Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Qiuchen Chen"'
Autor:
Senxu Lu, Li Han, Xiaoyun Hu, Tong Sun, Dongping Xu, Yalun Li, Qiuchen Chen, Weifan Yao, Miao He, Zhenning Wang, Huizhe Wu, Minjie Wei
Publikováno v:
Journal of Hematology & Oncology, Vol 14, Iss 1, Pp 1-23 (2021)
Abstract Background Accumulating evidence shows that N6-methyladenine (m6A) modulators contribute to the etiology and progression of colorectal cancer (CRC). However, the exact mechanisms of m6A reader involved in glycolytic metabolism remain vague.
Externí odkaz:
https://doaj.org/article/4e1217b06a014e1caa21783e01cca7fd
Autor:
Huizhe Wu, Xiaoyun Hu, Yalun Li, Qiuchen Chen, Tong Sun, Yun Qiao, Wenyan Qin, Zhikun Wu, Boshi Fu, Haishan Zhao, Rui Zhang, Minjie Wei
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 21, Iss , Pp 764-779 (2020)
A growing number of studies have focused on the involvement of non-coding RNAs (ncRNAs) in the internal ribosome entry site (IRES)-mediated translation in tumorigenesis; however, the underlying mechanisms in colorectal cancer (CRC) remain elusive. In
Externí odkaz:
https://doaj.org/article/24ea662b880c4a82956f730b0fff077c
Autor:
Huizhe Wu, Wenyan Qin, Senxu Lu, Xiufang Wang, Jing Zhang, Tong Sun, Xiaoyun Hu, Yalun Li, Qiuchen Chen, Yuanhe Wang, Haishan Zhao, Haiyan Piao, Rui Zhang, Minjie Wei
Publikováno v:
Molecular Cancer, Vol 19, Iss 1, Pp 1-22 (2020)
Abstract Background Increasing evidence supports the role of small nucleolar RNAs (snoRNAs) and long non-coding RNAs (lncRNAs) as master gene regulators at the epigenetic modification level. However, the underlying mechanism of these functional ncRNA
Externí odkaz:
https://doaj.org/article/3a728503522f44468fe2331f31879816
Autor:
Xiaoyun Hu, Qiuchen Chen, Hao Guo, Kuo Li, Boshi Fu, Yu Chen, Haishan Zhao, Minjie Wei, Yalun Li, Huizhe Wu
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
A major complication of colorectal cancer (CRC), one of the most common and fatal types of cancers, is secondary liver metastasis. For patients with this fate, there are very few biomarkers available in clinical application, and the disease remains i
Externí odkaz:
https://doaj.org/article/8570669f0cc44c61bfa008998b467b02
Autor:
Wenyan Qin, Xiaodong Wang, Yilin Wang, Yalun Li, Qiuchen Chen, Xiaoyun Hu, Zhikun Wu, Pengfei Zhao, Shanqiong Li, Haishan Zhao, Weifan Yao, Jian Ding, Minjie Wei, Huizhe Wu
Publikováno v:
Cancer Cell International, Vol 19, Iss 1, Pp 1-12 (2019)
Abstract Background The long non-coding RNA H19 plays critical roles in cancer occurrence, development, and progression. The present study is for the first time to evaluate the association of genetic variations in the H19 promoter region with advance
Externí odkaz:
https://doaj.org/article/998d39b2cd1b44f29e242db44954d51c
Autor:
Minjie Wei, Huizhe Wu, Olufunmilayo I. Olapade, Jianjun Chen, Yong Liu, Feng Jin, Weifan Yao, Haishan Zhao, Jing Zhang, Binbin Wei, Yilin Wang, Miao He, Shu Guan, Xiaoyun Hu, Xiaolan Deng, Qiuchen Chen
ZEB1 (a positive enhancer) and KLF5 (a negative silencer) affect transcription factors and play inherently conserved roles in tumorigenesis and multidrug resistance. In humans, the rs2295080T-allele at the mTOR promoter locus has been associated with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bb1ea67fc74ec08b0ee4eb4dacc973c5
https://doi.org/10.1158/1541-7786.c.6540393.v1
https://doi.org/10.1158/1541-7786.c.6540393.v1
Autor:
Minjie Wei, Huizhe Wu, Olufunmilayo I. Olapade, Jianjun Chen, Yong Liu, Feng Jin, Weifan Yao, Haishan Zhao, Jing Zhang, Binbin Wei, Yilin Wang, Miao He, Shu Guan, Xiaoyun Hu, Xiaolan Deng, Qiuchen Chen
Table S1. Frequencies of mTOR promoter polymorphisms in patients with breast cancer and healthy controls Table S2. Frequency distribution of mTOR haplotypes and their associations with the risk of developing breast cancer Table S3. Association of mTO
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09310fae570651dd20f0144c67818bfd
https://doi.org/10.1158/1541-7786.22512960.v1
https://doi.org/10.1158/1541-7786.22512960.v1
Autor:
Senxu Lu, Mingyan Liu, Wenyan Qin, Tong Sun, Weifan Yao, Qiuchen Chen, Huizhe Wu, Minjie Wei, Dongping Xu, Yalun Li, Yuanhe Wang, Zhikun Wu, Yutong Wu, Xiufang Wang, Xiaoyun Hu
Publikováno v:
Aging (Albany NY)
Increasing evidence supports long non-coding RNA-ZFAS1 as master protein regulators involved in a variety of human cancers. However, the molecular mechanism is not fully understood in colorectal cancer (CRC) and remains to be elucidated. Here, we unc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58807d2504fcd764d1dde8c4b3672b1e
https://doi.org/10.18632/aging.103875
https://doi.org/10.18632/aging.103875
Autor:
Zhikun Wu, Rui Zhang, Tong Sun, Xiaoyun Hu, Haishan Zhao, Qiuchen Chen, Minjie Wei, Huizhe Wu, Wenyan Qin, Boshi Fu, Yun Qiao, Yalun Li
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 21, Iss, Pp 764-779 (2020)
Molecular Therapy. Nucleic Acids
Molecular Therapy. Nucleic Acids
A growing number of studies have focused on the involvement of non-coding RNAs (ncRNAs) in the internal ribosome entry site (IRES)-mediated translation in tumorigenesis; however, the underlying mechanisms in colorectal cancer (CRC) remain elusive. In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c36cd988a238bef111503051669092a6
http://www.sciencedirect.com/science/article/pii/S2162253120301980
http://www.sciencedirect.com/science/article/pii/S2162253120301980
Autor:
Qiuchen Chen, Hao Guo, Tong Sun, Senxu Lu, Xiufang Wang, Dongping Xu, Yilin Wang, Xiaoyun Hu, Boshi Fu, Wenyan Qin, Huizhe Wu, Weifan Yao, Xiangyu Ding, Zhikun Wu, Yalun Li, Yuanhe Wang, Yutong Wu, Minjie Wei
Publikováno v:
Oncogene. 39:5358-5372
Increasing evidence supports that long noncoding RNAs (lncRNAs) act as master regulators involved in tumorigenesis and development at the N6-methyladenine (m6A) epigenetic modification level. However, the underlying regulatory mechanism in breast can
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::792f4dacfef621f6a1b1603e55f7ddc6
https://doi.org/10.1038/s41388-020-1338-9
https://doi.org/10.1038/s41388-020-1338-9