Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Qishi Fan"'
Autor:
Xuqian Fang, Xiangfan Liu, Ling Yao, Changqiang Chen, Jiafei Lin, Peihua Ni, Xinmin Zheng, Qishi Fan
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e107134 (2014)
Mounting evidence suggests that the FAK N-terminal (FERM) domain controls FAK phosphorylation and function; however, little is known regarding the role of the C terminal (FAT) domain in FAK regulation. We identified a patient-derived FAK mutant, in w
Externí odkaz:
https://doaj.org/article/16b0a605bc39473faf1f4320239441ae
Autor:
Peihua Ni, Hong Xu, Changqiang Chen, Jiayi Wang, Xiangfan Liu, Yiqun Hu, Qishi Fan, Zhaoyuan Hou, Yang Lu
Publikováno v:
PLoS ONE, Vol 8, Iss 6 (2013)
Externí odkaz:
https://doaj.org/article/fb019fa317194f75a82d8d48b24a6918
Autor:
Peihua Ni, Hong Xu, Changqiang Chen, Jiayi Wang, Xiangfan Liu, Yiqun Hu, Qishi Fan, Zhaoyuan Hou, Yang Lu
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e50502 (2012)
DRAM is a lysosomal membrane protein and is critical for p53-mediated autophagy and apoptosis. DRAM has a potential tumor-suppressive function and is downregulated in many human cancers. However, the regulation of DRAM expression is poorly described
Externí odkaz:
https://doaj.org/article/a81ebceac22541cda3438737ca0c8773
Autor:
Jingru Wang, Qishi Fan
Publikováno v:
Journal of Physics: Conference Series. 1802:032036
Machine learning is known as the most popular methodology to do prediction on large data set while NBA’s data sets consists of plentiful statistics. Since predictions of various events are important, our research would investigate whether machine l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::16d3192886698f497f2d55b32a61b916
https://doi.org/10.1088/1742-6596/1802/3/032036
https://doi.org/10.1088/1742-6596/1802/3/032036
Autor:
Xiangfan Liu, Changqiang Chen, Zhidong Gu, Ling Yao, Qishi Fan, Peihua Ni, Xin-Min Zheng, Xu-Qian Fang
Publikováno v:
Biochemical and Biophysical Research Communications. 443:363-369
Focal adhesion kinase (FAK) regulates cell adhesion, migration, proliferation, and survival. We identified a novel splicing mutant, FAK-Del33 (exon 33 deletion, KF437463), in both breast and thyroid cancers through colony sequencing. Considering the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eefa6963d5ea766e7072d2a8e9fe24c1
https://doi.org/10.1016/j.bbrc.2013.11.134
https://doi.org/10.1016/j.bbrc.2013.11.134
Autor:
Junhao Mao, Yingying Wei, Hongkai Ji, Joo-Seop Park, Mihir Rajurkar, Jennifer L. Cotton, Qishi Fan, Brian C. Lewis, Jiayi Wang
Publikováno v:
Molecular Cell. 51:211-225
Dysregulation of Wnt signaling is closely associated with human liver tumorigenesis. However, liver cancer-specific Wnt transcriptional programs and downstream effectors remain poorly understood. Here, we identify tribbles homolog 2 (TRIB2) as a dire
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8da0448bc4dfedcfab012e7317fb1ee
https://doi.org/10.1016/j.molcel.2013.05.013
https://doi.org/10.1016/j.molcel.2013.05.013
Publikováno v:
International Journal of Oncology
PTPRA is reported to be involved in cancer development and progression through activating the Src family kinase (SFK) signaling pathways, however, the roles of PTPRA in the squamous cell lung cancer (SCC) development are unclear. The purpose of this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a65a78b5212509383c8307da91cd53b
https://pubmed.ncbi.nlm.nih.gov/28656243
https://pubmed.ncbi.nlm.nih.gov/28656243
Autor:
Zhidong Gu, Qishi Fan, Junjie Xie, Zhecheng Zhu, Bing Chen, Baiyong Shen, Xiaxing Deng, Hao Chen, Chenghong Peng, Yan-Yan Song, Weixia Zhang
Publikováno v:
European Journal of Pharmaceutical Sciences. 47:636-641
Mycophenolate Mofetil (MMF) is widely used in preventing acute rejection in liver transplantation. Only free MPA (fMPA) can exert the pharmacological effect. In this study, we aimed to develop the new model which could be best fit to predict the fMPA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a92548ab02d0ce0a9b16698544d1c5d
https://doi.org/10.1016/j.ejps.2012.08.001
https://doi.org/10.1016/j.ejps.2012.08.001
Publikováno v:
Molecular and Cellular Biochemistry. 359:17-23
TIGAR expression resulted in down-regulation of glycolysis, reduction of intracellular levels of reactive oxygen species, and protection from apoptosis. Despite biological importance, its promoter has not yet been characterized. In this study, we cha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee382fdb2cda4d9e4d9f873d2abdc613
https://doi.org/10.1007/s11010-011-0993-0
https://doi.org/10.1007/s11010-011-0993-0
Autor:
Xiangfan Liu, Changqiang Chen, Yongxia Qiao, Zhidong Gu, Ning Chen, Jiafei Lin, Jiayi Wang, Qishi Fan, Peihua Ni
Publikováno v:
Nucleic Acids Research
CD166/ALCAM plays an important role in tumor aggression and progression as well as protecting cancer cells against apoptosis and autophagy. However, the mechanism by which pro-cell death signals control CD166 expression remains unclear. Here we show
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c0fd19a8ab15a3461179ccdbe9a49ab
https://doi.org/10.1093/nar/gkr302
https://doi.org/10.1093/nar/gkr302