Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Qiucen Zhang"'
Autor:
Thuy T. M. Ngo, Jejoong Yoo, Qing Dai, Qiucen Zhang, Chuan He, Aleksei Aksimentiev, Taekjip Ha
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-9 (2016)
Cytosine modifications are important epigenetic markers yet their physical influence on DNA is not well understood. Here, Ngo et al. show that different alterations affect DNA flexibility, suggesting a mechanism where modifications change accessibili
Externí odkaz:
https://doaj.org/article/0efdd629e1b94ac2be9c3b50a9bcee44
Publikováno v:
New Journal of Physics, Vol 16, Iss 4, p 045005 (2014)
One of the physiological responses of bacteria to external stress is to assemble into a biofilm. The formation of a biofilm greatly increases a bacterial population's resistance to a hostile environment by shielding cells, for example, from antibioti
Externí odkaz:
https://doaj.org/article/6bf8976565ee4660a43f9344bbfcbb07
Autor:
Jingyi Fei, Taekjip Ha, Divya Balasubramanian, Ido Golding, Carin K. Vanderpool, Digvijay Singh, Qiucen Zhang, Seongjin Park
Publikováno v:
Science. 347:1371-1374
RNA kinetics may define regulatory hierarchy The double-helical structure of DNA suggests immediately how nucleic acid polymers can recognize and bind to homologous sequences. Target recognition by RNA is vital in many biological processes. Fei et al
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b837699bf0eb4c8a75a7c6ea60a80cbe
https://doi.org/10.1126/science.1258849
https://doi.org/10.1126/science.1258849
Publikováno v:
Cell. 160:1135-1144
SummaryDynamics of the nucleosome and exposure of nucleosomal DNA play key roles in many nuclear processes, but local dynamics of the nucleosome and its modulation by DNA sequence are poorly understood. Using single-molecule assays, we observed that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02e0309d30bc439af0e0aa4678a344a2
https://doi.org/10.1016/j.cell.2015.02.001
https://doi.org/10.1016/j.cell.2015.02.001
Publikováno v:
Advanced Drug Delivery Reviews. :217-224
Drug development faces its nemesis in the form of drug resistance. The rate of bacterial resistance to antibiotics, or tumor resistance to chemotherapy decisively depends on the surrounding heterogeneous tissue. However, in vitro drug testing is almo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b25371a8abd0de9980ae7aac5904693b
https://doi.org/10.1016/j.addr.2014.02.005
https://doi.org/10.1016/j.addr.2014.02.005
Autor:
Qiucen Zhang1, Lambert, Guillaume1, Liao, David2, Hyunsung Kim3, Robin, Kristelle4, Chih-kuan Tung5, Pourmand, Nader3, Austin, Robert H.1,4 austin@princeton.edu
Publikováno v:
Science. 9/23/2011, Vol. 333 Issue 6050, p1764-1767. 4p.
Autor:
Jejoong Yoo, Chuan He, Taekjip Ha, Qiucen Zhang, Qing Dai, Thuy T.M. Ngo, Aleksei Aksimentiev
Publikováno v:
Nature Communications
Nature Communications, Vol 7, Iss 1, Pp 1-9 (2016)
Nature Communications, Vol 7, Iss 1, Pp 1-9 (2016)
Cytosine can undergo modifications, forming 5-methylcytosine (5-mC) and its oxidized products 5-hydroxymethylcytosine (5-hmC), 5-formylcytosine (5-fC) and 5-carboxylcytosine (5-caC). Despite their importance as epigenetic markers and as central playe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4b0220190a89b591029e0b9253ada11
http://europepmc.org/articles/PMC4770088
http://europepmc.org/articles/PMC4770088
Autor:
Qiucen Zhang, Robert H. Austin
Publikováno v:
BioNanoScience. 2:277-286
Stem cell research can significantly benefit from recent advances of microfluidics technology. In a rationally designed microfluidics device, analyses of stem cells can be done in a much deeper and wider way than in a conventional tissue culture dish
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a112351ffda8c3b5bfab47456c13b61c
https://doi.org/10.1007/s12668-012-0051-8
https://doi.org/10.1007/s12668-012-0051-8
Autor:
Qiucen Zhang, Robert H. Austin
Publikováno v:
Annual Review of Condensed Matter Physics. 3:363-382
It is a common mistake to view cancer as a single disease with a single possible cure which we have just not found yet. In reality cancer takes on many forms that share a common symptom: uncontrolled cell growth and successful invasion of cancer colo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7c16f604e0b0d96ec349f04ddfb1f7cf
https://doi.org/10.1146/annurev-conmatphys-020911-125109
https://doi.org/10.1146/annurev-conmatphys-020911-125109
Autor:
Nader Pourmand, Kristelle I L Bougot robin, Chih-kuan Tung, Qiucen Zhang, Robert H. Austin, Guillaume Lambert, David Liao, Hyunsung John Kim
Publikováno v:
Science. 333:1764-1767
The emergence of bacterial antibiotic resistance is a growing problem, yet the variables that influence the rate of emergence of resistance are not well understood. In a microfluidic device designed to mimic naturally occurring bacterial niches, resi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b0319ba4c2569288ba4423f2551a5596
https://doi.org/10.1126/science.1208747
https://doi.org/10.1126/science.1208747