Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Qiujun Qiu"'
Autor:
Qiujun Qiu, Sunhui Chen, Huining He, Jixiang Chen, Xinyi Ding, Dongdong Wang, Jiangang Yang, Pengcheng Guo, Yang Li, Jisu Kim, Jianyong Sheng, Chao Gao, Bo Yin, Shihao Zheng, Jianxin Wang
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 13, Iss 12, Pp 5091-5106 (2023)
Despite exciting achievements with some malignancies, immunotherapy for hypoimmunogenic cancers, especially glioblastoma (GBM), remains a formidable clinical challenge. Poor immunogenicity and deficient immune infiltrates are two major limitations to
Externí odkaz:
https://doaj.org/article/3527f99918d44dcbb638a2f5613534a2
Autor:
Jisu Kim, Ying Zhu, Sunhui Chen, Dongdong Wang, Shuya Zhang, Jiaxuan Xia, Shiyi Li, Qiujun QIU, Hyukjin Lee, Jianxin Wang
Publikováno v:
Journal of Nanobiotechnology, Vol 21, Iss 1, Pp 1-19 (2023)
Abstract Inhibition of tumor growth and normalization of immune responses in the tumor microenvironment (TME) are critical issues for improving cancer therapy. However, in the treatment of glioma, effective nanomedicine has limited access to the brai
Externí odkaz:
https://doaj.org/article/209b738d04624a42b433f3948191cff2
Autor:
Yang Li, Miaomiao Zhang, Shiyi Li, Longlong Zhang, Jisu Kim, Qiujun Qiu, Weigen Lu, Jianxin Wang
Publikováno v:
Asian Journal of Pharmaceutical Sciences, Vol 18, Iss 2, Pp 100783- (2023)
Cerebral ischemia-reperfusion injury (CI/RI) remains the main cause of disability and death in stroke patients due to lack of effective therapeutic strategies. One of the main issues related to CI/RI treatment is the presence of the blood-brain barri
Externí odkaz:
https://doaj.org/article/1e78d1420ce04c0fb2e36f548ff3acf9
Autor:
Chaoyang Lai, Cong Li, Mengyang Liu, Qiujun Qiu, Xiang Luo, Xinrong Liu, Ling Hu, Yihui Deng, Yanzhi Song
Publikováno v:
Asian Journal of Pharmaceutical Sciences, Vol 14, Iss 4, Pp 455-464 (2019)
Accelerated blood clearance (ABC) phenomenon is common in many PEGylated nanocarriers, whose mechanism has not been completely elucidated yet. In this study, the correlation between Kupffer cells (KCs) and ABC phenomenon has been studied by KCs-targe
Externí odkaz:
https://doaj.org/article/4ab3b855192140d19750ec167acfdee4
Autor:
Mei Lu, Qiujun Qiu, Xiang Luo, Xinrong Liu, Jing Sun, Cunyang Wang, Xiangyun Lin, Yihui Deng, Yanzhi Song
Publikováno v:
Asian Journal of Pharmaceutical Sciences, Vol 14, Iss 3, Pp 265-274 (2019)
Although active constituents extracted from plants show robust in vitro pharmacological effects, low in vivo absorption greatly limits the widespread application of these compounds. A strategy of using phyto-phospholipid complexes represents a promis
Externí odkaz:
https://doaj.org/article/d6b37ad6b2c140708b1fbce72b162682
Autor:
Xiang Luo, Ling Hu, Huangliang Zheng, Mingqi Liu, Xinrong Liu, Cong Li, Qiujun Qiu, Zitong Zhao, Xiaobo Cheng, Chaoyang Lai, Yuqing Su, Yihui Deng, Yanzhi Song
Publikováno v:
Drug Delivery, Vol 25, Iss 1, Pp 1200-1212 (2018)
Poly(sialic acid) (PSA) is a natural hydrophilic biodegradable and non-immunogenic biopolymer, receptors for its monomer are expressed on peripheral blood neutrophils (PBNs), which plays important roles in the progression and invasion of tumors. A po
Externí odkaz:
https://doaj.org/article/3fff596edbd044a2946dac9ea8aaa9b7
Publikováno v:
Journal of Controlled Release. 358:681-705
Autor:
Xinrong Liu, Xiaoxue Lai, Xiang Luo, Shuo Wang, Xinyang Yan, Yanzhi Song, Chuizhong Fan, Cong Li, Xin Gao, Qiujun Qiu, Yihui Deng
Publikováno v:
Journal of Controlled Release. 337:393-406
Immune checkpoint blockade (ICB) treatment is promising for the clinical therapy of numerous malignancies. However, most cancer patients rarely benefit from such single-agent immunotherapies because of the complexity of both the tumor and tumor micro
Autor:
Cong Li, Chuizhong Fan, Shuang Lu, Qiujun Qiu, Xin Gao, Xinyang Yan, Shuo Wang, Bing Zhao, Xinrong Liu, Yanzhi Song, Yihui Deng
Publikováno v:
Molecular pharmaceutics.
Immune checkpoint blockade (ICB) treatment for the clinical therapy of numerous malignancies has attracted widespread attention in recent years. Despite being a promising treatment option, developing complementary strategies to enhance the proportion
Autor:
Dejun She, Meihong Chai, Bo Yin, Jianxin Wang, Dongdong Wang, Huining He, Qiujun Qiu, Sunhui Chen, Dong Nyoung Heo
Publikováno v:
Frontiers of Chemical Science and Engineering. 16:536-545
Many scientific efforts have been made to penetrate the blood-brain barrier and target glioblastoma cells, but the outcomes have been limited. More attention should be given to local inhibition of recurrence after glioblastoma resection to meet real