Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Qiusheng Tong"'
Autor:
Eunan Hendron, Qiusheng Tong, James D. Stockand, Elena Mironova, Nina Boiko, Volodymyr Kucher, Alexey V. Karpushev, Oleh Pochynyuk, Alexander Staruschenko
Publikováno v:
Journal of Biological Chemistry. 284:25512-25521
Tryptophan residues critical to function are frequently located at the lipid-water interface of transmembrane domains. All members of the epithelial Na+ channel (ENaC)/Degenerin (Deg) channel superfamily contain an absolutely conserved Trp at the bas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e522cc3615a3e4c67e5b276c9007ef57
https://doi.org/10.1074/jbc.m109.015917
https://doi.org/10.1074/jbc.m109.015917
Publikováno v:
The Journal of Physiology. 580:365-372
Several distinct types of ion channels bind and directly respond to phosphatidylinositides, including phosphatidylinositol (3,4,5)-trisphosphate (PI(3,4,5)P3) and phosphatidylinositol (4,5)-bisphosphate (PI(4,5)P2). This regulation is physiologically
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b643962eb78a63338db32bd5dc9f8049
https://doi.org/10.1113/jphysiol.2006.127449
https://doi.org/10.1113/jphysiol.2006.127449
Publikováno v:
Journal of Biological Chemistry. 280:37565-37571
Membrane phospholipids, such as phosphatidylinositol 3,4,5-trisphosphate (PI(3,4,5)P(3)), are signaling molecules that can directly modulate the activity of ion channels, including the epithelial Na(+) channel (ENaC). Whereas PI(3,4,5)P(3) directly a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0915a0f33d2107dfb4e81382b0c9b648
https://doi.org/10.1074/jbc.m509071200
https://doi.org/10.1074/jbc.m509071200
Autor:
Rebecca P. Hughey, Qiusheng Tong, Thomas R. Kleyman, Marcelo D. Carattino, Carol L. Kinlough, James B. Bruns, Keri L. Harkleroad, James D. Stockand, John P. Johnson
Publikováno v:
Journal of Biological Chemistry. 279:18111-18114
Epithelial Na(+) channels (ENaCs) are activated by extracellular trypsin or by co-expression with channel-activating proteases, although there is no direct evidence that these proteases activate ENaC by cleaving the channel. We previously demonstrate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f84b306b1fd759d19a7aa17c9bf0bf0c
https://doi.org/10.1074/jbc.c400080200
https://doi.org/10.1074/jbc.c400080200
Publikováno v:
American Journal of Physiology-Cell Physiology. 278:C661-C666
The sarcolemmal Na/Ca exchanger undergoes an inactivation process in which exchange activity decays over several seconds following activation by the application of Na to the intracellular surface of the protein. Inactivation is eliminated by an incre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3efe3163ea63c16cd62bd8e5586cfd5
https://doi.org/10.1152/ajpcell.2000.278.4.c661
https://doi.org/10.1152/ajpcell.2000.278.4.c661
Autor:
Jorge Medina, Alexander Staruschenko, Alain Vandewalle, Vladislav Bugaj, Oleh Pochynyuk, James D. Stockand, Qiusheng Tong
Publikováno v:
The Journal of General Physiology
Phosphatidylinositol 4,5-bisphosphate (PI(4,5)P(2)) and phosphatidylinositol 3,4,5-trisphosphate (PI(3,4,5)P(3)) are physiologically important second messengers. These molecules bind effector proteins to modulate activity. Several types of ion channe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7df9cba1a5bb5b6b08521277a2b8d1de
https://pubmed.ncbi.nlm.nih.gov/17893193
https://pubmed.ncbi.nlm.nih.gov/17893193
Autor:
James D. Stockand, Qiusheng Tong
Publikováno v:
The FASEB Journal. 21
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3e03509e0b23c13444185e3d0b3b69eb
https://doi.org/10.1096/fasebj.21.5.a545
https://doi.org/10.1096/fasebj.21.5.a545
Autor:
Alexander, Staruschenko, Rachell E, Booth, Oleh, Pochynyuk, James D, Stockand, Qiusheng, Tong
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 337
Probing ion channel structure-function and regulation in native tissue can, in some instances, be experimentally challenging or impractical. To facilitate discovery and increase experimental flexibility, our laboratory routinely reconstitutes recombi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6be908b65ccd34e5a3f527bda50c8297
https://pubmed.ncbi.nlm.nih.gov/16929934
https://pubmed.ncbi.nlm.nih.gov/16929934
Publikováno v:
American journal of physiology. Renal physiology. 290(5)
The epithelial Na+ channel (ENaC) is an end-effector of diverse cellular signaling cascades, including those with phosphatidylinositide second messengers. Recent evidence also suggests that in some instances, phospatidylinositides can directly intera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e20c949289af3a10e14565968c6b5720
https://pubmed.ncbi.nlm.nih.gov/16601296
https://pubmed.ncbi.nlm.nih.gov/16601296