Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Qiu‐Zhi Zhou"'
Autor:
Hui-Yang Lei, Gui-Lin Pi, Ting He, Rui Xiong, Jing-Ru Lv, Jia-Le Liu, Dong-Qin Wu, Meng-Zhu Li, Kun Shi, Shi-Hong Li, Na-Na Yu, Yang Gao, Hui-Ling Yu, Lin-Yu Wei, Xin Wang, Qiu-Zhi Zhou, Pei-Lin Zou, Jia-Yang Zhou, Ying-Zhou Liu, Nai-Ting Shen, Jie Yang, Dan Ke, Qun Wang, Gong-Ping Liu, Xi-Fei Yang, Jian-Zhi Wang, Ying Yang
Publikováno v:
Military Medical Research, Vol 11, Iss 1, Pp 1-24 (2024)
Abstract Background Episodic memory loss is a prominent clinical manifestation of Alzheimer’s disease (AD), which is closely related to tau pathology and hippocampal impairment. Due to the heterogeneity of brain neurons, the specific roles of diffe
Externí odkaz:
https://doaj.org/article/df673dbc95c04f9d9dc2c62b7ff993ba
Autor:
Meng-Zhu Li, En-Jie Liu, Qiu-Zhi Zhou, Shi-Hong Li, Shi-Jie Liu, Hai-Tao Yu, Qi-Hang Pan, Fei Sun, Ting He, Wei-Jin Wang, Dan Ke, Yu-Qi Feng, Jun Li, Jian-Zhi Wang
Publikováno v:
Military Medical Research, Vol 9, Iss 1, Pp 1-16 (2022)
Abstract Background Autophagy dysfunction plays a crucial role in tau accumulation and neurodegeneration in Alzheimer’s disease (AD). This study aimed to investigate whether and how the accumulating tau may in turn affect autophagy. Methods The pri
Externí odkaz:
https://doaj.org/article/c3d580c51c4a4c6a9ce76531a6abec8a
Autor:
Jia‐Zhao Xie, Yao Zhang, Shi‐Hong Li, Hui Wei, Hui‐Ling Yu, Qiu‐Zhi Zhou, Lin‐Yu Wei, Dan Ke, Qun Wang, Ying Yang, Jian‐Zhi Wang
Publikováno v:
Clinical and Translational Medicine, Vol 12, Iss 8, Pp n/a-n/a (2022)
Abstract Background Human Tau (hTau) accumulation and synapse loss are two pathological hallmarks of tauopathies. However, whether and how hTau exerts toxic effects on synapses remain elusive. Methods Mutated hTau (P301S) was overexpressed in the N2a
Externí odkaz:
https://doaj.org/article/637026b5410d440c99515a2c36a9eb46
Autor:
Zhi-Peng Xu, Su-Lian Yang, Shi Zhao, Cheng-Hong Zheng, Hong-Hua Li, Yao Zhang, Rong-Xi Huang, Meng-Zhu Li, Yuan Gao, Shu-Juan Zhang, Pei-Yan Zhan, Li-Fang Zhang, Lin Deng, Sheng Wei, Yan-Chao Liu, Jing-Wang Ye, Hu-Jun Ren, Na Li, Cai-Xia Kong, Xin Wang, Lin Fang, Qiu-Zhi Zhou, Hong-Wei Jiang, Jing-Rong Li, Qun Wang, Dan Ke, Gong-Ping Liu, Jian-Zhi Wang
Publikováno v:
EBioMedicine, Vol 5, Iss C, Pp 105-113 (2016)
Background: Both type 2 diabetes mellitus (T2DM) and Alzheimer's disease (AD) are common age-associated disorders and T2DM patients show an increased risk to suffer from AD, however, there is currently no marker to identify who in T2DM populations wi
Externí odkaz:
https://doaj.org/article/07cfe083271e425fa8949f178032c651
Autor:
Meng-Zhu Li, En-Jie Liu, Qiu-Zhi Zhou, Shi-Hong Li, Shi-Jie Liu, Hai-Tao Yu, Qi-Hang Pan, Fei Sun, Ting He, Wei-Jin Wang, Dan Ke, Yu-Qi Feng, Jun Li, Jian-Zhi Wang
Publikováno v:
Military Medical Research. 9(1)
Background Autophagy dysfunction plays a crucial role in tau accumulation and neurodegeneration in Alzheimer’s disease (AD). This study aimed to investigate whether and how the accumulating tau may in turn affect autophagy. Methods The primary hipp