Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Qiurong Chang"'
Autor:
Miao Li, Qiurong Chang, Ye Luo, Jiaping Pan, Ye Hu, Binya Liu, Mengmeng Ma, Qiaoling Wang, Yi Guo, Qian Wang
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
Background: Polycystic ovary syndrome (PCOS) is characterized by excess androgens, ovulatory dysfunction, and polycystic ovaries. The mechanisms underlying ovulatory and metabolic disorders in PCOS remain elusive, hampering therapeutic development. E
Externí odkaz:
https://doaj.org/article/b8d369ce4014497da1f3146906a34ba3
Autor:
Jianing Niu, Qiurong Chang, Junting Xu, Jinli Li, Wenqiang Liu, Zhiqin Chen, Xianting Jiao, Yi Guo, Xiaoming Teng
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
Embryo selection in in vitro fertilization–embryo transfer (IVF-ET) mostly relies on morphological assessment using a conventional microscope or the time-lapse monitoring system, which is not comprehensive. Inappropriate levels of reactive oxygen s
Externí odkaz:
https://doaj.org/article/12a0ebd5d2dd42eaa4151b7394952f6b
Autor:
Yi Guo, Jinli Li, Fengdan Hao, Yang Yang, Hao Yang, Qiurong Chang, Pengcheng Kong, Wenqiang Liu, Xianting Jiao, Xiaoming Teng
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2023)
BackgroundSemen quality is negatively correlated with male age and is mainly quantified by a routine semen analysis, which is descriptive and inconclusive. Sperm proteins or semen metabolites are used as the intermediate or end-products, reflecting c
Externí odkaz:
https://doaj.org/article/4af09496dadc4fa6be9382c0ecaa7139
Publikováno v:
Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics. 39(4)
To explore the genetic basis of a Chinese pedigree affected with Dyggve-Melchior-Clausen syndrome.Whole exome sequencing and Sanger sequencing were carried out to detect potential pathogenic variants associated with the syndrome. The function of cand
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bb65d1c22a8353b41308bc7e5f45f3e8
https://pubmed.ncbi.nlm.nih.gov/35446968
https://pubmed.ncbi.nlm.nih.gov/35446968
Autor:
Li Fu, Shangang Li, Huiyang Wang, Xuejin Chen, Jing Zhou, Qiurong Chang, Lili Liu, Yawei Gao, Ting Zhang, Liyun Yang, Yao Li
Publikováno v:
Theriogenology. 157:314-320
Successful fertilization by intracytoplasmic sperm injection (ICSI) is possible as long as the sperm genome is intact, even in the context of defective sperm or sustained adverse treatment. However, there are few reports on rescuing gene-modified mou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2df78521a83ceaf610018753edb4aff
https://doi.org/10.1016/j.theriogenology.2020.08.006
https://doi.org/10.1016/j.theriogenology.2020.08.006
Autor:
Lili Liu, Huiyang Wang, Fengying Xing, Jianchang Cao, Li Fu, Shangang Li, Qiurong Chang, Yao Li, Guofeng Yan, Zhengwen Ma, Xuejin Chen
Publikováno v:
Human Gene Therapy. 30:1079-1092
The application of CRISPR/Cas9 has opened a new era in gene therapy, making it possible to correct mutated genomes in vivo. Exon replacement can correct many mutations and has potential clinical va...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ce59ec4b4530b27bea7fe08a50fa05e5
https://doi.org/10.1089/hum.2019.037
https://doi.org/10.1089/hum.2019.037
Autor:
Xingxu Huang, Lili Liu, Jing Zhou, Qiurong Chang, Zhengwen Ma, Li Fu, Huiyang Wang, Fengying Xing, Shangang Li, Xuejin Chen, Zhenfu Fang, Yao Li, Wei-hua Jiang
Publikováno v:
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)
Scientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)
CRISPR/Cas9 has recently been developed as an efficient genome engineering tool. The rabbit is a suitable animal model for studies of metabolic diseases. In this study, we generated ATP7B site-directed point mutation rabbits to simulate a major mutat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1235a8badbbfb9b26d82cacb7d99be77
https://pubmed.ncbi.nlm.nih.gov/29358698
https://pubmed.ncbi.nlm.nih.gov/29358698