Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Qiuhuan Yuan"'
Autor:
Han Liu, Bingchen Jiang, Rui Hua, Xuehao Liu, Bao Qiao, Xiangxin Zhang, Xilong Liu, Wenjun Wang, Qiuhuan Yuan, Bailu Wang, Shujian Wei, Yuguo Chen
Publikováno v:
Cardiovascular Diabetology, Vol 23, Iss 1, Pp 1-14 (2024)
Abstract Background Sodium-glucose cotransporter-2 inhibitors (SGLT2i) are now recommended for patients with heart failure, but the mechanisms that underlie the protective role of SGLT2i in cardiac remodeling remain unclear. Aldehyde dehydrogenase 2
Externí odkaz:
https://doaj.org/article/53dfa8dfb86c418596c46e2faf05375e
Publikováno v:
Cell Death and Disease, Vol 14, Iss 2, Pp 1-17 (2023)
Abstract The aberrant differentiation of valvular interstitial cells (VICs) to osteogenic lineages promotes calcified aortic valves disease (CAVD), partly activated by potentially destructive hemodynamic forces. These involve Rho A/ROCK1 signaling, a
Externí odkaz:
https://doaj.org/article/cf67ad299e794ad692696f7786d924c9
Autor:
Weikang Liu, Qiuhuan Yuan, Shengchuan Cao, Guoying Wang, Xiangguo Liu, Yanan Xia, Yuan Bian, Feng Xu, Yuguo Chen
Publikováno v:
Pharmacological Research, Vol 193, Iss , Pp 106815- (2023)
Cardiac fibrosis is a common pathophysiological remodeling process that occurs in a variety of cardiovascular diseases and greatly influences heart structure and function, progressively leading to the development of heart failure. However, to date, f
Externí odkaz:
https://doaj.org/article/3fece3a7f8f8476d893a612778a54873
Autor:
Ying Zhang, Ying Lv, Qingju Zhang, Xingfang Wang, Qi Han, Yan Liang, Simeng He, Qiuhuan Yuan, Jiaqi Zheng, Changchang Xu, Xiangxin Zhang, Zichen Wang, Huaxiang Yu, Li Xue, Jiali Wang, Feng Xu, Jiaojiao Pang, Yuguo Chen
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Cell survival or death is critical for cardiac function. Myocardial pyroptosis, as a newly recognized programmed cell death, remains poorly understood in sepsis. In this study, we evaluated the effect of aldehyde dehydrogenase (ALDH2) on myocardial p
Externí odkaz:
https://doaj.org/article/aad09b65ddc6412d84a533b63db914f3
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Pulmonary fibrosis is a progressive and intractable lung disease with fibrotic features that affects alveoli elasticity, which leading to higher rates of hospitalization and mortality worldwide. Pulmonary fibrosis is initiated by repetitive localized
Externí odkaz:
https://doaj.org/article/223faf746b224abdaa73977fb2ef94f2
Autor:
Shengchuan Cao, Qiuhuan Yuan, Qianqian Dong, Xilong Liu, Weikang Liu, Xiaoxuan Zhai, Chuanxin Zhang, Han Liu, Mengxiong Tang, Shujian Wei, Yuguo Chen
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Vascular smooth muscle cells (VSMCs) is a vital accelerator in the late phase of diabetic atherosclerosis, but the underlying mechanism remains unclear. The aim of our study was to investigate whether activin receptor-like kinase 7 (ALK7)-Smad2/3 pat
Externí odkaz:
https://doaj.org/article/e66d704f668a4b569d4205c73f59bafa
Autor:
Shukun Sun, Yu Han, Chuanxin Zhang, Han Liu, Bailu Wang, Shengchuan Cao, Qiuhuan Yuan, Shujian Wei, Yuguo Chen
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Background: Inflammatory disorder and acinar cell death contribute to the initiation and progression of severe acute pancreatitis (SAP). Adenosine kinase (ADK) has potential effects on both inflammation and cell death. However, the role of ADK in SAP
Externí odkaz:
https://doaj.org/article/25746a1331194f6191d6769c872e56bc
Autor:
Luyao Gao, Yuan Bian, Shengchuan Cao, Wentao Sang, Qun Zhang, Qiuhuan Yuan, Feng Xu, Yuguo Chen
Publikováno v:
Frontiers in Medicine, Vol 8 (2021)
Background: Patients with acute heart failure (AHF) who require continuous renal replacement therapy (CRRT) have a high risk of in-hospital mortality. It is clinically important to screen high-risk patients using a model or scoring system. This study
Externí odkaz:
https://doaj.org/article/a0cf0dad7b754d85967f2cb7cd9b5192
Autor:
Xiaoxuan Zhai, Wenjun Wang, Shukun Sun, Yu Han, Jiaxin Li, Shengchuan Cao, Ruochuan Li, Tonghui Xu, Qiuhuan Yuan, Jiali Wang, Shujian Wei, Yuguo Chen
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Background: Necroptosis is a vital regulator of myocardial ischemia/reperfusion (MI/R) injury. Meanwhile, 4-hydroxy-2-nonenal (4-HNE) is abundantly increased during MI/R injury. However, whether 4-HNE induces cardiomyocyte necroptosis during MI/R rem
Externí odkaz:
https://doaj.org/article/fbf6849bf0de4ef9b8b0e45afdb3a662
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Nitrosative stress, as an important oxygen metabolism disorder, has been shown to be closely associated with cardiovascular diseases, such as myocardial ischemia/reperfusion injury, aortic aneurysm, heart failure, hypertension, and atherosclerosis. N
Externí odkaz:
https://doaj.org/article/ae296f7ec27d49db8470fe010574ddc3