, Catherine A Blebea, Qiuyi Chi, Shinji Ihara, David R Sherwood
Publikováno v:
PLoS Genetics, Vol 12, Iss 2, p e1005905 (2016)
Overexpression of SPARC, a collagen-binding glycoprotein, is strongly associated with tumor invasion through extracellular matrix in many aggressive cancers. SPARC regulates numerous cellular processes including integrin-mediated cell adhesion, cell
Externí odkaz:
https://doaj.org/article/acc6c9883f994a33b3a930937db516a6
Autor:
Lauren L Lohmer, Matthew R Clay, Kaleb M Naegeli, Qiuyi Chi, Joshua W Ziel, Elliott J Hagedorn, Jieun E Park, Ranjay Jayadev, David R Sherwood
Publikováno v:
PLoS Genetics, Vol 12, Iss 1, p e1005786 (2016)
Invadopodia are specialized membrane protrusions composed of F-actin, actin regulators, signaling proteins, and a dynamically trafficked invadopodial membrane that drive cell invasion through basement membrane (BM) barriers in development and cancer.
Externí odkaz:
https://doaj.org/article/f44cb6e4aa5b4ce4bcd0920fecf8f975