Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Qiudong Deng"'
Autor:
Meixiang Huang, Erica Modeste, Eric Dammer, Paola Merino, Georgia Taylor, Duc M. Duong, Qiudong Deng, Christopher J. Holler, Marla Gearing, Dennis Dickson, Nicholas T. Seyfried, Thomas Kukar
Publikováno v:
Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-25 (2020)
Abstract Heterozygous, loss-of-function mutations in the granulin gene (GRN) encoding progranulin (PGRN) are a common cause of frontotemporal dementia (FTD). Homozygous GRN mutations cause neuronal ceroid lipofuscinosis-11 (CLN11), a lysosome storage
Externí odkaz:
https://doaj.org/article/ddd6ed1211be478aa3e32f948993154b
Autor:
Michelle A. Johnson, Qiudong Deng, Georgia Taylor, Zachary T. McEachin, Anthony W.S. Chan, Jessica Root, Gary J. Bassell, Thomas Kukar
Publikováno v:
Neurobiology of Disease, Vol 146, Iss , Pp 105085- (2020)
Fused in sarcoma (FUS) is a RNA/DNA protein involved in multiple nuclear and cytoplasmic functions including transcription, splicing, mRNA trafficking, and stress granule formation. To accomplish these many functions, FUS must shuttle between cellula
Externí odkaz:
https://doaj.org/article/8d61940c44194c51b4c66fbe11eac637
Autor:
Srikant Rangaraju, Syed Ali Raza, Andrea Pennati, Qiudong Deng, Eric B. Dammer, Duc Duong, Michael W. Pennington, Malu G. Tansey, James J. Lah, Ranjita Betarbet, Nicholas T. Seyfried, Allan I. Levey
Publikováno v:
Journal of Neuroinflammation, Vol 14, Iss 1, Pp 1-20 (2017)
Abstract Background Kv1.3 potassium channels regulate microglial functions and are overexpressed in neuroinflammatory diseases. Kv1.3 blockade may selectively inhibit pro-inflammatory microglia in neurological diseases but the molecular and cellular
Externí odkaz:
https://doaj.org/article/d5f77f315f2a4869b27ffaa7ca022a2a
Autor:
Serena M. Dudek, Duc M. Duong, John R. Hepler, Nicholas T. Seyfried, Eric B. Dammer, Qiudong Deng, Kyle J. Gerber
Publikováno v:
J Proteome Res
The hippocampus is well established as an essential brain center for learning and memory. Within the hippocampus, recent studies show that area CA2 is important for social memory, and is an anomaly compared to its better understood neighboring region
Autor:
Meixiang Huang, Thomas Kukar, Paola Merino, Eric B. Dammer, Christopher J. Holler, Qiudong Deng, Nicholas T. Seyfried, Erica Modeste, Georgia L Taylor
Publikováno v:
Alzheimer's & Dementia. 16
Autor:
Qiudong Deng, Duc M. Duong, Thomas Kukar, Paola Merino, Georgia Taylor, Nicholas T. Seyfried, Christopher J. Holler, Dennis W. Dickson, Eric B. Dammer, Meixiang Huang, Erica Modeste, Marla Gearing
Publikováno v:
Acta Neuropathologica Communications
Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-25 (2020)
Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-25 (2020)
Heterozygous, loss-of-function mutations in the granulin gene (GRN) encoding progranulin (PGRN) are a common cause of frontotemporal dementia (FTD). Homozygous GRN mutations cause neuronal ceroid lipofuscinosis-11 (CLN11), a lysosome storage disease.
Autor:
Georgia Taylor, Jessica Root, Qiudong Deng, Michelle A. Johnson, Zachary T. McEachin, Thomas Kukar, Gary J. Bassell, Anthony W.S. Chan
Publikováno v:
Neurobiology of disease
Neurobiology of Disease, Vol 146, Iss, Pp 105085-(2020)
Neurobiology of Disease, Vol 146, Iss, Pp 105085-(2020)
Fused in sarcoma (FUS) is a RNA/DNA protein involved in multiple nuclear and cytoplasmic functions including transcription, splicing, mRNA trafficking, and stress granule formation. To accomplish these many functions, FUS must shuttle between cellula
Autor:
Meixiang Huang, Modeste, Erica, Dammer, Eric, Merino, Paola, Taylor, Georgia, Duong, Duc M., Qiudong Deng, Holler, Christopher J., Gearing, Marla, Dickson, Dennis, Seyfried, Nicholas T., Kukar, Thomas
Additional file 2. Table S2 summarizing the neuropathological, clinical diagnosis, age, sex, and other characterizes of human post-mortem samples used for immunostaining and ELISA.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17d1be88cb67ec63220d08bfb23cf2a2
Autor:
Meixiang Huang, Modeste, Erica, Dammer, Eric, Merino, Paola, Taylor, Georgia, Duong, Duc M., Qiudong Deng, Holler, Christopher J., Gearing, Marla, Dickson, Dennis, Seyfried, Nicholas T., Kukar, Thomas
Additional file 3. Compilation of multiple supplementary figures (S1–S7). Fig. S1 is a two-color heatmap showing the relationship between WGCNA modules and the bicor correlation of age. Fig. S2 contains multiple Box plots of WGCNA modules (M1, M2,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::369e63cd529bdd670d59f13d649186ca
Autor:
David S. Yu, Paul W. Doetsch, Ya Wang, Duc M. Duong, Qiudong Deng, Eric B. Dammer, Nicholas T. Seyfried, Erica Werner, Andrew Alter
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-10 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-10 (2019)
While evidence supporting the notion that exposures to heavy ion radiation increase the risk for cancer and other disease development is accumulating, the underlying biological mechanisms remain poorly understood. To identify novel phenotypes that pe