Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Qiushi Gao"'
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 131, Iss , Pp 110733- (2020)
General anaesthesia may impose significant neurocognitive risks on the developing brain. As brain injury in preterm neonates has a particular predilection for cerebral white matter, we aimed to evaluate the effects of sevoflurane on oligodendrocyte m
Externí odkaz:
https://doaj.org/article/ae768d64883d4369a745f69db7b6b68b
Publikováno v:
Materials, Vol 11, Iss 1, p 44 (2017)
The CrS/NbC Co-based self-lubricating composite coatings were successfully fabricated on Cr12MoV steel surface by laser clad Stellite 6, WS2, and NbC mixed powders. The phase composition, microstructure, and tribological properties of the coatings wa
Externí odkaz:
https://doaj.org/article/107206c19b0f40c78e3cc2e3c1ee4494
Publikováno v:
CNS neurosciencetherapeutics. 28(12)
Hypoxic-ischemic brain injury (HIBI) often results in cognitive impairments. Herein, we investigated the roles of ferroptosis in HIBI and the underlying signaling pathways.Ferrostatin-1 (Fer-1) or resveratrol (Res) treatments were administered intrac
Publikováno v:
Journal of Clinical Anesthesia. 86:111075
Publikováno v:
Cellular and Molecular Neurobiology. 42:1777-1786
With the increase in fetal surgeries, the effect of maternal anesthesia on progeny has attracted much attention. Our previous studies have demonstrated that 3.5% sevoflurane maternal exposure resulted in over-activated autophagy and cognitive impairm
Publikováno v:
Cellular and Molecular Neurobiology. 41:1801-1816
Microglia/macrophages have been identified to be highly polarized after ischemia. Interestingly, the polarization of these microglia/macrophages varies immensely under differing disease conditions. Post-conditioning using sevoflurane, a volatile anes
Publikováno v:
Drug Design, Development and Therapy. 13:4439-4449
Background Dexmedetomidine (Dex) is a highly selective α2-adrenoceptor agonist used as an off-label medication for pediatric sedation and analgesia. Recently, Dex was reported to exhibit neuroprotective efficacy in several brain injury models. Here
Autor:
Jiayuan Niu, Xingyue Li, Hang Xue, Qiushi Gao, Shuo Wang, Ziyi Wu, Yahan Zhang, Ping Zhao, Ying Xu
Publikováno v:
Drug Design, Development and Therapy. 13:1691-1706
Background: When neonatal rats suffer hypoxic-ischemic brain injury (HIBI), autophagy is over-activated in the hippocampus, and inhibition of autophagy provides neuroprotection. The aim of this study was to investigate the possible roles of autophagy
Publikováno v:
Optics & Laser Technology. 113:182-191
TiN reinforced Ni matrix composite coating with in-situ synthesized TiS lubricant phase were fabricated on Ti-6Al-4V alloy by laser cladding with NiCrBSi, TiN and WS2 powder mixtures. The phase compositions, microstructure, microhardness and tribolog
Publikováno v:
Life sciences. 270
Background Hypoxic-ischemic brain injury (HIBI) is a major cause of mortality in neonates and can cause long-term neurological sequelae. Excessive autophagy caused by HI may cause neuronal death. Dexmedetomidine was reported neuroprotective against H