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pro vyhledávání: '"Qirat F, Ashraf"'
Autor:
Péter Ábrányi-Balogh, Dávid Bajusz, Zoltán Orgován, Aaron B. Keeley, László Petri, Nikolett Péczka, Tibor Viktor Szalai, Gyula Pálfy, Márton Gadanecz, Emma K. Grant, Tímea Imre, Tamás Takács, Ivan Ranđelović, Marcell Baranyi, András Marton, Gitta Schlosser, Qirat F. Ashraf, Elvin D. de Araujo, Tamás Karancsi, László Buday, József Tóvári, András Perczel, Jacob T. Bush, György M. Keserű
Publikováno v:
Communications Chemistry, Vol 7, Iss 1, Pp 1-13 (2024)
Abstract Fragment screening is a popular strategy of generating viable chemical starting points especially for challenging targets. Although fragments provide a better coverage of chemical space and they have typically higher chance of binding, their
Externí odkaz:
https://doaj.org/article/0a79f05dcd144d4ba343eaa1f806db99
Autor:
Qirat F. Ashraf, Erica J. Quilates, Olasunkanmi O. Olaoye, Elvin D. de Araujo, Patrick T. Gunning
Publikováno v:
Methods in Molecular Biology ISBN: 9781071627877
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c5eec15bdbd18641dc0e0706d677d2e4
https://doi.org/10.1007/978-1-0716-2788-4_31
https://doi.org/10.1007/978-1-0716-2788-4_31
Autor:
Qirat F, Ashraf, Erica J, Quilates, Olasunkanmi O, Olaoye, Elvin D, de Araujo, Patrick T, Gunning
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2589
Histone deacetylase 6 (HDAC6) is an emerging clinical target for the treatment of several hematological cancers and central nervous system disorders. HDAC6 catalyzes the deacetylation of lysine residues on substrates such as tubulin, with profound im