Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Qiufang Cheng"'
Autor:
Charles E Bane, Ivan Ivanov, Anton Matafonov, Kelli L Boyd, Qiufang Cheng, Edward R Sherwood, Erik I Tucker, Stephen T Smiley, Owen J T McCarty, Andras Gruber, David Gailani
Publikováno v:
PLoS ONE, Vol 11, Iss 4, p e0152968 (2016)
Sepsis, a systemic inflammatory response to infection, is often accompanied by abnormalities of blood coagulation. Prior work with a mouse model of sepsis induced by cecal ligation and puncture (CLP) suggested that the protease factor XIa contributed
Externí odkaz:
https://doaj.org/article/15e4234e34084d13b6001a61916bc58a
Autor:
Aleksandr Shamanaev, Maxim Litvak, Qiufang Cheng, Michal Ponczek, S. Kent Dickeson, Stephanie A. Smith, James H. Morrissey, David Gailani
Publikováno v:
Journal of Thrombosis and Haemostasis. 21:1567-1579
Autor:
Qiufang Cheng, Bassem M Mohammed, David Gailani, Anton Matafonov, Mao-fu Sun, Ingrid M. Verhamme, Kusumam Joseph, Allen P. Kaplan, Ivan B. Ivanov, S. Kent Dickeson
Publikováno v:
Blood. 135:558-567
Prekallikrein (PK) is the precursor of the trypsin-like plasma protease kallikrein (PKa), which cleaves kininogens to release bradykinin and converts the protease precursor factor XII (FXII) to the enzyme FXIIa. PK and FXII undergo reciprocal convers
Publikováno v:
Methods in Molecular Biology ISBN: 9781071613979
Methods in Molecular Biology
Methods Mol Biol
Methods in Molecular Biology
Methods Mol Biol
Evaluating prospective anticoagulants therapies in animal thrombosis and bleeding models are standard pre-clinical approaches. Mice are frequently used for initial evaluations because a variety of models have been developed in this well characterized
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbca4865d9d057b9a93e22cd1d0de345
https://doi.org/10.1007/978-1-0716-1398-6_59
https://doi.org/10.1007/978-1-0716-1398-6_59
Publikováno v:
Research and Practice in Thrombosis and Haemostasis. 6:e12841
Autor:
Bassem M. Mohammed, Dougald M. Monroe, Qiufang Cheng, Anton Matafonov, David Gailani, Joost C. M. Meijers
Publikováno v:
Journal of thrombosis and haemostasis, 16(10), 2044-2049. Wiley-Blackwell
Essentials Mice lacking factor IX (FIX) or factor XI (FXI) were tested in a saphenous vein bleeding model. FIX-deficient mice displayed a hemostatic defect and FXI-deficient mice were similar to wild type mice. Infusion of FXI or over-expression of F
Autor:
David Gailani, Shauna Mason, Daniel J. Sexton, Ivan B. Ivanov, Thomas Renné, Yasin Kokoye, Edward P. Feener, Anton Matafonov, Keith R. McCrae, Qiufang Cheng, S. Kent Dickeson
Publikováno v:
Thrombosis Research. 140:118-124
Studies with animal models implicate the plasma proteases factor XIIa (FXIIa) and α-kallikrein in arterial and venous thrombosis. As congenital deficiencies of factor XII (FXII) or prekallikrein (PK), the zymogens of FXIIa and α-kallikrein respecti
Autor:
S. Kent Dickeson, Andras Gruber, David Gailani, Ivan Ivanov, Mao Fu Sun, Anton Matafonov, Ingrid M. Verhamme, Suman Kundu, Bassem M. Mohammed, Keith R. McCrae, Qiufang Cheng
Publikováno v:
Blood. 133(10)
The plasma proteins factor XII (FXII) and prekallikrein (PK) undergo reciprocal activation to the proteases FXIIa and kallikrein by a process that is enhanced by surfaces (contact activation) and regulated by the serpin C1 inhibitor. Kallikrein cleav
Autor:
Qiufang Cheng, Jonas Emsley, Anton Matafonov, Ingrid M. Verhamme, Ivan Ivanov, Mao-fu Sun, S. Kent Dickeson, David Gailani
Publikováno v:
Blood. 129(11)
When blood is exposed to variety of artificial surfaces and biologic substances, the plasma proteins factor XII (FXII) and prekallikrein undergo reciprocal proteolytic conversion to the proteases αFXIIa and α-kallikrein by a process called contact