Zobrazeno 1 - 10
of 226
pro vyhledávání: '"Qiulian WU"'
Publikováno v:
Shipin gongye ke-ji, Vol 45, Iss 13, Pp 17-29 (2024)
Objective: The study was designed to test solvent extracts of Rubus suavissimus (RS) for compounds that regulate lipid metabolism and to measure their relative activity as quantitative markers of lipid metabolism-regulating activities based on the sp
Externí odkaz:
https://doaj.org/article/f881e9c96a6f4dd2b25086cdb57e1824
Autor:
Peng Lin, Wenyan Chen, Zhilin Long, Jichuan Yu, Jiayao Yang, Zhen Xia, Qiulian Wu, Xinyu Min, Jing Tang, Ya Cui, Fuyi Liu, Chun Wang, Jian Zheng, Wei Li, Jeremy N. Rich, Lei Li, Qi Xie
Publikováno v:
Cell Discovery, Vol 10, Iss 1, Pp 1-19 (2024)
Abstract Glioblastoma is one of the most lethal malignant cancers, displaying striking intratumor heterogeneity, with glioblastoma stem cells (GSCs) contributing to tumorigenesis and therapeutic resistance. Pharmacologic modulators of ubiquitin ligas
Externí odkaz:
https://doaj.org/article/7054dc9a7eae487eabc6c694ed88f91a
Autor:
Jinci Mai, Qiulian Wu, Huanhua Wu, Chunyuan Zeng, Yingxin Li, Jingjie Shang, Biao Wu, Qijun Cai, Junbi Du, Jian Gong
Publikováno v:
Lipids in Health and Disease, Vol 23, Iss 1, Pp 1-11 (2024)
Abstract Background Being overweight or obese has become a serious public health concern, and accurate assessment of body composition is particularly important. More precise indicators of body fat composition include visceral adipose tissue (VAT) mas
Externí odkaz:
https://doaj.org/article/db1688f901fe4749a9ab3307590018d5
Autor:
Lihui Liu, Ziyang Liu, Qinghua Liu, Wei Wu, Peng Lin, Xing Liu, Yuechuan Zhang, Dongpeng Wang, Briana C. Prager, Ryan C. Gimple, Jichuan Yu, Weixi Zhao, Qiulian Wu, Wei Zhang, Erzhong Wu, Xiaomin Chen, Jianjun Luo, Jeremy N. Rich, Qi Xie, Tao Jiang, Runsheng Chen
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract Glioblastoma (GBM) ranks among the most lethal of human cancers, containing glioma stem cells (GSCs) that display therapeutic resistance. Here, we report that the lncRNA INHEG is highly expressed in GSCs compared to differentiated glioma cel
Externí odkaz:
https://doaj.org/article/89d5aa57675b4f25a388ae2c629d485a
Transgelin Promotes Glioblastoma Stem Cell Hypoxic Responses and Maintenance Through p53 Acetylation
Autor:
Huan Li, Chao Song, Yang Zhang, Guohao Liu, Hailong Mi, Yachao Li, Zhiye Chen, Xiaoyu Ma, Po Zhang, Lidong Cheng, Peng Peng, Hongtao Zhu, Zirong Chen, Minhai Dong, Sui Chen, Hao Meng, QunGen Xiao, Honglian Li, Qiulian Wu, Baofeng Wang, Suojun Zhang, Kai Shu, Feng Wan, Dongsheng Guo, Wenchao Zhou, Lin Zhou, Feng Mao, Jeremy N. Rich, Xingjiang Yu
Publikováno v:
Advanced Science, Vol 11, Iss 7, Pp n/a-n/a (2024)
Abstract Glioblastoma (GBM) is a lethal cancer characterized by hypervascularity and necrosis associated with hypoxia. Here, it is found that hypoxia preferentially induces the actin‐binding protein, Transgelin (TAGLN), in GBM stem cells (GSCs). Me
Externí odkaz:
https://doaj.org/article/95216e81a5c74d7e8e6af9ccdf165215
Publikováno v:
Cancer Cell International, Vol 23, Iss 1, Pp 1-9 (2023)
Abstract Background Accumulating evidence demonstrated that nuclear factor erythroid 2-related factor 2 (NRF2) expression plays a crucial role in the proliferation, invasion and metastasis of hepatocellular carcinoma (HCC). However, research on the e
Externí odkaz:
https://doaj.org/article/be6f29d6a5d04089b4caa32ae44d49ee
Autor:
Ryan C. Gimple, Guoxin Zhang, Shuai Wang, Tengfei Huang, Jina Lee, Suchet Taori, Deguan Lv, Deobrat Dixit, Matthew E. Halbert, Andrew R. Morton, Reilly L. Kidwell, Zhen Dong, Briana C. Prager, Leo J.Y. Kim, Zhixin Qiu, Linjie Zhao, Qi Xie, Qiulian Wu, Sameer Agnihotri, Jeremy N. Rich
Publikováno v:
JCI Insight, Vol 8, Iss 6 (2023)
Glioblastoma is the most malignant primary brain tumor, the prognosis of which remains dismal even with aggressive surgical, medical, and radiation therapies. Glioblastoma stem cells (GSCs) promote therapeutic resistance and cellular heterogeneity du
Externí odkaz:
https://doaj.org/article/ec0fd42d418349639d81160bf89146e0
Autor:
Derrick Lee, Ryan C. Gimple, Xujia Wu, Briana C. Prager, Zhixin Qiu, Qiulian Wu, Vikas Daggubati, Aruljothi Mariappan, Jay Gopalakrishnan, Matthew R. Sarkisian, David R. Raleigh, Jeremy N. Rich
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 2 (2023)
Glioblastoma ranks among the most aggressive and lethal of all human cancers. Self-renewing, highly tumorigenic glioblastoma stem cells (GSCs) contribute to therapeutic resistance and maintain cellular heterogeneity. Here, we interrogated superenhanc
Externí odkaz:
https://doaj.org/article/9e622da572424f9dad2fb6932cf79adc
Autor:
Li Jiang, Yajing Hao, Changwei Shao, Qiulian Wu, Briana C. Prager, Ryan C. Gimple, Gabriele Sulli, Leo J.Y. Kim, Guoxin Zhang, Zhixin Qiu, Zhe Zhu, Xiang-Dong Fu, Jeremy N. Rich
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 6 (2022)
Glioblastoma (GBM) is the most common and lethal primary malignant brain tumor, containing GBM stem cells (GSCs) that contribute to therapeutic resistance and relapse. Exposing potential GSC vulnerabilities may provide therapeutic strategies against
Externí odkaz:
https://doaj.org/article/9e343997925d42dba86e8ff866779674
Dual Role of WISP1 in maintaining glioma stem cells and tumor-supportive macrophages in glioblastoma
Autor:
Weiwei Tao, Chengwei Chu, Wenchao Zhou, Zhi Huang, Kui Zhai, Xiaoguang Fang, Qian Huang, Aili Zhang, Xiuxing Wang, Xingjiang Yu, Haidong Huang, Qiulian Wu, Andrew E. Sloan, Jennifer S. Yu, Xiaoxia Li, George R. Stark, Jeremy N. Rich, Shideng Bao
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
The tumour microenvironment plays an important role in promoting glioblastoma. Here, the authors show that glioma stem cells secrete WISP1, which promotes both the survival of the stem cells and tumour-associated macrophages.
Externí odkaz:
https://doaj.org/article/80ed06b6daa44b72a61177b8c8e47066